Directional Cues in the Tumor Microenvironment due to Cell Contraction against Aligned Collagen Fibers

Spatiotemporal force and motion in collective cell migration

(2020) Aashrith Saraswathibhatla et al.   Scientific Data

Modulus of Fibrous Collagen at the Length Scale of a Cell

(2019) M. Proestaki et al.   EXPERIMENTAL MECHANICS

The Extracellular Matrix Modulates the Metastatic Journey

(2019) FuiBoon Kai et al.   DEVELOPMENTAL CELL

The Presence of Cyclooxygenase 2, Tumor-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive Breast Carcinoma Patients

(2018) Karla Esbona et al.   AMERICAN JOURNAL OF PATHOLOGY

Intravital microscopy of collective invasion plasticity in breast cancer

(2018) Olga Ilina et al.   Disease Models & Mechanisms

Dynamics of 3D carcinoma cell invasion into aligned collagen

(2018) Arja Ray et al.   Integrative Biology

A Unidirectional Transition from Migratory to Perivascular Macrophage Is Required for Tumor Cell Intravasation

(2018) Esther N. Arwert et al.   Cell Reports

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

(2018) Lucas A. Tomko et al.   Scientific Reports

Mechanical response of collagen networks to nonuniform microscale loads

(2017) Brian Burkel et al.   Soft Matter

Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration

(2017) Arja Ray et al.   Nature Communications

Tumor Cell Invasion Can Be Blocked by Modulators of Collagen Fibril Alignment That Control Assembly of the Extracellular Matrix

(2016) Moran Grossman et al.   CANCER RESEARCH

Mechanosensing via cell-matrix adhesions in 3D microenvironments

(2016) Andrew D. Doyle et al.   EXPERIMENTAL CELL RESEARCH

Local extracellular matrix alignment directs cellular protrusion dynamics and migration through Rac1 and FAK

(2016) Shawn P. Carey et al.   Integrative Biology

Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway

(2016) E Leung et al.   ONCOGENE

In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging

(2016) Joseph M. Szulczewski et al.   Scientific Reports

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Microbuckling of fibrin provides a mechanism for cell mechanosensing

(2015) Jacob Notbohm et al.   Journal of the Royal Society Interface

Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions

(2015) Andrew D. Doyle et al.   Nature Communications

Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions

(2015) Stephanie I. Fraley et al.   Scientific Reports

3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

(2014) Kristin M. Riching et al.   BIOPHYSICAL JOURNAL

A Fast Iterative Digital Volume Correlation Algorithm for Large Deformations

(2014) E. Bar-Kochba et al.   EXPERIMENTAL MECHANICS

Computational segmentation of collagen fibers from second-harmonic generation images of breast cancer

(2014) Jeremy S. Bredfeldt et al.   JOURNAL OF BIOMEDICAL OPTICS

Matrix Microarchitecture and Myosin II Determine Adhesion in 3D Matrices

(2013) Kristopher E. Kubow et al.   CURRENT BIOLOGY

Strain stiffening in collagen I networks

(2012) Stéphanie Motte et al.   BIOPOLYMERS

Preparation and characterization of polyacrylamide nanomicrospheres and its profile control and flooding performance

(2012) Chuanjin Yao et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness

(2012) Jessica N. Heck et al.   MOLECULAR BIOLOGY OF THE CELL

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Filamin A–β1 Integrin Complex Tunes Epithelial Cell Response to Matrix Tension

(2009) Scott Gehler et al.   MOLECULAR BIOLOGY OF THE CELL

Non-Linear Elasticity of Extracellular Matrices Enables Contractile Cells to Communicate Local Position and Orientation

(2009) Jessamine P. Winer et al.   PLoS One

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL