Plaque Rupture and Thrombosis Are Reduced by Lowering Cholesterol Levels and Crystallization With Ezetimibe and Are Correlated With Fluorodeoxyglucose Positron Emission Tomography

Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation

(2010) George S. Abela   Journal of Clinical Lipidology

Imaging Atherosclerotic Plaque Inflammation by Fluorodeoxyglucose With Positron Emission Tomography

(2010) James H.F. Rudd et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Effect of Cholesterol Crystals on Plaques and Intima in Arteries of Patients With Acute Coronary and Cerebrovascular Syndromes

(2009) George S. Abela et al.   AMERICAN JOURNAL OF CARDIOLOGY

Ezetimibe reduces plaque inflammation in a rabbit model of atherosclerosis and inhibits monocyte migration in addition to its lipid-lowering effect

(2009) D Gómez-Garre et al.   BRITISH JOURNAL OF PHARMACOLOGY

A robust rabbit model of human atherosclerosis and atherothrombosis

(2009) Alkystis Phinikaridou et al.   JOURNAL OF LIPID RESEARCH

Quantification of Inflammation Within Rabbit Atherosclerotic Plaques Using the Macrophage-Specific CT Contrast Agent N1177: A Comparison with 18F-FDG PET/CT and Histology

(2009) F. Hyafil et al.   JOURNAL OF NUCLEAR MEDICINE

FDG-Accumulating Atherosclerotic Plaques Identified with 18F-FDG-PET/CT in 141 Patients

(2009) Johan A. Wassélius et al.   MOLECULAR IMAGING AND BIOLOGY

Detection of Neovessels in Atherosclerotic Plaques of Rabbits Using Dynamic Contrast Enhanced MRI and 18F-FDG PET

(2008) Claudia Calcagno et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Physical factors that trigger cholesterol crystallization leading to plaque rupture

(2008) Ameeth Vedre et al.   ATHEROSCLEROSIS

Noninvasive Detection and Localization of Vulnerable Plaque and Arterial Thrombosis With Computed Tomography Angiography/Positron Emission Tomography

(2008) Kusai Aziz et al.   CIRCULATION