Formononetin protects against concanavalin-A-induced autoimmune hepatitis in mice through its anti-apoptotic and anti-inflammatory properties

Genistein can ameliorate hepatic inflammatory reaction in nonalcoholic steatohepatitis rats

(2019) Yimin Yin et al.   BIOMEDICINE & PHARMACOTHERAPY

Formononetin ameliorates cholestasis by regulating hepatic SIRT1 and PPARα

(2019) Shu Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Formononetin alleviates hepatic steatosis by facilitating TFEB-mediated lysosome biogenesis and lipophagy

(2019) Yan Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Formononetin inhibits neuroinflammation and increases estrogen receptor beta (ERβ) protein expression in BV2 microglia

(2018) Abdelmeniem El-Bakoush et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

NOD-Like Receptor Protein 3 Inflammasome-Dependent IL-1β Accelerated ConA-Induced Hepatitis

(2018) Jingyun Luan et al.   Frontiers in Immunology

Quantitative Proteomic Analysis Reveals That Arctigenin Alleviates Concanavalin A-Induced Hepatitis Through Suppressing Immune System and Regulating Autophagy

(2018) Qin Feng et al.   Frontiers in Immunology

Formononetin and biochanin A protects against ritonavir induced hepatotoxicity via modulation of NfκB/pAkt signaling molecules

(2018) Alauddin et al.   LIFE SCIENCES

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

(2017) Auvro R. Mridha et al.   JOURNAL OF HEPATOLOGY

Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome

(2017) Zhengwang Cao et al.   JOURNAL OF PINEAL RESEARCH

Targeting Oct2 and P53: Formononetin prevents cisplatin-induced acute kidney injury

(2017) Di Huang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Formononetin ameliorates mast cell‑mediated allergic inflammation via inhibition of histamine release and production of pro‑inflammatory cytokines

(2017) Ning Xu et al.   Experimental and Therapeutic Medicine

Formononetin protects against acetaminophen-induced hepatotoxicity through enhanced NRF2 activity

(2017) Fen Jin et al.   PLoS One

Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury in mice by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation

(2016) Xingkai Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Protective Effects of Genistein and Puerarin against Chronic Alcohol-Induced Liver Injury in Mice via Antioxidant, Anti-inflammatory, and Anti-apoptotic Mechanisms

(2016) Liang Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

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Mechanism of NLRP3 inflammasome activation

(2014) Fayyaz S. Sutterwala et al.   Annals of the New York Academy of Sciences

Formononetin mediates neuroprotection against cerebral ischemia/reperfusion in rats via downregulation of the Bax/Bcl-2 ratio and upregulation PI3K/Akt signaling pathway

(2014) Kun Liang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Formononetin potentiates epirubicin-induced apoptosis via ROS production in HeLa cells in vitro

(2013) Yu-Li Lo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1

(2013) Seok-Joo Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Cardioprotective Effect of Sulphonated Formononetin on Acute Myocardial Infarction in Rats

(2011) Shumin Zhang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Interleukin-17 Contributes to the Pathogenesis of Autoimmune Hepatitis through Inducing Hepatic Interleukin-6 Expression

(2011) Li Zhao et al.   PLoS One

Advances in the Diagnosis, Pathogenesis, and Management of Autoimmune Hepatitis

(2010) Albert J. Czaja et al.   GASTROENTEROLOGY

Apoptosis as a Mechanism for Liver Disease Progression

(2010) Maria Eugenia Guicciardi et al.   SEMINARS IN LIVER DISEASE

Aetiopathogenesis of autoimmune hepatitis

(2009) Maria Serena Longhi et al.   JOURNAL OF AUTOIMMUNITY

NF-κB signaling, liver disease and hepatoprotective agents

(2008) B Sun et al.   ONCOGENE

Aetiopathogenesis of autoimmune hepatitis

(2008) Diego Vergani et al.   WORLD JOURNAL OF GASTROENTEROLOGY