Loss of the exocyst complex component EXOC3 promotes hemostasis and accelerates arterial thrombosis

Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis

(2019) Shifeng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse Platelet Ral GTPases Control P-Selectin Surface Expression, Regulating Platelet–Leukocyte InteractionHighlights

(2018) Andreas Wersäll et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Downregulation of exocyst Sec10 accelerates kidney tubule cell recovery through enhanced cell migration

(2018) Mi Ra Noh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cryo-EM structure of the exocyst complex

(2018) Kunrong Mei et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure of the exocyst complex

(2018) Kunrong Mei et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss of the mitochondrial kinase PINK1 does not alter platelet function

(2018) Tony G. Walsh et al.   Scientific Reports

Exocyst dynamics during vesicle tethering and fusion

(2018) Syed Mukhtar Ahmed et al.   Nature Communications

Genetic compensation: A phenomenon in search of mechanisms

(2017) Mohamed A. El-Brolosy et al.   PLoS Genetics

Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition

(2016) Florian Beck et al.   BLOOD

Storage pool diseases illuminate platelet dense granule biogenesis

(2016) Andrea L. Ambrosio et al.   PLATELETS

Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation

(2015) B. Estevez et al.   BLOOD

First characterization of platelet secretion defect in patients with familial hemophagocytic lymphohistiocytosis type 3 (FHL-3)

(2015) L. Nakamura et al.   BLOOD

The Exocyst at a Glance

(2015) B. Wu et al.   JOURNAL OF CELL SCIENCE

Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice

(2015) C. M. Williams et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Lysine acetyltransfer supports platelet function

(2015) J. E. Aslan et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα

(2015) Naadiya Carrim et al.   Redox Biology

Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1

(2014) Toshiaki Tanaka et al.   CELLULAR SIGNALLING

Copy Number Analysis of the Murine Platelet Proteome Spanning the Complete Abundance Range

(2014) Marlis Zeiler et al.   MOLECULAR & CELLULAR PROTEOMICS

RhoG Protein Regulates Platelet Granule Secretion and Thrombus Formation in Mice

(2013) Robert Goggs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Live-cell imaging of exocyst links its spatiotemporal dynamics to various stages of vesicle fusion

(2013) Felix Rivera-Molina et al.   JOURNAL OF CELL BIOLOGY

Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy

(2013) B. S. Ferguson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways

(2012) J. M. Burkhart et al.   BLOOD

Munc18b/STXBP2 is required for platelet secretion

(2012) R. Al Hawas et al.   BLOOD

Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion

(2012) S. Ye et al.   BLOOD

ERK1/2 Regulate Exocytosis through Direct Phosphorylation of the Exocyst Component Exo70

(2012) Jinqi Ren et al.   DEVELOPMENTAL CELL

RalB and the Exocyst Mediate the Cellular Starvation Response by Direct Activation of Autophagosome Assembly

(2011) Brian O. Bodemann et al.   CELL

Genetic and antibody-induced glycoprotein VI deficiency equally protects mice from mechanically and FeCl3-induced thrombosis

(2011) M. BENDER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A central role of GPIb-IX in the procoagulant function of platelets that is independent of the 45-kDa GPIb  N-terminal extracellular domain

(2010) C. Ravanat et al.   BLOOD

Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis

(2010) Q. Ren et al.   BLOOD

Sec5 and Exo84 Foster Oncogenic Ras-Mediated Tumorigenesis

(2010) S. H. Issaq et al.   MOLECULAR CANCER RESEARCH

RGD-ligand mimetic antagonists of integrin αIIbβ3 paradoxically enhance GPVI-induced human platelet activation

(2009) M. L. JONES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The Role of the Exocyst in Matrix Metalloproteinase Secretion and Actin Dynamics during Tumor Cell Invadopodia Formation

(2009) Jianglan Liu et al.   MOLECULAR BIOLOGY OF THE CELL

The Exocyst Protein Sec10 Is Necessary for Primary Ciliogenesis and Cystogenesis In Vitro

(2009) Xiaofeng Zuo et al.   MOLECULAR BIOLOGY OF THE CELL

Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes

(2008) Patrick D. Lyons et al.   BIOSCIENCE REPORTS