Rubicon regulates A2E-induced autophagy impairment in the retinal pigment epithelium implicated in the pathology of age-related macular degeneration

Suppression of autophagic activity by Rubicon is a signature of aging

(2019) Shuhei Nakamura et al.   Nature Communications

Accurate Estimation of the Standard Binding Free Energy of Netropsin with DNA

(2018) Hong Zhang et al.   MOLECULES

Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice

(2016) Satoshi Tanaka et al.   HEPATOLOGY

Autophagy in the eye: Development, degeneration, and aging

(2016) Patricia Boya et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Deletion of autophagy inducerRB1CC1results in degeneration of the retinal pigment epithelium

(2015) Jingyu Yao et al.   Autophagy

NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration

(2015) Jiangyuan Gao et al.   MEDIATORS OF INFLAMMATION

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

Prevention of Age-Related Macular Degeneration–Like Retinopathy by Rapamycin in Rats

(2012) Nataliya G. Kolosova et al.   AMERICAN JOURNAL OF PATHOLOGY

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration

(2012) M. Suzuki et al.   JOURNAL OF CELL SCIENCE

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells

(2009) Shozo Sonoda et al.   Nature Protocols

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE