Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway

In Vivo Visualization and Characterization of Epithelial–Mesenchymal Transition in Breast Tumors

(2016) Zhen Zhao et al.   CANCER RESEARCH

3-D individual cell based computational modeling of tumor cell–macrophage paracrine signaling mediated by EGF and CSF-1 gradients

(2016) Hildur Knutsdottir et al.   Integrative Biology

Menacalc, a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer

(2015) Catherine L. Forse et al.   BMC CANCER

Abstract A53: The specific FMS kinase inhibitor, DCC-3014, durably inhibits FMS kinase in vivo and blocks cancer bone invasiveness

(2015) Bryan D. Smith et al.   CANCER RESEARCH

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

(2015) Shannon K. Hughes et al.   MOLECULAR BIOLOGY OF THE CELL

Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2

(2015) B. D. Smith et al.   MOLECULAR CANCER THERAPEUTICS

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA

(2015) A. S. Harney et al.   Cancer Discovery

Metastatic breast cancer: mechanisms and opportunities for cytology

(2014) D. Martins et al.   CYTOPATHOLOGY

Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cells

(2014) A Patsialou et al.   ONCOGENE

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration

(2014) J. Pignatelli et al.   Science Signaling

Multiparametric Classification Links Tumor Microenvironments with Tumor Cell Phenotype

(2014) Bojana Gligorijevic et al.   PLOS BIOLOGY

Functions of cofilin in cell locomotion and invasion

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Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates

(2012) Ted Underiner et al.   Anti-Cancer Agents in Medicinal Chemistry

Single circulating tumor cell profiling: a new perspective for targeted therapy?

(2012) MC Cassatella et al.   Future Oncology

Mena binds α5 integrin directly and modulates α5β1 function

(2012) Stephanie L. Gupton et al.   JOURNAL OF CELL BIOLOGY

Correlated Immunohistochemical and Cytological Assays for the Prediction of Hematogenous Dissemination of Breast Cancer

(2012) Maja H. Oktay et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Breast Cancer

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Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036

(2011) Wayne W. Chan et al.   CANCER CELL

Mena invasive (MenaINV) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM

(2011) Evanthia T. Roussos et al.   CLINICAL & EXPERIMENTAL METASTASIS

Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer

(2011) E. T. Roussos et al.   JOURNAL OF CELL SCIENCE

Setup and use of a two-laser multiphoton microscope for multichannel intravital fluorescence imaging

(2011) David Entenberg et al.   Nature Protocols

Cytokine Receptor CXCR4 Mediates Estrogen-Independent Tumorigenesis, Metastasis, and Resistance to Endocrine Therapy in Human Breast Cancer

(2010) Lyndsay V. Rhodes et al.   CANCER RESEARCH

AACR Centennial Series: The Biology of Cancer Metastasis: Historical Perspective

(2010) J. E. Talmadge et al.   CANCER RESEARCH

Enzymatic Characterization of c-Met Receptor Tyrosine Kinase Oncogenic Mutants and Kinetic Studies with Aminopyridine and Triazolopyrazine Inhibitors

(2009) Sergei L. Timofeevski et al.   BIOCHEMISTRY

The EGF/CSF-1 Paracrine Invasion Loop Can Be Triggered by Heregulin  1 and CXCL12

(2009) L. Hernandez et al.   CANCER RESEARCH

Invasion of Human Breast Cancer Cells In vivo Requires Both Paracrine and Autocrine Loops Involving the Colony-Stimulating Factor-1 Receptor

(2009) A. Patsialou et al.   CANCER RESEARCH

Novel Therapeutic Inhibitors of the c-Met Signaling Pathway in Cancer

(2009) J. P. Eder et al.   CLINICAL CANCER RESEARCH

Tumor Microenvironment of Metastasis in Human Breast Carcinoma: A Potential Prognostic Marker Linked to Hematogenous Dissemination

(2009) B. D. Robinson et al.   CLINICAL CANCER RESEARCH

Collective cell migration in morphogenesis, regeneration and cancer

(2009) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells

(2009) Vera DesMarais et al.   CELL MOTILITY AND THE CYTOSKELETON

Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo

(2008) Sumanta Goswami et al.   CLINICAL & EXPERIMENTAL METASTASIS

A Mena Invasion Isoform Potentiates EGF-Induced Carcinoma Cell Invasion and Metastasis

(2008) Ulrike Philippar et al.   DEVELOPMENTAL CELL

Intravital imaging of metastatic behavior through a mammary imaging window

(2008) Dmitriy Kedrin et al.   NATURE METHODS