QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions

Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis

(2020) Marcus Sucksdorff et al.   BRAIN

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

(2020) Marta Olah et al.   Nature Communications

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

(2019) Takahiro Masuda et al.   NATURE

Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis

(2019) Colm Elliott et al.   BRAIN

Association of Chronic Active Multiple Sclerosis Lesions With Disability In Vivo

(2019) Martina Absinta et al.   JAMA Neurology

Myeloid cell plasticity in the evolution of central nervous system autoimmunity

(2018) David A. Giles et al.   ANNALS OF NEUROLOGY

Magnetic susceptibility increases as diamagnetic molecules breakdown: Myelin digestion during multiple sclerosis lesion formation contributes to increase on QSM

(2018) Kofi Deh et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

High-resolution QSM for functional and structural depiction of subthalamic nuclei in DBS presurgical mapping

(2018) Alexey V. Dimov et al.   JOURNAL OF NEUROSURGERY

Longitudinal study of multiple sclerosis lesions using ultra-high field (7T) multiparametric MR imaging

(2018) Sanjeev Chawla et al.   PLoS One

MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity

(2018) Bishuang Cai et al.   Science Signaling

Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions

(2018) Ulrike W Kaunzner et al.   BRAIN

Directed Differentiation of Human Pluripotent Stem Cells to Microglia

(2017) Panagiotis Douvaras et al.   Stem Cell Reports

Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging

(2016) Assunta Dal-Bianco et al.   ACTA NEUROPATHOLOGICA

Quantitative Susceptibility Mapping and R2* Measured Changes during White Matter Lesion Development in Multiple Sclerosis: Myelin Breakdown, Myelin Debris Degradation and Removal, and Iron Accumulation

(2016) Y. Zhang et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Persistent 7-tesla phase rim predicts poor outcome in new multiple sclerosis patient lesions

(2016) Martina Absinta et al.   JOURNAL OF CLINICAL INVESTIGATION

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Quantitative Susceptibility Mapping in Parkinson's Disease

(2016) Christian Langkammer et al.   PLoS One

Quantitative Susceptibility Mapping of the Motor Cortex in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis

(2015) Andrew D. Schweitzer et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Reproducibility of quantitative susceptibility mapping in the brain at two field strengths from two vendors

(2015) Kofi Deh et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

(2014) Oleg Butovsky et al.   ANNALS OF NEUROLOGY

Multiple sclerosis lesion geometry in quantitative susceptibility mapping (QSM) and phase imaging

(2014) Sarah Eskreis-Winkler et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: Interpreting positive susceptibility and the presence of iron

(2014) Cynthia Wisnieff et al.   MAGNETIC RESONANCE IN MEDICINE

Iron Is a Sensitive Biomarker for Inflammation in Multiple Sclerosis Lesions

(2013) Veela Mehta et al.   PLoS One

Quantitative Susceptibility Mapping of Multiple Sclerosis Lesions at Various Ages

(2013) Weiwei Chen et al.   RADIOLOGY

An Automated Method to Quantify Microglia Morphology and Application to Monitor Activation State Longitudinally In Vivo

(2012) Cleopatra Kozlowski et al.   PLoS One

Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla

(2011) F. Bagnato et al.   BRAIN

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Morphology enabled dipole inversion for quantitative susceptibility mapping using structural consistency between the magnitude image and the susceptibility map

(2011) Jing Liu et al.   NEUROIMAGE

Imaging Cortical Lesions in Multiple Sclerosis With Ultra–High-Field Magnetic Resonance Imaging

(2010) David Pitt et al.   ARCHIVES OF NEUROLOGY

Quantitative susceptibility map reconstruction from MR phase data using bayesian regularization: Validation and application to brain imaging

(2009) Ludovic de Rochefort et al.   MAGNETIC RESONANCE IN MEDICINE

Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells

(2008) Richard G. Ruddell et al.   HEPATOLOGY