Targeted regulation of lymphocytic ER stress response with an overall immunosuppression to alleviate allograft rejection

A Vaccination with Boosted Cross Presentation by ER‐Targeted Antigen Delivery for Anti‐Tumor Immunotherapy

(2021) Yingying Shi et al.   Advanced Healthcare Materials

Virus-like Nonvirus Cationic Liposome for Efficient Gene Delivery via Endoplasmic Reticulum Pathway

(2020) Xiaoling Yuan et al.   ACS Central Science

Programmed T cell differentiation: Implications for transplantation

(2020) Rebecca L. Crepeau et al.   CELLULAR IMMUNOLOGY

CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes

(2020) Chikako Shimokawa et al.   Nature Communications

Appropriate Delivery of the CRISPR/Cas9 System through the Nonlysosomal Route: Application for Therapeutic Gene Editing

(2020) Hang Yin et al.   Advanced Science

Endoplasmic Reticulum Stress Contributes to Mitochondrial Exhaustion of CD8 T cells

(2019) Katie Hurst et al.   Cancer Immunology Research

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

(2019) Yu Cao et al.   Nature Communications

Adaptive endoplasmic reticulum stress signalling via IRE1α–XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells

(2019) Lu Liu et al.   NATURE CELL BIOLOGY

Antigen-specific therapeutic approaches for autoimmunity

(2019) Pau Serra et al.   NATURE BIOTECHNOLOGY

The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc

(2019) Han Dong et al.   NATURE IMMUNOLOGY

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors

(2019) Mohamed Mahameed et al.   Cell Death & Disease

Cytotoxic T-lymphocyte therapy for post-transplant lymphoproliferative disorder after solid organ transplantation in children

(2018) Fang Kuan Chiou et al.   PEDIATRIC TRANSPLANTATION

The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress

(2018) Justine Lebeau et al.   Cell Reports

CD8 + effector memory T cells induce acute rejection of allogeneic heart retransplants in mice possibly through activating expression of inflammatory cytokines

(2017) Gang Du et al.   EXPERIMENTAL CELL RESEARCH

Immune Tolerance for Autoimmune Disease and Cell Transplantation

(2016) Xunrong Luo et al.   Annual Review of Biomedical Engineering

The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells

(2016) Ana Sofia Martins et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

NOD1 and NOD2 signalling links ER stress with inflammation

(2016) A. Marijke Keestra-Gounder et al.   NATURE

Allorecognition by T Lymphocytes and Allograft Rejection

(2016) Jose Marino et al.   Frontiers in Immunology

Emerging Therapies Targeting Intra-Organ Inflammation in Transplantation

(2015) Z. Solhjou et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies

(2015) Young Joo Jeon et al.   CANCER CELL

ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

(2015) Juan R. Cubillos-Ruiz et al.   CELL

Acid-induced autophagy protects human lung cancer cells from apoptosis by activating ER stress

(2015) Wen-Yue Xie et al.   EXPERIMENTAL CELL RESEARCH

Cleavage ofBLOC1S1mRNA by IRE1 Is Sequence Specific, Temporally Separate fromXBP1Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress

(2015) Michael D. Bright et al.   MOLECULAR AND CELLULAR BIOLOGY

BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

(2015) Frederik Otzen Bagger et al.   NUCLEIC ACIDS RESEARCH

CD8 T-cell recognition of acquired alloantigen promotes acute allograft rejection

(2015) Simon J. F. Harper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Memory T Cells and Perspectives for Intervention in Organ Transplantation

(2015) Kailin Lin et al.   Frontiers in Immunology

FK506-Binding Proteins and Their Diverse Functions

(2015) Mingming Tong et al.   Current Molecular Pharmacology

Bcl-2 Inhibition to Overcome Memory Cell Barriers in Transplantation

(2014) P. E. Cippà et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Endogenous Memory CD8 T Cells Directly Mediate Cardiac Allograft Rejection

(2014) C. A. Su et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress

(2014) Rajarshi Ghosh et al.   CELL

Calcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functions

(2014) Alain Vandewalle et al.   Cell Communication and Signaling

Location and Time-Dependent Control of Rejection by Regulatory T Cells Culminates in a Failure to Generate Memory T Cells

(2014) M. Carvalho-Gaspar et al.   JOURNAL OF IMMUNOLOGY

Emerging functions of the unfolded protein response in immunity

(2014) Sophie Janssens et al.   NATURE IMMUNOLOGY

Induction of suppressive allogeneic regulatory T cells via rabbit antithymocyte polyclonal globulin during homeostatic proliferation in rat kidney transplantation

(2014) Rafael Valdez-Ortiz et al.   TRANSPLANT INTERNATIONAL

Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation

(2013) J Adam Best et al.   NATURE IMMUNOLOGY

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

(2012) Alana G. Lerner et al.   Cell Metabolism

Immune recognition and rejection of allogeneic skin grafts

(2011) Gilles Benichou et al.   Immunotherapy

Transcriptomes of the B and T Lineages Compared by Multiplatform Microarray Profiling

(2011) M. W. Painter et al.   JOURNAL OF IMMUNOLOGY

Functional Analysis of Alloreactive Memory CD4+ T Cells Derived from Skin Transplantation Recipient and Naïve CD4+ T Cells Derived from Untreated Mice

(2011) Lei Luo et al.   JOURNAL OF SURGICAL RESEARCH

The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α

(2011) Claudio Hetz et al.   PHYSIOLOGICAL REVIEWS

Suppressing memory T cell activation induces islet allograft tolerance in alloantigen-primed mice

(2010) Junjie Xia et al.   TRANSPLANT INTERNATIONAL

Kidney Transplantation as Primary Therapy for End-Stage Renal Disease: A National Kidney Foundation/Kidney Disease Outcomes Quality Initiative (NKF/KDOQITM) Conference

(2008) M. Abecassis et al.   Clinical Journal of the American Society of Nephrology

B- and T-cell Development Both Involve Activity of the Unfolded Protein Response Pathway

(2008) Ryan Brunsing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY