Interferon regulatory factor 1(IRF-1) activates anti-tumor immunity via CXCL10/CXCR3 axis in hepatocellular carcinoma (HCC)

Tumor Immunology and Tumor Evolution: Intertwined Histories

(2020) Jérôme Galon et al.   IMMUNITY

Interferon regulatory factor 1 (IRF-1) and IRF-2 regulate PD-L1 expression in hepatocellular carcinoma (HCC) cells

(2020) Yihe Yan et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma

(2020) Richard S. Finn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Verteporfin Inhibits PD-L1 through Autophagy and the STAT1–IRF1–TRIM28 Signaling Axis, Exerting Antitumor Efficacy

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CXCR3 Ligands in Cancer and Autoimmunity, Chemoattraction of Effector T Cells, and Beyond

(2020) Nathan Karin   Frontiers in Immunology

Plasma Cell Polarization to the Immunoglobulin G Phenotype in Hepatocellular Carcinomas Involves Epigenetic Alterations and Promotes Hepatoma Progression in Mice

(2019) Yuan Wei et al.   GASTROENTEROLOGY

Micro RNA ‐223 ameliorates nonalcoholic steatohepatitis and cancer by targeting multiple inflammatory and oncogenic genes in hepatocytes

(2019) Yong He et al.   HEPATOLOGY

Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy

(2019) Melvyn T. Chow et al.   IMMUNITY

Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells

(2019) Tomoyuki Ohsugi et al.   ONCOGENE

Understanding and overcoming the resistance of cancer to PD-1/PD-L1 blockade

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IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell

(2019) Lulu Shao et al.   Cancer Immunology Research

Interferon-inducible lncRNA IRF1-AS represses esophageal squamous cell carcinoma by promoting interferon response

(2019) Jianbing Huang et al.   CANCER LETTERS

Targeted therapy for hepatocellular carcinoma: Challenges and opportunities

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Molecular targeted and immune checkpoint therapy for advanced hepatocellular carcinoma

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CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation – A target for novel cancer therapy

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XAF1 forms a positive feedback loop with IRF-1 to drive apoptotic stress response and suppress tumorigenesis

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The Role of CXC Chemokine Receptors 1–4 on Immune Cells in the Tumor Microenvironment

(2018) Katharina Helene Susek et al.   Frontiers in Immunology

PARP1 Suppresses the Transcription of PD-L1 by Poly(ADP-Ribosyl)ating STAT3

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Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses

(2017) Valerie Chew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer

(2016) Holger Bronger et al.   BRITISH JOURNAL OF CANCER

CXCL10/CXCR3 signaling mobilized-regulatory T cells promote liver tumor recurrence after transplantation

(2016) Chang Xian Li et al.   JOURNAL OF HEPATOLOGY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Chemokine (C-X-C motif) receptor 3-positive B cells link interleukin-17 inflammation to protumorigenic macrophage polarization in human hepatocellular carcinoma

(2015) Rui-Xian Liu et al.   HEPATOLOGY

IRF-1 Promotes Liver Transplant Ischemia/Reperfusion Injury via Hepatocyte IL-15/IL-15Rα Production

(2015) Shinichiro Yokota et al.   JOURNAL OF IMMUNOLOGY

CXCL10-induced migration of adoptively transferred human natural killer cells toward solid tumors causes regression of tumor growth in vivo

(2014) Erik Wennerberg et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti-PD-1 Therapy

(2014) J. M. Taube et al.   CLINICAL CANCER RESEARCH

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

(2014) Antonella Sistigu et al.   NATURE MEDICINE

Nitric Oxide Production Upregulates Wnt/ -Catenin Signaling by Inhibiting Dickkopf-1

(2013) Q. Du et al.   CANCER RESEARCH

Molecular Pathways: Hepatitis C Virus, CXCL10, and the Inflammatory Road to Liver Cancer

(2013) J. Brownell et al.   CLINICAL CANCER RESEARCH

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Interferon-gamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1)

(2011) Peiyuan Li et al.   CANCER LETTERS

Human Rhinovirus–Induced Epithelial Production of CXCL10 Is Dependent upon IFN Regulatory Factor-1

(2009) Raza S. Zaheer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism

(2009) B Cambien et al.   BRITISH JOURNAL OF CANCER

Critical role of interferon regulatory factor-1 in murine liver transplant ischemia reperfusion injury

(2009) Shinya Ueki et al.   HEPATOLOGY

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology