Towards a Framework for Better Understanding of Quiescent Cancer Cells

MYC Oncogene Contributions to Release of Cell Cycle Brakes

(2019) Lucía García-Gutiérrez et al.   Genes

A Niche-Dependent Myeloid Transcriptome Signature Defines Dormant Myeloma Cells

(2019) Weng Hua Khoo et al.   BLOOD

Validation of Molecular Typing for Endometrial Screening Test That Predicts Benign and Malignant Lesions

(2019) Xiaoqian Tuo et al.   Frontiers in Oncology

Acridine Orange: A Review of Novel Applications for Surgical Cancer Imaging and Therapy

(2019) Vadim A. Byvaltsev et al.   Frontiers in Oncology

Putting the brakes on the cell cycle: mechanisms of cellular growth arrest

(2019) Lindsey R Pack et al.   CURRENT OPINION IN CELL BIOLOGY

Aspartate is an endogenous metabolic limitation for tumour growth

(2018) Lucas B. Sullivan et al.   NATURE CELL BIOLOGY

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence

(2018) Laura Vera-Ramirez et al.   Nature Communications

Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy

(2018) Hussein F. Aqbi et al.   Oncotarget

A facile in vitro platform to study cancer cell dormancy under hypoxic microenvironments using CoCl2

(2018) Hak Rae Lee et al.   Journal of Biological Engineering

Single-cell RNA-Seq of lymphoma cancers reveals malignant B cell types and co-expression of T cell immune checkpoints

(2018) Noemi Andor et al.   BLOOD

Dormancy in cancer

(2018) Hiroko Endo et al.   CANCER SCIENCE

Chemotherapy resistance and stemness in mitotically quiescent human breast cancer cells identified by fluorescent dye retention

(2018) Lewis A. Quayle et al.   CLINICAL & EXPERIMENTAL METASTASIS

The histone chaperone complex FACT promotes proliferative switch of G 0 cancer cells

(2018) Ling Bi et al.   INTERNATIONAL JOURNAL OF CANCER

AKT1 low Quiescent Cancer Cells Promote Solid Tumor Growth

(2017) Cleidson P. Alves et al.   MOLECULAR CANCER THERAPEUTICS

Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma

(2017) Terence P. F. Gade et al.   RADIOLOGY

Characterization and functional analysis of a slow-cycling subpopulation in colorectal cancer enriched by cell cycle inducer combined chemotherapy

(2017) Feng-Hua Wu et al.   Oncotarget

Cell-cycle-dependent drug-resistant quiescent cancer cells induce tumor angiogenesis after chemotherapy as visualized by real-time FUCCI imaging

(2016) Shuya Yano et al.   CELL CYCLE

Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells

(2016) Kyle K. Payne et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The cell fate: senescence or quiescence

(2016) Menderes Yusuf Terzi et al.   MOLECULAR BIOLOGY REPORTS

Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells

(2016) Pierre Avril et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

The Role of Regulatory B Cell-Like Malignant Cells and Treg Cells in the Mouse Model of BCL1 Tumor Dormancy

(2016) Andrew BitMansour et al.   PLoS One

Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation

(2016) Z Xi et al.   Cell Death & Disease

Dormant tumor cells expressing LOXL2 acquire a stem-like phenotype mediating their transition to proliferative growth

(2016) Keren Weidenfeld et al.   Oncotarget

Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow

(2016) Kenji Yumoto et al.   Scientific Reports

Mechanisms of Cancer Cell Dormancy--Another Hallmark of Cancer?

(2015) A. C. Yeh et al.   CANCER RESEARCH

Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors

(2015) Xiaonan Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4

(2015) Sara R. Martins-Neves et al.   JOURNAL OF CELLULAR PHYSIOLOGY

NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes

(2015) Maria Soledad Sosa et al.   Nature Communications

Targeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells

(2015) Mu Yao et al.   Oncotarget

TBK1 Regulates Prostate Cancer Dormancy through mTOR Inhibition

(2015) Jin Koo Kim et al.   NEOPLASIA

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

A novel method for monitoring tumor proliferation in vivo using fluorescent dye DiD

(2014) Kenji Yumoto et al.   CYTOMETRY PART A

Dormancy of Cancer Cells with Suppression of AKT Activity Contributes to Survival in Chronic Hypoxia

(2014) Hiroko Endo et al.   PLoS One

Forkhead Box M1 Regulates Quiescence-Associated Radioresistance of Human Head and Neck Squamous Carcinoma Cells

(2014) Jaimee C. Eckers et al.   RADIATION RESEARCH

Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells

(2014) M. Ono et al.   Science Signaling

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

(2014) Xiaonan Zhang et al.   Nature Communications

Modelling mammalian cellular quiescence

(2014) G. Yao   Interface Focus

A novel cell-cycle-indicator, mVenus-p27K−, identifies quiescent cells and visualizes G0–G1 transition

(2014) Toshihiko Oki et al.   Scientific Reports

Hypoxia Selects for a Quiescent, CML Stem/Leukemia Initiating- Like Population Dependent on CBP/Catenin Transcription

(2014) Aiko Kida et al.   Current Molecular Pharmacology

A Novel Model of Dormancy for Bone Metastatic Breast Cancer Cells

(2013) R. Marlow et al.   CANCER RESEARCH

Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis

(2013) Y. Touil et al.   CLINICAL CANCER RESEARCH

G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol

(2013) Takeshi Yamada et al.   LEUKEMIA RESEARCH

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Contrasting Quiescent G0 Phase with Mitotic Cell Cycling in the Mouse Immune System

(2013) Michio Tomura et al.   PLoS One

The G0/G1 switch gene 2 (G0S2): Regulating metabolism and beyond

(2012) Bradlee L. Heckmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2

(2011) X.-Y. Pei et al.   BLOOD

Gap Junction-Mediated Import of MicroRNA from Bone Marrow Stromal Cells Can Elicit Cell Cycle Quiescence in Breast Cancer Cells

(2011) P. K. Lim et al.   CANCER RESEARCH

ERK1/2 and p38α/β Signaling in Tumor Cell Quiescence: Opportunities to Control Dormant Residual Disease

(2011) Maria Soledad Sosa et al.   CLINICAL CANCER RESEARCH

Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells

(2011) D. Z. Ewton et al.   MOLECULAR CANCER THERAPEUTICS

Asymmetric cancer cell division regulated by AKT

(2011) I. Dey-Guha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Slow-Cycling Therapy-Resistant Cancer Cells

(2011) Nathan Moore et al.   STEM CELLS AND DEVELOPMENT

Metastatic Growth from Dormant Cells Induced by a Col-I-Enriched Fibrotic Environment

(2010) D. Barkan et al.   CANCER RESEARCH

Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/Rb2

(2010) Jing Hu et al.   INTERNATIONAL JOURNAL OF CANCER

Human cancer cell lines: Experimental models for cancer cells in situ? For cancer stem cells?

(2009) W.C.G. van Staveren et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Cancer Stem Cells and Aneuploid Populations within Developing Tumors Are the Major Determinants of Tumor Dormancy

(2009) A. P. Kusumbe et al.   CANCER RESEARCH

Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma

(2009) Jennifer L. Dembinski et al.   CLINICAL & EXPERIMENTAL METASTASIS

Mirk Regulates the Exit of Colon Cancer Cells from Quiescence

(2009) Kideok Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Radio-copper-labeled Cu-ATSM: an indicator of quiescent but clonogenic cells under mild hypoxia in a Lewis lung carcinoma model

(2009) Myungmi Oh et al.   NUCLEAR MEDICINE AND BIOLOGY

Single-cell analysis demonstrates how nutrient deprivation creates apoptotic and quiescent cell populations in tumor cylindroids

(2008) Byoung-jin Kim et al.   BIOTECHNOLOGY AND BIOENGINEERING

Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton

(2008) D. Barkan et al.   CANCER RESEARCH