Novel roles of Tsukushi in signaling pathways and multiple disease processes

Tsukushi is essential for proper maintenance and terminal differentiation of mouse hippocampal neural stem cells

(2020) Shah Adil Ishtiyaq Ahmad et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Correction to: FoxD1-driven CCN2 deletion causes axial skeletal deformities, pulmonary hypoplasia, and neonatal asphyctic death

(2020) Lucas L. Falke et al.   Journal of Cell Communication and Signaling

Significance of Tsukushi in lung cancer

(2019) Tatsuya Yamada et al.   LUNG CANCER

Podocan Promotes Differentiation of Bovine Skeletal Muscle Satellite Cells by Regulating the Wnt4-β-Catenin Signaling Pathway

(2019) Shuang Li et al.   Frontiers in Physiology

Recent advances in the use of microcarriers for cell cultures and their ex vivo and in vivo applications

(2019) Xiao-Yi Chen et al.   BIOTECHNOLOGY LETTERS

Biglycan regulates neuroinflammation by promoting M1 microglial activation in early brain injury after experimental subarachnoid hemorrhage

(2019) Yuke Xie et al.   JOURNAL OF NEUROCHEMISTRY

Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway

(2019) Tao Xu et al.   OncoTargets and Therapy

The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis

(2019) Mathilde Mouchiroud et al.   Molecular Metabolism

Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells

(2019) Stefan Salcher et al.   Cells

Collective transcriptomic deregulation of hypertrophic and dilated cardiomyopathy – Importance of fibrotic mechanism in heart failure

(2018) Beutline Malgija et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Association of SLRPs with carotid artery atherosclerosis in essential hypertensive patients

(2018) Yan Yang et al.   JOURNAL OF HUMAN HYPERTENSION

Biglycan-mediated upregulation of MHC class I expression in HER-2/neu-transformed cells

(2018) Karthikeyan Subbarayan et al.   OncoImmunology

CCN2/CTGF binds the small leucine rich proteoglycan protein Tsukushi

(2018) Kunimasa Ohta et al.   Journal of Cell Communication and Signaling

microRNA-2110 functions as an onco-suppressor in neuroblastoma by directly targeting Tsukushi

(2018) Zhenze Zhao et al.   PLoS One

Small leucine rich proteoglycans in host immunity and renal diseases

(2018) Wei Zou et al.   Journal of Cell Communication and Signaling

Mapping the molecular signatures of diet-induced NASH and its regulation by the hepatokine Tsukushi

(2018) Xuelian Xiong et al.   Molecular Metabolism

Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants

(2017) Louise Hsieh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of Tsukushi (TSK), a small leucine-rich repeat proteoglycan, in bone growth

(2017) Kosei Yano et al.   Regenerative Therapy

Small leucine rich proteoglycans, a novel link to osteoclastogenesis

(2017) Vardit Kram et al.   Scientific Reports

Steroid and xenobiotic receptor-mediated effects of bisphenol A on human osteoblasts

(2016) Yasuhiro Miki et al.   LIFE SCIENCES

Tsukushi expression is dependent on Notch signaling and oscillated in the presomitic mesoderm during chick somitogenesis

(2015) Uzzal Kumar Acharjee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury

(2014) Kristin Moreth et al.   MATRIX BIOLOGY

Tsukushi is involved in the wound healing by regulating the expression of cytokines and growth factors

(2014) Daisuke Niimori et al.   Journal of Cell Communication and Signaling

Biological interplay between proteoglycans and their innate immune receptors in inflammation

(2013) Helena Frey et al.   FEBS Journal

Small leucine rich proteoglycan family regulates multiple signalling pathways in neural development and maintenance

(2012) Margaret Dellett et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Tsukushi controls the hair cycle by regulating TGF-β1 signaling

(2012) Daisuke Niimori et al.   DEVELOPMENTAL BIOLOGY

The combinatorial guidance activities of draxin and Tsukushi are essential for forebrain commissure formation

(2012) Mahmud Hossain et al.   DEVELOPMENTAL BIOLOGY

Stromal Expression of Decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in Developing Prostate and Decreased Levels of Decorin in Prostate Cancer

(2012) Alexander Henke et al.   PLoS One

Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled4

(2011) K. Ohta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tsukushi is required for anterior commissure formation in mouse brain

(2010) Ayako Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

(2010) Kristin Moreth et al.   JOURNAL OF CLINICAL INVESTIGATION

Decorin is a secreted protein associated with obesity and type 2 diabetes

(2008) K Bolton et al.   INTERNATIONAL JOURNAL OF OBESITY

Biological Functions of the Small Leucine-rich Proteoglycans: From Genetics to Signal Transduction

(2008) Liliana Schaefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY