PP2Acα promotes macrophage accumulation and activation to exacerbate tubular cell death and kidney fibrosis through activating Rap1 and TNFα production

Loss of myeloid-specific protein phosphatase 2A enhances lung injury and fibrosis and results in IL-10 dependent sensitization of epithelial cell apoptosis

(2019) Lei Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis

(2019) Yi Wen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis

(2017) Jiafa Ren et al.   JOURNAL OF PATHOLOGY

Wnt/ β -Catenin–Promoted Macrophage Alternative Activation Contributes to Kidney Fibrosis

(2017) Ye Feng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI

(2016) J. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis

(2016) Yinhua Ni et al.   Nutrients

Tumor Necrosis Factor-α Produced in the Kidney Contributes to Angiotensin II–dependent Hypertension

(2014) Jiandong Zhang et al.   HYPERTENSION

IL-4 and IL-13 inhibit IL-1β and TNF-α induced kinin B1and B2receptors through a STAT6-dependent mechanism

(2013) PPC Souza et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protein Kinase A-dependent Phosphorylation of Rap1 Regulates Its Membrane Localization and Cell Migration

(2013) Maho Takahashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic kidney disease: global dimension and perspectives

(2013) Vivekanand Jha et al.   LANCET

Molecular Mechanisms Underlying Cardiac Protein Phosphatase 2A Regulation in Heart

(2012) Sean T. DeGrande et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Protein Phosphatase 2A Catalytic Subunit α (PP2Acα) Maintains Survival of Committed Erythroid Cells in Fetal Liver Erythropoiesis through the STAT5 Pathway

(2011) Weiqian Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis

(2011) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

c-fms blockade reverses glomerular macrophage infiltration and halts development of crescentic anti-GBM glomerulonephritis in the rat

(2011) Yingjie Han et al.   LABORATORY INVESTIGATION

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

Macrophages and Immunologic Inflammation of the Kidney

(2010) Jeremy S. Duffield   SEMINARS IN NEPHROLOGY

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Bone Marrow Ly6Chigh Monocytes Are Selectively Recruited to Injured Kidney and Differentiate into Functionally Distinct Populations

(2009) S. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat

(2009) Frank Y Ma et al.   LABORATORY INVESTIGATION

Macrophage diversity in renal injury and repair

(2008) Sharon D. Ricardo et al.   JOURNAL OF CLINICAL INVESTIGATION