Bedaquiline, an FDA-approved drug, inhibits mitochondrial ATP production and metastasis in vivo, by targeting the gamma subunit (ATP5F1C) of the ATP synthase
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Bedaquiline, an FDA-approved drug, inhibits mitochondrial ATP production and metastasis in vivo, by targeting the gamma subunit (ATP5F1C) of the ATP synthase
Authors
Keywords
-
Journal
CELL DEATH AND DIFFERENTIATION
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-05-13
DOI
10.1038/s41418-021-00788-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- First-in-class candidate therapeutics that target mitochondria and effectively prevent cancer cell metastasis: mitoriboscins and TPP compounds
- (2020) Béla Ózsvári et al. Aging-US
- Deferiprone (DFP) Targets Cancer Stem Cell (CSC) Propagation by Inhibiting Mitochondrial Metabolism and Inducing ROS Production
- (2020) Marco Fiorillo et al. Cells
- A Myristoyl Amide Derivative of Doxycycline Potently Targets Cancer Stem Cells (CSCs) and Prevents Spontaneous Metastasis, Without Retaining Antibiotic Activity
- (2020) Béla Ózsvári et al. Frontiers in Oncology
- Bedaquiline inhibits the yeast and human mitochondrial ATP synthases
- (2020) Min Luo et al. Communications Biology
- “Energetic” Cancer Stem Cells (e-CSCs): A New Hyper-Metabolic and Proliferative Tumor Cell Phenotype, Driven by Mitochondrial Energy
- (2019) Marco Fiorillo et al. Frontiers in Oncology
- Cancer stem cells (CSCs): metabolic strategies for their identification and eradication
- (2018) Ernestina M. De Francesco et al. BIOCHEMICAL JOURNAL
- Bergamot natural products eradicate cancer stem cells (CSCs) by targeting mevalonate, Rho-GDI-signalling and mitochondrial metabolism
- (2018) Marco Fiorillo et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- A mitochondrial based oncology platform for targeting cancer stem cells (CSCs): MITO-ONC-RX
- (2018) Federica Sotgia et al. CELL CYCLE
- Oxidative phosphorylation: regulation and role in cellular and tissue metabolism
- (2017) David F. Wilson JOURNAL OF PHYSIOLOGY-LONDON
- Erratum: Cancer metabolism: a therapeutic perspective
- (2017) Ubaldo E. Martinez-Outschoorn et al. Nature Reviews Clinical Oncology
- Exercise Metabolism: Fuels for the Fire
- (2017) Mark Hargreaves et al. Cold Spring Harbor Perspectives in Medicine
- Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)
- (2016) Marco Fiorillo et al. Aging-US
- A Multisite-Binding Switchable Fluorescent Probe for Monitoring Mitochondrial ATP Level Fluctuation in Live Cells
- (2015) Lu Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Torque Transmission Mechanism via DELSEED Loop of F1-ATPase
- (2015) Rikiya Watanabe et al. BIOPHYSICAL JOURNAL
- Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease
- (2015) Rebecca Lamb et al. Oncotarget
- High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant
- (2015) Gillian Farnie et al. Oncotarget
- Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition
- (2015) Rebecca Lamb et al. Oncotarget
- Torque Generation Mechanism of F1-ATPase upon NTP Binding
- (2014) Hidenobu C. Arai et al. BIOPHYSICAL JOURNAL
- ATP synthesis and storage
- (2012) Massimo Bonora et al. Purinergic Signalling
- Paul D. Boyer—Nobel Prize for Work on ATP Synthase
- (2011) Marc A. Shampo et al. MAYO CLINIC PROCEEDINGS
- Oxidative phosphorylation is impaired by prolonged hypoxia in breast and possibly in cervix carcinoma
- (2010) Sara Rodríguez-Enríquez et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
- (2009) Balazs Györffy et al. BREAST CANCER RESEARCH AND TREATMENT
- The Double Life of ATP
- (2009) Baljit S. Khakh et al. SCIENTIFIC AMERICAN
- Karl Lohmann and the Discovery of ATP
- (2008) Peter Langen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More