Nucleophosmin Protein Dephosphorylation by DUSP3 Is a Fine-Tuning Regulator of p53 Signaling to Maintain Genomic Stability

SIRT7-dependent deacetylation of NPM promotes p53 stabilization following UV-induced genotoxic stress

(2021) Alessandro Ianni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DUSP3 maintains genomic stability and cell proliferation through modulation of the NER pathway and cell cycle regulatory proteins

(2020) Lilian Cristina Russo et al.   CELL CYCLE

Nucleophosmin interaction with APE1: Insights into DNA repair regulation

(2020) David J. López et al.   DNA REPAIR

Nuclear actin dynamics in gene expression and genome organization

(2019) Salla Kyheröinen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Identification of a novel nucleophosmin-interaction motif in the tumor suppressor p14arf

(2018) Enrico Luchinat et al.   FEBS Journal

Monitoring of nucleophosmin oligomerization in live cells

(2018) Aleš Holoubek et al.   Methods and Applications in Fluorescence

Revisiting the roles of VHR/DUSP3 phosphatase in human diseases

(2018) LC Russo et al.   Clinics

Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration

(2017) Y-R Chen et al.   ONCOGENE

Census and evaluation of p53 target genes

(2017) M Fischer   ONCOGENE

Tetramer formation of tumor suppressor protein p53: Structure, function, and applications

(2016) Rui Kamada et al.   BIOPOLYMERS

Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2

(2016) Zhuo Ren et al.   Cell Death & Disease

GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF

(2016) Sun Lee et al.   Oncotarget

Combined experimental and bioinformatics analysis for the prediction and identification of VHR/DUSP3 nuclear targets related to DNA damage and repair

(2015) Fabio Luis Forti   Integrative Biology

GLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer

(2015) Jee-Youn Kim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of p14ARF-HDM2-p53 axis in SOX6-mediated tumor suppression

(2015) J Wang et al.   ONCOGENE

Cytoplasmic nucleophosmin has elevated T199 phosphorylation upon which G2/M phase progression is dependent

(2015) Narisa Chan et al.   Scientific Reports

AKT regulates NPM dependent ARF localization and p53mut stability in tumors

(2015) Garth Hamilton et al.   Oncotarget

Targeting Nucleophosmin 1 Represents a Rational Strategy for Radiation Sensitization

(2014) Konjeti R. Sekhar et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins

(2014) Mattia Poletto et al.   MOLECULAR BIOLOGY OF THE CELL

Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters

(2014) Jayne Loughery et al.   NUCLEIC ACIDS RESEARCH

Structural polymorphism in the N-terminal oligomerization domain of NPM1

(2014) D. M. Mitrea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic, Cellular, and Network Analyses Reveal New DUSP3 Interactions with Nucleolar Proteins in HeLa Cells

(2013) Karine Panico et al.   JOURNAL OF PROTEOME RESEARCH

Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology

(2013) C Vascotto et al.   ONCOGENE

Proteasome Activity Influences UV-Mediated Subnuclear Localization Changes of NPM

(2013) Henna M. Moore et al.   PLoS One

In silico studies of potential phosphoresidues in the human nucleophosmin/B23: Its kinases and related biological processes

(2012) Gioser Ramos-Echazábal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Multifunctional Protein Nucleophosmin (NPM1) Is a Human Linker Histone H1 Chaperone

(2011) Shrikanth S. Gadad et al.   BIOCHEMISTRY

Towards a mechanism for histone chaperones

(2011) Simon J. Elsässer et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Vaccinia H1-related Phosphatase Is a Phosphatase of ErbB Receptors and Is Down-regulated in Non-small Cell Lung Cancer

(2011) Jiz-Yuh Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recruitment of Phosphorylated NPM1 to Sites of DNA Damage through RNF8-Dependent Ubiquitin Conjugates

(2010) A. Koike et al.   CANCER RESEARCH

p53 post-translational modification: deregulated in tumorigenesis

(2010) Chao Dai et al.   TRENDS IN MOLECULAR MEDICINE

Sustained activation of p53 in confluent nucleotide excision repair-deficient cells resistant to ultraviolet-induced apoptosis

(2008) Helotonio Carvalho et al.   DNA REPAIR

Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia

(2008) Charles G. Grummitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY