The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation

Neutrophils as emerging therapeutic targets

(2020) Tamás Németh et al.   NATURE REVIEWS DRUG DISCOVERY

Tensile force transmitted through LFA‐1 bonds mechanoregulate neutrophil inflammatory response

(2020) Vasilios A. Morikis et al.   JOURNAL OF LEUKOCYTE BIOLOGY

ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense

(2020) Derayvia Grimes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extratubular Polymerized Uromodulin Induces Leukocyte Recruitment and Inflammation In Vivo

(2020) Roland Immler et al.   Frontiers in Immunology

Ion Channel Conformations Regulate Integrin-Dependent Signaling

(2019) Andrea Becchetti et al.   TRENDS IN CELL BIOLOGY

CRAC channel regulation of innate immune cells in health and disease

(2019) Regina A. Clemens et al.   CELL CALCIUM

Fighting rheumatoid arthritis: Kv1.3 as a therapeutic target

(2019) Antonio Serrano-Albarrás et al.   BIOCHEMICAL PHARMACOLOGY

Src family kinase-mediated vesicle trafficking is critical for neutrophil basement membrane penetration

(2019) Ina Rohwedder et al.   HAEMATOLOGICA

The secret life of ion channels: Kv1.3 potassium channels and proliferation

(2018) M. Teresa Pérez-García et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Calcium signalling and related ion channels in neutrophil recruitment and function

(2018) Roland Immler et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Kv1.3 activity perturbs the homeostatic properties of astrocytes in glioma

(2018) Alfonso Grimaldi et al.   Scientific Reports

Neutrophil Mechanosignaling Promotes Integrin Engagement With Endothelial Cells and Motility Within Inflamed Vessels

(2018) Vasilios A. Morikis et al.   Frontiers in Immunology

Kv1.3 potassium channel mediates macrophage migration in atherosclerosis by regulating ERK activity

(2016) Xiao-Hong Kan et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane

(2016) Angela R.M. Kurz et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophils in animal models of autoimmune disease

(2016) Tamás Németh et al.   SEMINARS IN IMMUNOLOGY

Human neutrophils in auto-immunity

(2016) Nathalie Thieblemont et al.   SEMINARS IN IMMUNOLOGY

PreImplantation factor prevents atherosclerosis via its immunomodulatory effects without affecting serum lipids

(2016) Y. C. Chen et al.   THROMBOSIS AND HAEMOSTASIS

The calcium-activated potassium channel KCa3.1 plays a central role in the chemotactic response of mammalian neutrophils

(2015) C. Henríquez et al.   Acta Physiologica

Ion Channels in Innate and Adaptive Immunity

(2015) Stefan Feske et al.   Annual Review of Immunology

Store-operated calcium signaling in neutrophils

(2015) R. A. Clemens et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion

(2015) Monika Pruenster et al.   Nature Communications

Kv1.3 in psoriatic disease: PAP-1, a small molecule inhibitor of Kv1.3 is effective in the SCID mouse psoriasis – Xenograft model

(2014) Smriti Kundu-Raychaudhuri et al.   JOURNAL OF AUTOIMMUNITY

Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade

(2014) E M Grössinger et al.   LEUKEMIA

Ontogenetic regulation of leukocyte recruitment in mouse yolk sac vessels

(2013) M. Sperandio et al.   BLOOD

Autoimmune effector memory T cells: the bad and the good

(2013) Priyadharshini Devarajan et al.   IMMUNOLOGIC RESEARCH

Neutrophil and endothelial adhesive function during human fetal ontogeny

(2012) C. Nussbaum et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The molecular basis of leukocyte recruitment and its deficiencies

(2012) Sarah Schmidt et al.   MOLECULAR IMMUNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Role of Ion Channels and Transporters in Cell Migration

(2012) Albrecht Schwab et al.   PHYSIOLOGICAL REVIEWS

Chemokines, selectins and intracellular calcium flux: temporal and spatial cues for leukocyte arrest

(2012) Neha Dixit et al.   Frontiers in Immunology

Migrational Guidance of Neutrophils Is Mechanotransduced via High-Affinity LFA-1 and Calcium Flux

(2011) N. Dixit et al.   JOURNAL OF IMMUNOLOGY

The role of calcium signaling in phagocytosis

(2010) Paula Nunes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cell migration to the chemokine CXCL8: Paxillin is activated and regulates adhesion and cell motility

(2009) E. Cohen-Hillel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The functional network of ion channels in T lymphocytes

(2009) Michael D. Cahalan et al.   IMMUNOLOGICAL REVIEWS

Integrins in immunity

(2009) R. Evans et al.   JOURNAL OF CELL SCIENCE

Calcium Flux in Neutrophils Synchronizes β2 Integrin Adhesive and Signaling Events that Guide Inflammatory Recruitment

(2008) Ulrich Y. Schaff et al.   ANNALS OF BIOMEDICAL ENGINEERING

Advances in Neutrophil Biology

(2008) Andrew S. Cowburn et al.   CHEST

Imaging of Effector Memory T Cells during a Delayed-Type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block

(2008) Melanie P. Matheu et al.   IMMUNITY

Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation

(2008) David Frommhold et al.   JOURNAL OF EXPERIMENTAL MEDICINE