Differential analysis of genome-wide methylation and gene expression in mesenchymal stem cells of patients with fractures and osteoarthritis

Shared genetic control of expression and methylation in peripheral blood

(2016) Konstantin Shakhbazov et al.   BMC GENOMICS

Genome-wide DNA methylation profile implicates potential cartilage regeneration at the late stage of knee osteoarthritis

(2016) Y. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

In vitro characterization of bone marrow stromal cells from osteoarthritic donors

(2016) Maik Stiehler et al.   Stem Cell Research

Systemic Mesenchymal Stromal Cell Transplantation Prevents Functional Bone Loss in a Mouse Model of Age-Related Osteoporosis

(2016) Jeffrey Kiernan et al.   Stem Cells Translational Medicine

Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage

(2016) Matlock A. Jeffries et al.   Arthritis & Rheumatology

The p53/miR-17/Smurf1 pathway mediates skeletal deformities in an age-related model via inhibiting the function of mesenchymal stem cells

(2015) Wenjia Liu et al.   Aging-US

Targeted delivery of mesenchymal stem cells to the bone

(2015) Wei Yao et al.   BONE

Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women

(2015) Matthew M. Roforth et al.   BONE

Epigenetic Mechanisms Regulating Mesenchymal Stem Cell Differentiation

(2015) Flor Perez-Campo et al.   CURRENT GENOMICS

Mesenchymal stem cell aging: Mechanisms and influences on skeletal and non-skeletal tissues

(2015) Huijuan Liu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B

(2015) Adriana Rojas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoporosis-associated alteration in the signalling status of BMP-2 in human MSCs under adipogenic conditions

(2015) Oscar Donoso et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Exposure to a youthful circulation rejuvenates bone repair through modulation of β-catenin

(2015) Gurpreet S. Baht et al.   Nature Communications

Mesenchymal stem cells from osteoporotic patients reveal reduced migration and invasion upon stimulation with BMP-2 or BMP-7

(2014) Florian Haasters et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Comprehensive analysis of DNA methylation data with RnBeads

(2014) Yassen Assenov et al.   NATURE METHODS

Stem Cell Therapy for Osteoporosis

(2014) Ben Antebi et al.   Current Osteoporosis Reports

Mesenchymal stem cells from osteoporotic patients feature impaired signal transduction but sustained osteoinduction in response to BMP-2 stimulation

(2013) Wolf Christian Prall et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Redefining the activity of a bone-specific transcription factor: Novel insights for understanding bone formation

(2013) Jane B Lian et al.   JOURNAL OF BONE AND MINERAL RESEARCH

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes

(2013) Guangyi Li et al.   ARTHRITIS RESEARCH & THERAPY

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice

(2013) Kevin A. Maupin et al.   Bone Research

Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis

(2012) Jesús Delgado-Calle et al.   ARTHRITIS AND RHEUMATISM

Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects

(2012) Kristel R van Eijk et al.   BMC GENOMICS

The effects of an injury to the brain on bone healing and callus formation in young adults with fractures of the femoral shaft

(2012) T-Y. Yang et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineage

(2011) Jesús Delgado-Calle et al.   BONE

DNA methylation contributes to the regulation of sclerostin expression in human osteocytes

(2011) Jesús Delgado-Calle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Circulating plastic adherent mesenchymal stem cells in aged hip fracture patients

(2010) Jessica J. Alm et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

AltAnalyze and DomainGraph: analyzing and visualizing exon expression data

(2010) Dorothea Emig et al.   NUCLEIC ACIDS RESEARCH

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma

(2007) Ya-Wei Qiang et al.   BONE