M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair macrophage for traumatic brain injury recovery

Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner

(2020) Emily F. Willis et al.   CELL

p38MAPK/SGK1 signaling regulates macrophage polarization in experimental autoimmune encephalomyelitis

(2019) Bo Li et al.   Aging-US

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

FACS isolation of endothelial cells and pericytes from mouse brain microregions

(2018) Elizabeth E Crouch et al.   Nature Protocols

PPARγ induces the gene expression of integrin ανβ5 to promote macrophage M2 polarization

(2018) Qinyu Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

(2017) Andrew I R Maas et al.   LANCET NEUROLOGY

High-dimensional, single-cell characterization of the brain's immune compartment

(2017) Ben Korin et al.   NATURE NEUROSCIENCE

Spatial transcriptomic analysis of cryosectioned tissue samples with Geo-seq

(2017) Jun Chen et al.   Nature Protocols

Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift

(2017) Yasir N. Jassam et al.   NEURON

Suppressor of Cytokine Signaling (SOCS)1 Regulates Interleukin-4 (IL-4)-activated Insulin Receptor Substrate (IRS)-2 Tyrosine Phosphorylation in Monocytes and Macrophages via the Proteasome

(2016) Sarah M. McCormick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury

(2016) Alok Kumar et al.   JOURNAL OF NEUROTRAUMA

Manganese-Enhanced Magnetic Resonance Imaging as a Diagnostic and Dispositional Tool after Mild-Moderate Blast Traumatic Brain Injury

(2016) Olga Rodriguez et al.   JOURNAL OF NEUROTRAUMA

Arginase inhibition attenuates arteriogenesis and interferes with M2 macrophage accumulation

(2016) Manuel Lasch et al.   LABORATORY INVESTIGATION

STAT4 knockout protects LPS-induced lung injury by increasing of MDSC and promoting of macrophage differentiation

(2016) Cuiping Fu et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Tim-3 promotes tumor-promoting M2 macrophage polarization by binding to STAT1 and suppressing the STAT1-miR-155 signaling axis

(2016) Xingwei Jiang et al.   OncoImmunology

Atorvastatin promotes human monocyte differentiation toward alternative M2 macrophages through p38 mitogen-activated protein kinase-dependent peroxisome proliferator-activated receptor γ activation

(2015) Ou Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CD68 acts as a major gateway for malaria sporozoite liver infection

(2015) Sung-Jae Cha et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Critical role of p38 MAPK in IL-4-induced alternative activation of peritoneal macrophages

(2014) Lidia Jiménez-Garcia et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Integration of Network Biology and Imaging to Study Cancer Phenotypes and Responses

(2014) Ye Tian et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Traumatic brain injury induces macrophage subsets in the brain

(2013) Christine L. Hsieh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

(2012) Yaming Wang et al.   NATURE IMMUNOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Characterization of the Effects of Cross-Linking of Macrophage CD44 Associated with Increased Phagocytosis of Apoptotic PMN

(2012) Simon P. Hart et al.   PLoS One

Temporal Changes in Cell Marker Expression and Cellular Infiltration in a Controlled Cortical Impact Model in Adult Male C57BL/6 Mice

(2012) Xuemei Jin et al.   PLoS One

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

A Method for Reducing Misclassification in the Extended Glasgow Outcome Score

(2010) Juan Lu et al.   JOURNAL OF NEUROTRAUMA

Impaired Expression of Neuroprotective Molecules in the HIF-1α Pathway following Traumatic Brain Injury in Aged Mice

(2009) Joshua Anderson et al.   JOURNAL OF NEUROTRAUMA

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Mouse closed head injury model induced by a weight-drop device

(2009) Michael A Flierl et al.   Nature Protocols

A CREB-C/EBP  cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

(2009) D. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

(2009) Ravid Shechter et al.   PLOS MEDICINE

Intranasal delivery of transforming growth factor-beta1 in mice after stroke reduces infarct volume and increases neurogenesis in the subventricular zone

(2008) Minmin Ma et al.   BMC NEUROSCIENCE

CD3-specific antibody–induced immune tolerance involves transforming growth factor-β from phagocytes digesting apoptotic T cells

(2008) Sylvain Perruche et al.   NATURE MEDICINE