Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes

Medial femoral condyle morphometrics and subchondral bone density patterns in Thoroughbred racehorses

(2013) Wade T. Walker et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

In Obese Postmenopausal Women, Bone Microarchitecture and Strength Are Not Commensurate to Greater Body Weight: The Os des Femmes de Lyon (OFELY) Study

(2013) Elisabeth Sornay-Rendu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Relationship between microstructure and degree of mineralization in subchondral bone of osteoarthritis: A synchrotron radiation µCT study

(2012) Ko Chiba et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone remodelling in osteoarthritis

(2012) David B. Burr et al.   Nature Reviews Rheumatology

Bone and cartilage demonstrate changes localized to bone marrow edema-like lesions within osteoarthritic knees

(2012) G.J. Kazakia et al.   OSTEOARTHRITIS AND CARTILAGE

Subchondral bone and osteoarthritis: biological and cellular aspects

(2012) Y. Henrotin et al.   OSTEOPOROSIS INTERNATIONAL

An in vivo investigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritis

(2012) David D McErlain et al.   ARTHRITIS RESEARCH & THERAPY

Alterations in periarticular bone and cross talk between subchondral bone and articular cartilage in osteoarthritis

(2012) Steven R. Goldring   Therapeutic Advances in Musculoskeletal Disease

Subchondral bone as a key target for osteoarthritis treatment

(2011) Santos Castañeda et al.   BIOCHEMICAL PHARMACOLOGY

Genetic factors in OA pathogenesis

(2011) Kay Chapman et al.   BONE

Osteochondral alterations in osteoarthritis

(2011) Sunita Suri et al.   BONE

Biomechanical considerations in the pathogenesis of osteoarthritis of the knee

(2011) Andras Heijink et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury

(2011) Robert A Mooney et al.   ARTHRITIS RESEARCH & THERAPY

Effects of obesity on bone metabolism

(2011) Jay J Cao   Journal of Orthopaedic Surgery and Research

Mechanical loading, cartilage degradation, and arthritis

(2010) Hui B. Sun   Annals of the New York Academy of Sciences

Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis

(2010) Mary B. Goldring et al.   Annals of the New York Academy of Sciences

Why is osteoarthritis an age-related disease?

(2010) A. Shane Anderson et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Activation of bone remodeling after fatigue: Differential response to linear microcracks and diffuse damage

(2010) B.C. Herman et al.   BONE

Relationship between joint shape and the development of osteoarthritis

(2010) Julie C Baker-LePain et al.   CURRENT OPINION IN RHEUMATOLOGY

The basic science of the subchondral bone

(2010) Henning Madry et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

In early OA, thinning of the subchondral plate is directly related to cartilage damage: results from a canine ACLT-meniscectomy model

(2010) F. Intema et al.   OSTEOARTHRITIS AND CARTILAGE

Longitudinal assessment of bone marrow edema-like lesions and cartilage degeneration in osteoarthritis using 3 T MR T1rho quantification

(2010) Jian Zhao et al.   SKELETAL RADIOLOGY

Estrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

(2010) Yvonne H Sniekers et al.   ARTHRITIS RESEARCH & THERAPY

Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis

(2010) Miriam Bellido et al.   ARTHRITIS RESEARCH & THERAPY

The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study

(2010) Stephanie K Tanamas et al.   ARTHRITIS RESEARCH & THERAPY

Subchondral bone attrition may be a reflection of compartment-specific mechanical load: the MOST Study

(2009) T. Neogi et al.   ANNALS OF THE RHEUMATIC DISEASES

Employing molecular genetics of chondrodysplasias to inform the study of osteoarthritis

(2009) Peter Kannu et al.   ARTHRITIS AND RHEUMATISM

Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen

(2009) Kyle D. Allen et al.   ARTHRITIS AND RHEUMATISM

Bone mass and geometry of the tibia and the radius of master sprinters, middle and long distance runners, race-walkers and sedentary control participants: A pQCT study

(2009) D.C. Wilks et al.   BONE

In situ measurement of transport between subchondral bone and articular cartilage

(2009) Jun Pan et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Primary Osteoarthritis No Longer Primary: Three Subsets with Distinct Etiological, Clinical, and Therapeutic Characteristics

(2009) Gabriel Herrero-Beaumont et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized

(2009) David J Hunter et al.   ARTHRITIS RESEARCH & THERAPY

Tibiofemoral Contact Pressures and Osteochondral Microtrauma during Anterior Cruciate Ligament Rupture Due to Excessive Compressive Loading and Internal Torque of the Human Knee

(2008) Eric G. Meyer et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Association of bone scintigraphic abnormalities with knee malalignment and pain

(2008) V B Kraus et al.   ANNALS OF THE RHEUMATIC DISEASES

Bone marrow lesions predict increase in knee cartilage defects and loss of cartilage volume in middle-aged women without knee pain over 2 years

(2008) A E Wluka et al.   ANNALS OF THE RHEUMATIC DISEASES

Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort study

(2008) L S Lohmander et al.   ANNALS OF THE RHEUMATIC DISEASES

Obesity and osteoarthritis in knee, hip and/or hand: An epidemiological study in the general population with 10 years follow-up

(2008) Margreth Grotle et al.   BMC MUSCULOSKELETAL DISORDERS

Changes in subchondral bone mineral density and collagen matrix organization in growing horses☆☆Sources of funding: Financial support was received from the Ministry of Education in Finland (projects 25/627/2006 and 61/627/2005), Academy of Finland (projects 113112, 213548, and 216231), the National Graduate School of Musculo-Skeletal Diseases in Finland and the North-Savo Fund of the Finnish Cultural Foundation. The GEXA study is a project by the Global Equine Research Alliance for which the financial support was granted by the Marilyn Simpson Trust (USA), Horserace Betting Levy Board (UK), Utrecht University (The Netherlands) and the New Zealand Racing Board.

(2008) Jaakko T. Holopainen et al.   BONE

Etiopathogenesis of Osteoarthritis

(2008) Kenneth D. Brandt et al.   MEDICAL CLINICS OF NORTH AMERICA

Role of Bone in Osteoarthritis Pathogenesis

(2008) Steven R. Goldring   MEDICAL CLINICS OF NORTH AMERICA

Should subchondral bone turnover be targeted when treating osteoarthritis?

(2008) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

Animal models for osteoarthritis: the effect of ovariectomy and estrogen treatment – a systematic approach

(2008) Y.H. Sniekers et al.   OSTEOARTHRITIS AND CARTILAGE

Meniscal damage associated with increased local subchondral bone mineral density: a Framingham study

(2007) G.H. Lo et al.   OSTEOARTHRITIS AND CARTILAGE