Article
Multidisciplinary Sciences
Linxuan Li, Tingting Zhu, Yun Song, Li Feng, Philip James Kear, Rooallah Saberi Riseh, Mahmoud Sitohy, Raju Datla, Maozhi Ren
Summary: This study explored the potential mechanisms of salicylic acid (SA) as a biofungicide by using the highly pathogenic Fusarium oxysporum as a model system. The results showed that SA could inhibit key targets of the pathogen, modify the metabolic activity within pathogen cells, and induce pathogen cell death. This research provides insights into the application of SA in controlling various fungal diseases by targeting the SNF1-TORC1 pathway of pathogens.
JOURNAL OF ADVANCED RESEARCH
(2022)
Review
Plant Sciences
Erin A. Stroud, Jay Jayaraman, Matthew D. Templeton, Erik H. A. Rikkerink
Summary: Defence phytohormone pathways have evolved to recognize and respond to various stressors in the environment. Salicylic acid and jasmonic acid, two important plant hormones, regulate different defense responses through the shared defense networks. The structure and regulation of the networks are crucial for the rapid establishment and longevity of hormonal signaling pathways in response to hormone treatment and different biotic stressors.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Yusong Liu, Qianwei Liu, Xuewen Li, Zhijun Zhang, Shukang Ai, Cheng Liu, Fengwang Ma, Chao Li
Summary: The study found that MdERF114 is expressed during F. solani infection in apple roots and positively regulates the resistance of apple roots to F. solani by activating the expression of the MdPRX63 gene, leading to lignin deposition in apple roots and increased resistance. This mechanism involving MdWRKY75-MdERF114-MdMYB8-MdPRX63 provides a promising strategy for preventing apple replant disease.
Review
Energy & Fuels
Asep Bayu, Diah Radini Noerdjito, Siti Irma Rahmawati, Masteria Yunovilsa Putra, Surachai Karnjanakom
Summary: This review presents the potential applications of red microalgae genus Porphyridium as a natural source of high-value chemicals and discusses their biological nature, culture strategies, and the effects of environmental factors on cell growth and biochemical yield. It also evaluates recent technology developments in large-scale cultivation.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Biochemistry & Molecular Biology
Claudia Elizabeth Ruiz-Davila, Karla Ivon Solis-Andrade, Miguel Olvera-Sosa, Gabriela Palestino, Sergio Rosales-Mendoza
Summary: Advanced materials used in biomedicine field include a diverse group of organic molecules such as polymers, polysaccharides, and proteins. The design and synthesis of core-shell microgels based on chitosan and Porphyridium exopolysaccharides (EPS) crosslinked with sodium tripolyphosphate (TPP) is described in this study. The size and properties of the microgels were influenced by factors such as reaction temperature, sonication time, exopolysaccharide concentration, pH, and TPP concentration. The obtained microgels showed potential in biomedical applications based on their characteristics and performance.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Plant Sciences
Katarina Sunic, Lidija Brkljacic, Rosemary Vukovic, Zorana Katanic, Branka Salopek-Sondi, Valentina Spanic
Summary: This study investigates the physiological and biochemical responses of wheat to Fusarium head blight (FHB) stress and finds that the activity of AsA-GSH metabolism increases in resistant varieties, while carotenoid levels decrease. These findings contribute to the understanding of FHB resistance mechanisms and provide insights for breeding resistant varieties.
Article
Multidisciplinary Sciences
Martine Rigault, Sylvie Citerne, Celine Masclaux-Daubresse, Alia Dellagi
Summary: Autophagy plays important roles in plant immunity, affecting the susceptibility of plants to pathogens. Mutations in genes related to autophagy can lead to increased susceptibility, mainly due to disruptions in hormonal balance.
