Analysis and optimal design of batch and two‐column continuous chromatographic frontal processes for monoclonal antibody purification

Process‐wide control and automation of an integrated continuous manufacturing platform for antibodies

(2020) Fabian Feidl et al.   BIOTECHNOLOGY AND BIOENGINEERING

Model-based process development of continuous chromatography for antibody capture: A case study with twin-column system

(2020) Ce Shi et al.   JOURNAL OF CHROMATOGRAPHY A

Design space and robustness analysis of batch and counter-current frontal chromatography processes for the removal of antibody aggregates

(2020) Sebastian Vogg et al.   JOURNAL OF CHROMATOGRAPHY A

Displacement to separate host‐cell proteins and aggregates in cation‐exchange chromatography of monoclonal antibodies

(2020) Ohnmar Khanal et al.   BIOTECHNOLOGY AND BIOENGINEERING

Cation exchange frontal chromatography for the removal of monoclonal antibody aggregates

(2019) Matthew T. Stone et al.   JOURNAL OF CHROMATOGRAPHY A

Continuous integrated manufacturing of therapeutic proteins

(2018) Daniel Johannes Karst et al.   CURRENT OPINION IN BIOTECHNOLOGY

Integrated flow-through purification for therapeutic monoclonal antibodies processing

(2018) Takamitsu Ichihara et al.   mAbs

The Increasingly Human and Profitable Monoclonal Antibody Market

(2018) António L. Grilo et al.   TRENDS IN BIOTECHNOLOGY

Current status and future challenges in continuous biochromatography

(2018) Sebastian Vogg et al.   Current Opinion in Chemical Engineering

Separation of antibody monomer-dimer mixtures by frontal analysis

(2017) Jason M. Reck et al.   JOURNAL OF CHROMATOGRAPHY A

Protein adsorption on ion exchange resins and monoclonal antibody charge variant modulation

(2016) Bertrand Guélat et al.   JOURNAL OF CHROMATOGRAPHY A

Optimal model-based design of the twin-column CaptureSMB process improves capacity utilization and productivity in protein A affinity capture

(2015) Daniel Baur et al.   Biotechnology Journal

Robustness of steady state recycling chromatography with an integrated solvent removal unit

(2015) Jani Siitonen et al.   JOURNAL OF CHROMATOGRAPHY A

Optimal model-based design of the twin-column CaptureSMB process improves capacity utilization and productivity in protein A affinity capture

(2015) Daniel Baur et al.   Biotechnology Journal

Model-Based Comparison of Batch and Continuous Preparative Chromatography in the Separation of Rare Earth Elements

(2014) Niklas Andersson et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Modeling multicomponent adsorption of monoclonal antibody charge variants in cation exchange columns

(2011) Yinying Tao et al.   AICHE JOURNAL

Model simulation and experimental verification of a cation-exchange IgG capture step in batch and continuous chromatography

(2011) T. Müller-Späth et al.   JOURNAL OF CHROMATOGRAPHY A

Overloading ion-exchange membranes as a purification step for monoclonal antibodies

(2010) Arick Brown et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Increasing the activity of monoclonal antibody therapeutics by continuous chromatography (MCSGP)

(2010) T. Müller-Späth et al.   BIOTECHNOLOGY AND BIOENGINEERING

Decision-Support Tool for Assessing Biomanufacturing Strategies under Uncertainty: Stainless Steel versus Disposable Equipment for Clinical Trial Material Preparation

(2005) Suzanne S. Farid et al.   BIOTECHNOLOGY PROGRESS