Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression

Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

(2020) Ping-Pui Wong et al.   CELL

Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth

(2020) Tanguy Lechertier et al.   Nature Communications

High levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the serum are associated with poor prognosis in HPV-negative squamous cell oropharyngeal cancer

(2019) Timo Carpén et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861

(2019) Ana-Rita Pedrosa et al.   CANCER RESEARCH

Tumor Angiogenic Inhibition Triggered Necrosis (TAITN) in Oral Cancer

(2019) Saori Yoshida et al.   Cells

Dual role of pericyte α6β1-integrin in tumour blood vessels

(2017) Louise E. Reynolds et al.   JOURNAL OF CELL SCIENCE

Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents

(2017) Minfeng Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium-specific FAK-kinase dead mice

(2017) Annika N Alexopoulou et al.   JOURNAL OF PATHOLOGY

KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis

(2017) Meera Murgai et al.   NATURE MEDICINE

CD146 coordinates brain endothelial cell–pericyte communication for blood–brain barrier development

(2017) Jianan Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endosialin-Expressing Pericytes Promote Metastatic Dissemination

(2016) Carmen Viski et al.   CANCER RESEARCH

Angiocrine Factors Deployed by Tumor Vascular Niche Induce B Cell Lymphoma Invasiveness and Chemoresistance

(2014) Zhongwei Cao et al.   CANCER CELL

Generation of point-mutant FAK knockin mice

(2014) B. Tavora et al.   GENESIS

Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy

(2014) Bernardo Tavora et al.   NATURE

Pericyte-endothelial crosstalk: implications and opportunities for advanced cellular therapies

(2014) Anita Geevarghese et al.   Translational Research

Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes

(2013) J. Ruan et al.   BLOOD

Soluble ICAM-1 secretion and its functional role as an autocrine growth factor in nasal NK/T cell lymphoma cells

(2013) Miki Takahara et al.   EXPERIMENTAL HEMATOLOGY

A role for CCL2 in both tumor progression and immunosurveillance

(2013) Ming Li et al.   OncoImmunology

Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes

(2012) Marco Beauséjour et al.   APOPTOSIS

Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway

(2012) Vesselina G. Cooke et al.   CANCER CELL

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Overexpression of focal adhesion kinase correlates with increased lymph node metastasis and poor prognosis in non-small-cell lung cancer

(2012) Hong-Fei Ji et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

A novel and simple method for culturing pericytes from mouse brain

(2012) Ulrich Tigges et al.   MICROVASCULAR RESEARCH

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Angiogenesis Induced by Signal Transducer and Activator of Transcription 5A (STAT5A) Is Dependent on Autocrine Activity of Proliferin

(2011) Xinhai Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Focal adhesion kinase and tumour angiogenesis

(2011) Tanguy Lechertier et al.   JOURNAL OF PATHOLOGY

Endothelial Cell-Pericyte Interactions Stimulate Basement Membrane Matrix Assembly: Influence on Vascular Tube Remodeling, Maturation, and Stabilization

(2011) Amber N. Stratman et al.   MICROSCOPY AND MICROANALYSIS

Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment

(2011) J. B. Stokes et al.   MOLECULAR CANCER THERAPEUTICS

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling

(2011) Emma Sandilands et al.   NATURE CELL BIOLOGY

Use of the mouse aortic ring assay to study angiogenesis

(2011) Marianne Baker et al.   Nature Protocols

MCP-1 promotes mural cell recruitment during angiogenesis in the aortic ring model

(2010) Alfred C. Aplin et al.   ANGIOGENESIS

Conditional Deletion of the Focal Adhesion Kinase FAK Alters Remodeling of the Blood-Brain Barrier in Glioma

(2010) J. Lee et al.   CANCER RESEARCH

DNA Damage-Mediated Induction of a Chemoresistant Niche

(2010) Luke A. Gilbert et al.   CELL

Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse

(2010) Feng-Ju Huang et al.   DEVELOPMENTAL BIOLOGY

Endothelial FAK is required for tumour angiogenesis

(2010) Bernardo Tavora et al.   EMBO Molecular Medicine

Knock-in Mutation Reveals an Essential Role for Focal Adhesion Kinase Activity in Blood Vessel Morphogenesis and Cell Motility-Polarity but Not Cell Proliferation

(2010) Ssang-Taek Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Autophosphorylation-independent and -dependent Functions of Focal Adhesion Kinase during Development

(2009) Jean-Marc Corsi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271

(2008) W. G. Roberts et al.   CANCER RESEARCH