SCIENTIFIC REPORTS
(2021)
Article
Plant Sciences
Diego Alberto Mengarelli, Lara Roldan Tewes, Salma Balazadeh, Maria Ines Zanor
Summary: The study demonstrates that fitness mutants with moderate levels of salicylic acid accumulation and SA signaling activated show restricted pathogen infection and higher seed set. NPR1 is found to be essential in these mutants for SA storage and defense activation, while the FITNESS transcriptional network includes defense-related transcription factors and JA related genes, modulating JA-related responses during pathogen attack.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Davide Liberti, Paola Imbimbo, Enrica Giustino, Luigi D'Elia, Melanie Silva, Luisa Barreira, Daria Maria Monti
Summary: The antioxidant and anti-inflammatory activities of sulfated exopolysaccharides (s-EPSs) and phycoerythrin (PE) from the red marine microalga Porphyridium cruentum (CCALA415) were evaluated. s-EPSs showed biocompatibility and high antioxidant activity, while PE demonstrated powerful antioxidant activity. Both molecules exhibited anti-inflammatory activity and facilitated tissue regeneration. Therefore, microalgae-derived compounds are excellent sources of antioxidants for various applications.
Article
Plant Sciences
Feiying Zhu, Zhiwei Wang, Yong Fang, Jianhua Tong, Jing Xiang, Kankan Yang, Ruozhong Wang
Summary: This study investigates the molecular mechanism of salicylic acid (SA), jasmonic acid (JA), and abscisic acid (ABA) in watermelon resistance against Fusarium wilt. The up-regulated expression of certain genes is found to be critical in defense against the pathogen. Additionally, there may be crosstalk between SA, JA, and ABA in triggering the plant immune system.
Article
Multidisciplinary Sciences
Xin Zhou, Jinting Wang, Fang Liu, Junmin Liang, Peng Zhao, Clement K. M. Tsui, Lei Cai
Summary: This study found that the diversity of rhizosphere microbiota is negatively correlated with Fusarium wilt disease in tomato plants. Cross-kingdom SynComs showed the best suppression effect against the disease, providing a new effective strategy for controlling soil-borne diseases.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Davide Liberti, Paola Imbimbo, Enrica Giustino, Luigi D'Elia, Giarita Ferraro, Angela Casillo, Anna Illiano, Gabriella Pinto, Maria Chiara Di Meo, Gerardo Alvarez-Rivera, Maria Michela Corsaro, Angela Amoresano, Armando Zarrelli, Elena Ibanez, Antonello Merlino, Daria Maria Monti
Summary: A biorefinery approach was developed to extract high-value bioproducts, including exopolysaccharides, phycoerythrin, and β-carotene, from the culture of Porphyridium cruentum.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Xiaodong Yu, Yiren Xu, Shunping Yan
Summary: The study found that in Arabidopsis, the ethylene signaling transcription factors EIN3 and EIL1 are involved in SA-induced leaf senescence, and ET enhances the effect of SA in promoting senescence, NPR1 interacts with EIN3 to promote its transcriptional activity. This suggests that SA and ET work together in senescence, in contrast to their antagonistic crosstalk in other biological processes.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Weihao Miao, Lijiao Ge, Yuean Wang, Song Li, Daojin Sun, Ye Liu, Zhiyong Guan, Sumei Chen, Weimin Fang, Fadi Chen, Shuang Zhao
Summary: This study analyzed the resistance of chrysanthemums to fungal infection and found that the CmWRKY8-1 gene regulates the expression of genes related to the SA signaling pathway, thereby reducing resistance to F. oxysporum.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agricultural Engineering
Maria Stasinska-Jakubas, Barbara Hawrylak-Nowak, Slawomir Dresler, Magdalena Wojciak, Katarzyna Rubinowska
Summary: Plant elicitors, such as chitosan lactate and salicylic acid, have been extensively used to increase the production of secondary metabolites in vitro. In vivo studies are still needed to fully understand the biological basis of elicitation. Among the compounds studied, chitosan lactate and salicylic acid showed the strongest elicitation effects on phenolic metabolites in lemon balm, while a mixture of elicitors did not significantly change metabolite levels. Additionally, the highest concentrations of metabolites were observed on the 8th day of elicitation, and the elicitors also increased antioxidant activity in plant extracts.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Plant Sciences
Anil Kumar Patel, Akash Pralhad Vadrale, Reeta Rani Singhania, Philippe Michaud, Ashok Pandey, Shu-Jen Chen, Chiu-Wen Chen, Cheng-Di Dong
Summary: In recent years, algal polysaccharides have been extensively studied for pharmaceutical, nutraceutical, and biomedical applications due to their promising bioactive properties. They are also increasingly being used in industrial and dietary sectors. The marine algae contain a variety of polysaccharides that have a significant impact on the global economy. In the pharmaceutical and biomedicine industries, alginates, fucoidans, ulvans, carrageenans, and chitin are becoming increasingly important.
