Maternal UHRF1 Is Essential for Transcription Landscapes and Repression of Repetitive Elements During the Maternal-to-Zygotic Transition

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

(2020) Aditya Sankar et al.   NATURE CELL BIOLOGY

Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program

(2019) Mélanie Eckersley-Maslin et al.   GENES & DEVELOPMENT

DPPA2 and DPPA4 are necessary to establish a 2C‐like state in mouse embryonic stem cells

(2019) Alberto De Iaco et al.   EMBO REPORTS

Deletion of maternal UHRF1 severely reduces mouse oocyte quality and causes developmental defects in preimplantation embryos

(2019) Yumeng Cao et al.   FASEB JOURNAL

UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells

(2019) Juan Dong et al.   Nature Communications

MLL2 conveys transcription-independent H3K4 trimethylation in oocytes

(2018) Courtney W. Hanna et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

(2018) Kun-Yong Kim et al.   Nature Communications

MLL2 conveys transcription-independent H3K4 trimethylation in oocytes

(2018) Courtney W. Hanna et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1

(2018) Yingfeng Li et al.   NATURE

A molecular roadmap for the emergence of early-embryonic-like cells in culture

(2017) Diego Rodriguez-Terrones et al.   NATURE GENETICS

CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes

(2017) Chao Yu et al.   Cell Reports

Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos

(2017) Shoji Maenohara et al.   PLoS Genetics

Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration

(2016) Vidya Ramesh et al.   GENES & DEVELOPMENT

Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos

(2016) Xiaoyu Liu et al.   NATURE

Allelic reprogramming of the histone modification H3K4me3 in early mammalian development

(2016) Bingjie Zhang et al.   NATURE

Multiple LINEs of retrotransposon silencing mechanisms in the mammalian germline

(2016) Fang Yang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation

(2016) Katia Ancelin et al.   eLife

Paternal H3K4 methylation is required for minor zygotic gene activation and early mouse embryonic development

(2015) K. Aoshima et al.   EMBO REPORTS

Effects of ERα-specific antagonist on mouse preimplantation embryo development and zygotic genome activation

(2015) Yanqin Zhang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Zygotic Genome Activation During the Maternal-to-Zygotic Transition

(2014) Miler T. Lee et al.   Annual Review of Cell and Developmental Biology

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development

(2014) Gen-Bao Shao et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

The DNA methylation landscape of human early embryos

(2014) Hongshan Guo et al.   NATURE

5-Hydroxymethylcytosine is a predominantly stable DNA modification

(2014) Martin Bachman et al.   Nature Chemistry

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity

(2014) Xinyi Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis

(2013) S.-J. Park et al.   GENES & DEVELOPMENT

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing

(2013) Zhigang Xue et al.   NATURE

Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA

(2013) Anas Fadloun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9

(2013) Xiaoli Liu et al.   Nature Communications

Abnormality of maternal-to-embryonic transition contributes to MEHP-induced mouse 2-cell block

(2012) Da-Peng Chu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Embryonic stem cell potency fluctuates with endogenous retrovirus activity

(2012) Todd S. Macfarlan et al.   NATURE

Transcript clearance during the maternal-to-zygotic transition

(2011) Claudia B Walser et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A

(2011) Todd S. Macfarlan et al.   GENES & DEVELOPMENT

UHRF1 Double Tudor Domain and the Adjacent PHD Finger Act Together to Recognize K9me3-Containing Histone H3 Tail

(2011) Si Xie et al.   JOURNAL OF MOLECULAR BIOLOGY

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

(2011) Tian-Peng Gu et al.   NATURE

5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

(2011) Hume Stroud et al.   GENOME BIOLOGY

The maternal-to-zygotic transition: a play in two acts

(2009) W. Tadros et al.   DEVELOPMENT

L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism

(2009) H. Kano et al.   GENES & DEVELOPMENT

Retrotransposon expression as a defining event of genome reprograming in fertilized and cloned bovine embryos

(2009) L C Bui et al.   REPRODUCTION

Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos

(2008) Pengpeng Ma et al.   DEVELOPMENTAL BIOLOGY

Cell cycle regulation during early mouse embryogenesis

(2007) Jérôme Artus et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY