Contribution of neovascularization and intraplaque haemorrhage to atherosclerotic plaque progression and instability

IL-1 Blockade in Autoinflammatory Syndromes

(2014) Adriana A. Jesus et al.   Annual Review of Medicine

Relationship between cholesterol crystals and culprit lesion characteristics in patients with stable coronary artery disease: an optical coherence tomography study

(2014) Shunichi Nakamura et al.   Clinical Research in Cardiology

Assessment of Coronary Atherosclerosis using Optical Coherence Tomography

(2014) Takashi Kubo et al.   Journal of Atherosclerosis and Thrombosis

Relationship between Enhanced Intensity of Contrast Enhanced Ultrasound and Microvessel Density of Aortic Atherosclerostic Plaque in Rabbit Model

(2014) Xiangdong You et al.   PLoS One

Nonsteroidal anti-inflammatory drugs and antihypertensives: how do they relate?

(2014) Zovinar Der Khatchadourian et al.   Oral Surgery Oral Medicine Oral Pathology Oral Radiology

Effects of Interleukin-1 Blockade With Anakinra on Adverse Cardiac Remodeling and Heart Failure After Acute Myocardial Infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) Pilot Study]

(2013) Antonio Abbate et al.   AMERICAN JOURNAL OF CARDIOLOGY

Coronary stents: historical development, current status and future directions

(2013) J. Iqbal et al.   BRITISH MEDICAL BULLETIN

Vascular Extracellular Matrix in Atherosclerosis

(2013) Dimitry A. Chistiakov et al.   Cardiology in Review

Th17 cells and IL-17 are involved in the disruption of vulnerable plaques triggered by short-term combination stimulation in apolipoprotein E-knockout mice

(2013) Tian Ma et al.   Cellular & Molecular Immunology

Characterization of CD4+CD28null T cells in patients with coronary artery disease and individuals with risk factors for atherosclerosis

(2013) Fábio Haach Téo et al.   CELLULAR IMMUNOLOGY

Atherogenesis May Involve the Prooxidant and Proinflammatory Effects of Ferryl Hemoglobin

(2013) László Potor et al.   Oxidative Medicine and Cellular Longevity

Macrophages Transmit Potent Proangiogenic Effects of oxLDL In Vitro and In Vivo Involving HIF-1α Activation: a Novel Aspect of Angiogenesis in Atherosclerosis

(2013) Randolph Hutter et al.   Journal of Cardiovascular Translational Research

Platelets enter atherosclerotic plaque via intraplaque microvascular leakage and intraplaque hemorrhage: A histopathological study in carotid plaques

(2012) Guus W. van Lammeren et al.   ATHEROSCLEROSIS

High Levels of Costimulatory Receptors OX40 and 4-1BB Characterize CD4 + CD28 null T Cells in Patients With Acute Coronary Syndrome

(2012) Ingrid E. Dumitriu et al.   CIRCULATION RESEARCH

Heme and haemoglobin direct macrophage Mhem phenotype and counter foam cell formation in areas of intraplaque haemorrhage

(2012) Joseph J. Boyle   CURRENT OPINION IN LIPIDOLOGY

Anti-inflammatory Treatment of Acute Coronary Syndromes

(2012) R. Della Bona et al.   CURRENT PHARMACEUTICAL DESIGN

C-reactive protein induces expression of matrix metalloproteinase-9: A possible link between inflammation and plaque rupture

(2012) Giovanni Cimmino et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

From intraplaque haemorrhages to plaque vulnerability

(2012) Jean-Baptiste Michel et al.   Journal of Cardiovascular Medicine

Pathogenesis of Acute Coronary Syndromes

(2012) Filippo Crea et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of Statins on Cholesterol Crystallization and Atherosclerotic Plaque Stabilization

(2011) George S. Abela et al.   AMERICAN JOURNAL OF CARDIOLOGY

Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model

(2011) Jian-Xiong Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Plaque Rupture and Thrombosis Are Reduced by Lowering Cholesterol Levels and Crystallization With Ezetimibe and Are Correlated With Fluorodeoxyglucose Positron Emission Tomography

(2011) Roshan Patel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Phosphatidylcholine hydroperoxide promotes VEGF-induced angiogenesis in endothelial cells and rat aorta ring cultures

(2011) Kiyotaka Nakagawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

IL-17 induces apoptosis of vascular endothelial cells — A potential mechanism for human acute coronary syndrome

(2011) Faliang Zhu et al.   CLINICAL IMMUNOLOGY

The Role of Matrix Metalloproteinases in Atherothrombosis

(2011) Daniel F. J. Ketelhuth et al.   Current Atherosclerosis Reports

Intraplaque haemorrhages as the trigger of plaque vulnerability

(2011) J.-B. Michel et al.   EUROPEAN HEART JOURNAL

The Impact of Circulating Cholesterol Crystals on Vasomotor Function

(2011) Nitesh Gadeela et al.   JACC-Cardiovascular Interventions

Hemoglobin Directs Macrophage Differentiation and Prevents Foam Cell Formation in Human Atherosclerotic Plaques

(2011) Aloke V. Finn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Proteomic Focus on the Alterations Occurring at the Human Atherosclerotic Coronary Intima

(2011) Fernando de la Cuesta et al.   MOLECULAR & CELLULAR PROTEOMICS

Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot Study)

(2010) Antonio Abbate et al.   AMERICAN JOURNAL OF CARDIOLOGY

Red Cells, Hemoglobin, Heme, Iron, and Atherogenesis

(2010) Emőke Nagy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High Neutrophil Numbers in Human Carotid Atherosclerotic Plaques Are Associated With Characteristics of Rupture-Prone Lesions

(2010) Mihaela G. Ionita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Concept of Vulnerable/Unstable Plaque

(2010) Aloke V. Finn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Consistent differences in protein distribution along the longitudinal axis in symptomatic carotid atherosclerotic plaques

(2010) Fredrik J. Olson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Haemin-enhanced expression of haem oxygenase-1 stabilizes erythrocyte-induced vulnerable atherosclerotic plaques

(2010) Hui Li Lin et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Genetics of Vascular Complications in Diabetes Mellitus

(2010) Dan Farbstein et al.   CARDIOLOGY CLINICS

REVIEW: Stent Thrombosis-Risk Assessment and Prevention

(2010) Zuzana Motovska et al.   Cardiovascular Therapeutics

Composition of Carotid Atherosclerotic Plaque Is Associated With Cardiovascular Outcome

(2010) Willem E. Hellings et al.   CIRCULATION

Targeting IL-1β in disease; the expanding role of NLRP3 inflammasome

(2010) Ioannis Mitroulis et al.   European Journal of Internal Medicine

Molecular imaging of inflammation and intraplaque vasa vasorum: A step forward to identification of vulnerable plaques?

(2010) Gerrit L. ten Kate et al.   JOURNAL OF NUCLEAR CARDIOLOGY

Atheroembolic renal disease

(2010) Francesco Scolari et al.   LANCET

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Anti-Vascular Endothelial Growth Factor Therapies and Cardiovascular Toxicity: What Are the Important Clinical Markers to Target?

(2010) C. Vaklavas et al.   ONCOLOGIST

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Effect of Cholesterol Crystals on Plaques and Intima in Arteries of Patients With Acute Coronary and Cerebrovascular Syndromes

(2009) George S. Abela et al.   AMERICAN JOURNAL OF CARDIOLOGY

Coronary Intraplaque Hemorrhage Evokes a Novel Atheroprotective Macrophage Phenotype

(2009) Joseph J. Boyle et al.   AMERICAN JOURNAL OF PATHOLOGY

The vasa vasorum in diseased and nondiseased arteries

(2009) Mary Jo Mulligan-Kehoe   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Haptoglobin: Basic and Clinical Aspects

(2009) Andrew P. Levy et al.   ANTIOXIDANTS & REDOX SIGNALING

Adenosine Modulates HIF-1α, VEGF, IL-8, and Foam Cell Formation in a Human Model of Hypoxic Foam Cells

(2009) Stefania Gessi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Low vasa vasorum densities correlate with inflammation and subintimal thickening: Potential role in location—Determination of atherogenesis

(2009) M. Gössl et al.   ATHEROSCLEROSIS

Prevention of vasa vasorum neovascularization attenuates early neointima formation in experimental hypercholesterolemia

(2009) Mario Gössl et al.   BASIC RESEARCH IN CARDIOLOGY

Statin Use is Associated with a Significant Reduction in Cholesterol Content of Erythrocyte Membranes. A Novel Pleiotropic Effect?

(2009) Dimitrios N. Tziakas et al.   CARDIOVASCULAR DRUGS AND THERAPY

Immaturity of microvessels in haemorrhagic plaques is associated with proteolytic degradation of angiogenic factors

(2009) J. Le Dall et al.   CARDIOVASCULAR RESEARCH

Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability

(2009) Marika Massaro et al.   CARDIOVASCULAR RESEARCH

Angiogenesis as Risk Factor for Plaque Vulnerability

(2009) Rossella Di Stefano et al.   CURRENT PHARMACEUTICAL DESIGN

Enhanced expression of haemoglobin scavenger receptor in accumulated macrophages of culprit lesions in acute coronary syndromes

(2009) K. Yunoki et al.   EUROPEAN HEART JOURNAL

Thin-Walled Microvessels in Human Coronary Atherosclerotic Plaques Show Incomplete Endothelial Junctions

(2009) Judith C. Sluimer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Adverse effects of anticancer agents that target the VEGF pathway

(2009) Helen X. Chen et al.   Nature Reviews Clinical Oncology

Expansion of T-Cell Receptor ζ dim Effector T Cells in Acute Coronary Syndromes

(2008) Enrico Ammirati et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Disruption of Ang-1/Tie-2 Signaling Contributes to the Impaired Myocardial Vascular Maturation and Angiogenesis in Type II Diabetic Mice

(2008) Jian-Xiong Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thioredoxin in coronary culprit lesions: Possible relationship to oxidative stress and intraplaque hemorrhage

(2008) Kensaku Nishihira et al.   ATHEROSCLEROSIS

The phagocytes: neutrophils and monocytes

(2008) D. C. Dale et al.   BLOOD

CD4+CD28null T cells in coronary artery disease: when helpers become killers

(2008) I. E. Dumitriu et al.   CARDIOVASCULAR RESEARCH

The Th17/Treg imbalance in patients with acute coronary syndrome

(2008) Xiang Cheng et al.   CLINICAL IMMUNOLOGY

Statins alter neutrophil migration by modulating cellular Rho activity--a potential mechanism for statins-mediated pleotropic effects?

(2008) B. M. Maher et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Paradox of Hypoxic and Oxidative Stress in Atherosclerosis⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.

(2008) Manuel Mayr et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis

(2008) Judith C. Sluimer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Balance between Angiopoietin-1 and Angiopoietin-2 Is in Favor of Angiopoietin-2 in Atherosclerotic Plaques with High Microvessel Density

(2008) Simone Post et al.   JOURNAL OF VASCULAR RESEARCH

Effects of cyclic strain on endothelial cell apoptosis and tubulogenesis are dependent on ROS production via NAD(P)H subunit p22phox

(2008) Baijun Kou et al.   MICROVASCULAR RESEARCH

Pathological mechanisms of erythrocyte-induced vulnerability of atherosclerotic plaques

(2007) Hui-li Lin et al.   MEDICAL HYPOTHESES