PHYTOCHEMISTRY REVIEWS
(2023)
Article
Environmental Sciences
Olfa Baccari, Mohamed Barkallah, Jihen Elleuch, Nourelhouda Ben Ayed, Amel Chtourou, Hela Karray-Hakim, Adenene Hammami, Philippe Michaud, Imen Fendri, Slim Abdelkafi
Summary: Parachlamydia acanthamoebae, a potential respiratory pathogen, was detected using a TaqMan-PCR assay that showed good accuracy and reproducibility. This diagnostic tool can be used for large-scale screening and during outbreaks.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemical Research Methods
Olfa Baccari, Mohamed Barkallah, Jihen Elleuch, Nourelhouda Ben Ayed, Amel Chtourou, Hela Karray-Hakim, Adenene Hammami, Philippe Michaud, Imen Fendri, Slim Abdelkafi
Summary: This study developed a new duplex probe-based q-PCR assay for simultaneous detection and quantification of Parachlamydia acanthamoebae and Simkania negevensis. The assay showed high accuracy and sensitivity in detecting these bacteria in water and clinical samples.
ANALYTICAL BIOCHEMISTRY
(2023)
Article
Chemistry, Medicinal
Meriem Aitouguinane, Zainab El Alaoui-Talibi, Halima Rchid, Imen Fendri, Slim Abdelkafi, Mohamed Didi Ould El-Hadj, Zakaria Boual, Didier Le Cerf, Christophe Rihouey, Christine Gardarin, Pascal Dubessay, Philippe Michaud, Guillaume Pierre, Cedric Delattre, Cherkaoui El Modafar
Summary: The study investigated the ability of alginates extracted from two Moroccan brown seaweeds and their derivatives to induce phenolic metabolism in tomato seedlings. Elicitation was done by foliar spraying the seaweed alginates on tomato seedlings and evaluating their effects on PAL activity, polyphenol, and lignin production. It was found that low-molecular-weight alginates were more effective in inducing natural defenses in tomato seedlings compared to the alginate polymers. These findings suggest that low-molecular-weight alginates may have potential as a stimulant for plant natural defenses.
Article
Chemistry, Physical
Jihane Zeghlouli, Nicola Schiavone, Haroutioun Askanian, Amine Guendouz, Cherkaoui El Modafar, Philippe Michaud, Cedric Delattre
Summary: Extrusion and hot compressing molding processes were used to fabricate BioPE composites reinforced with argan byproducts as bio-fillers. The mechanical properties of the composites were investigated by dynamical mechanical analysis and rheological testing. The results showed that the addition of argan byproducts improved the mechanical properties of the composites. Furthermore, the thermal analysis revealed that the bio-fillers reduced the decomposition temperatures of the polymer. This study offers an environmentally friendly alternative for utilizing underutilized biomass and has the potential to create new markets for argan byproducts.
Article
Polymer Science
Gwendoline Christophe, Xiaoyang Hou, Emmanuel Petit, Mounir Traikia, Didier Le Cerf, Christophe Rihouey, Christine Gardarin, Cedric Delattre, Philippe Michaud, Guillaume Pierre, Pascal Dubessay
Summary: This study identified Peteryoungia rosettifformans as a wild producer of an exopolysaccharide related to glucuronan. Structural and biochemical analyses revealed that the polysaccharide had a molecular mass of 1.85 x 10(5) Da and was partially O-acetylated at C-2 and/or C-3 positions. The concentration of Mg2+ ions in the cultivation medium was found to impact the structure of the polysaccharide.
Article
Chemistry, Multidisciplinary
Ali Forouhar, Nasser Hamdami, Gholamreza Djelveh, Christine Gardarin, Guillaume Pierre, Alina Violeta Ursu, Philippe Michaud
Summary: Ultrasound pretreatment and microwave-assisted extraction (MAE) techniques were used to extract pectin from watermelon rind. The study found that ultrasonic pretreatment changed the morphology and increased the porosity of the raw powder, facilitating the extraction process. The highest extraction yield of pectin was achieved with 5 minutes of extraction at 500 W ultrasonic pretreatment.
APPLIED SCIENCES-BASEL
(2023)
Article
Chemistry, Multidisciplinary
Hana Derbel, Jihen Elleuch, Wael Mahfoudh, Philippe Michaud, Imen Fendri, Slim Abdelkafi
Summary: Bioactive peptides extracted from microalgae have gained significant attention recently due to their promising properties. In this study, proteins from the marine microalga Rhodomonas sp. were hydrolyzed into peptides using alcalase and pepsin. The biological activities of the protein preparations were evaluated and it was found that the crude protein exhibited higher antioxidant and anti-inflammatory activities compared to the peptides obtained after hydrolysis.
APPLIED SCIENCES-BASEL
(2023)
Review
Chemistry, Medicinal
Latifa Tounsi, Hajer Ben Hlima, Faiez Hentati, Ons Hentati, Hana Derbel, Philippe Michaud, Slim Abdelkafi
Summary: This review provides a detailed overview of optimizing culture media elements and physical parameters to improve the large-scale production of phycobiliproteins. It also explores the main features of phycobiliproteins and examines their potential for biotechnological uses in various fields, with a focus on health and nutritional claims.
Article
Biotechnology & Applied Microbiology
Claire Toucheteau, Valentine Deffains, Clement Gaignard, Christophe Rihouey, Celine Laroche, Guillaume Pierre, Olivier Lepine, Ian Probert, Didier Le Cerf, Philippe Michaud, Ingrid Arnaudin-Fruitier, Nicolas Bridiau, Thierry Maugard
Summary: This study isolated and depolymerized exopolysaccharides (EPS) from different microalgae, characterized their structural features, and investigated their effects on collagen activity. The depolymerized EPS forms enhanced collagen production, and the inhibition of collagenase activity was strongly correlated to the sulfate group content of EPS. These findings provide new insights into the dermo-cosmetic potential of microalgae EPS.
Article
Environmental Sciences
Aziza Safaa Chenine, Zakaria Boual, Mohamed Didi Ould Elhadj, Noura Addoun, Reguia Mahfoudi, Aicha Khemili, Hakim Belkhalfa, Khaldoun Bachari, Imen Fendri, Cherkaoui El Modafar, Zainab Alaoui Talibi, Pascal Dubessay, Cedric Delattre, Guillaume Pierre, Philippe Michaud, Jihen Elleuch, Slim Abdelkafi
Summary: This study investigates the impact of partial acid hydrolysis on the antihyperglycemic activity of a polysaccharide derived from Plantago ciliata seeds. The results demonstrate that the resulting oligosaccharides exhibit significant inhibitory effects on alpha-amylase and alpha-D-glucosidase enzymes and act as non-competitive inhibitors. Additionally, these oligosaccharides show resistance to digestion, suggesting their potential as a natural and healthy drug for reducing blood sugar levels.
EURO-MEDITERRANEAN JOURNAL FOR ENVIRONMENTAL INTEGRATION
(2023)
Article
Biochemistry & Molecular Biology
Ines Schmidt-Morgenroth, Philippe Michaud, Fabrizio Gasparini, Alexandre Avrameas
Summary: Mild cognitive impairment (MCI) is characterized by a decline in cognitive function and is an underlying condition of Alzheimer's disease (AD). Neuroinflammation has been investigated as a mechanism contributing to the progression of MCI to AD. Understanding this mechanism could help in the diagnosis and treatment of patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Farah Hadjkacem, Jihen Elleuch, Meriem Aitouguinane, Fatma Zohra Chakou, Alina Violeta Ursu, Pascal Dubessay, Nathalie Bourgougnon, Mounir Traikia, Didier Le Cerf, Zainab El Alaoui-Talibi, Cherkaoui El Modafar, Zakaria Boual, Mohamed Didi Ould El Hadj, Cedric Delattre, Gwendoline Christophe, Philippe Michaud, Imen Fendri, Slim Abdelkafi, Guillaume Pierre
Summary: This study evaluates the biological and biotechnological potentials of two water soluble polysaccharides (alginate and fucoidan) extracted from a Tunisian brown macroalgae. The polysaccharides showed significant anti-inflammatory, anticoagulant, antihyperglycemic, and antiviral activities, as well as the ability to activate the natural defenses of tomato seedlings.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
