Machine Learning Identifies Complicated Sepsis Course and Subsequent Mortality Based on 20 Genes in Peripheral Blood Immune Cells at 24 H Post-ICU Admission

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

(2020) Kristina E Rudd et al.   LANCET

Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

(2019) Christopher W. Seymour et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The usefulness of C-reactive protein and procalcitonin to predict prognosis in septic shock patients: A multicenter prospective registry-based observational study

(2019) Seung Mok Ryoo et al.   Scientific Reports

Extracellular Chromatin Triggers Release of Soluble CEACAM8 Upon Activation of Neutrophils

(2019) Matthieu Ribon et al.   Frontiers in Immunology

Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patients

(2019) Akram Mohammed et al.   Scientific Reports

Biomarkers in Sepsis

(2018) Tjitske S.R. van Engelen et al.   CRITICAL CARE CLINICS

Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock*

(2018) Erin K. Stenson et al.   Pediatric Critical Care Medicine

A community approach to mortality prediction in sepsis via gene expression analysis

(2018) Timothy E. Sweeney et al.   Nature Communications

The Role of Phospholipase C Signaling in Macrophage-Mediated Inflammatory Response

(2018) Liqian Zhu et al.   Journal of Immunology Research

The 2018 Surviving Sepsis Campaign’s Treatment Bundle: When Guidelines Outpace the Evidence Supporting Their Use

(2018) Rory Spiegel et al.   ANNALS OF EMERGENCY MEDICINE

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer

(2018) Murugan Kalimutho et al.   EMBO Molecular Medicine

Applying Artificial Intelligence to Identify Physiomarkers Predicting Severe Sepsis in the PICU

(2018) Rishikesan Kamaleswaran et al.   Pediatric Critical Care Medicine

Olfactomedin 4 marks a subset of neutrophils in mice

(2018) Matthew N Alder et al.   Innate Immunity

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

A minimal set of physiomarkers in continuous high frequency data streams predict adult sepsis onset earlier

(2018) Franco van Wyk et al.   INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS

Prediction of sepsis patients using machine learning approach: A meta-analysis

(2018) Md. Mohaimenul Islam et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Interleukin-1 Receptor 2

(2017) Yuejiao Lang et al.   SHOCK

Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation

(2017) Alexander R. Moschen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

CLEC5A is a critical receptor in innate immunity against Listeria infection

(2017) Szu-Ting Chen et al.   Nature Communications

Brief Report: A Novel ELANE Mutation Associated With Inflammatory Arthritis, Defective NETosis, and Recurrent Parvovirus Infection

(2017) Uma Thanarajasingam et al.   Arthritis & Rheumatology

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations

(2016) Alexander R. Moschen et al.   Cell Host & Microbe

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model

(2016) Sarah J Atkinson et al.   MOLECULAR MEDICINE

Correlation and variable importance in random forests

(2016) Baptiste Gregorutti et al.   STATISTICS AND COMPUTING

Lactoferrin Suppresses Neutrophil Extracellular Traps Release in Inflammation

(2016) Koshu Okubo et al.   EBioMedicine

Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS

(2015) Kirsten Neudoerffer Kangelaris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Expression and clinical significance of Centrosomal protein 55 (CEP55) in human urinary bladder transitional cell carcinoma

(2015) P.K. Singh et al.   IMMUNOBIOLOGY

Serum Syndecan-4 as a Possible Biomarker in Patients With Acute Pneumonia

(2015) Takefumi Nikaido et al.   JOURNAL OF INFECTIOUS DISEASES

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set

(2015) Timothy E. Sweeney et al.   Science Translational Medicine

Matrix Metalloproteinase-8 Plays a Pivotal Role in Neuroinflammation by Modulating TNF-α Activation

(2014) Eun-Jung Lee et al.   JOURNAL OF IMMUNOLOGY

Update on Procalcitonin Measurements

(2014) Michael Meisner   Annals of Laboratory Medicine

Metabolomics as a Novel Approach for Early Diagnosis of Pediatric Septic Shock and Its Mortality

(2013) Beata Mickiewicz et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Post-ICU Admission Fluid Balance and Pediatric Septic Shock Outcomes

(2013) Kamal Abulebda et al.   CRITICAL CARE MEDICINE

An instance level analysis of data complexity

(2013) Michael R. Smith et al.   MACHINE LEARNING

Transcriptional Instability during Evolving Sepsis May Limit Biomarker Based Risk Stratification

(2013) Antonia Kwan et al.   PLoS One

Identifying Key Regulatory Genes in the Whole Blood of Septic Patients to Monitor Underlying Immune Dysfunctions

(2013) Grant P. Parnell et al.   SHOCK

Gram-positive and gram-negative bacterial toxins in sepsis

(2013) Girish Ramachandran   Virulence

Peripheral blood RNA gene expression profiling in patients with bacterial meningitis

(2013) Margit Lill et al.   Frontiers in Neuroscience

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children

(2012) Adam D Irwin et al.   BMC Medical Genomics

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Procalcitonin assay in systemic inflammation, infection, and sepsis: Clinical utility and limitations

(2009) Kenneth L. Becker et al.   CRITICAL CARE MEDICINE

Matrix Metalloproteinase-8 Inactivates Macrophage Inflammatory Protein-1  To Reduce Acute Lung Inflammation and Injury in Mice

(2009) P. A. Quintero et al.   JOURNAL OF IMMUNOLOGY

Discovery of the gene signature for acute lung injury in patients with sepsis

(2009) Judie A. Howrylak et al.   PHYSIOLOGICAL GENOMICS

Cluster-based under-sampling approaches for imbalanced data distributions

(2008) Show-Jane Yen et al.   EXPERT SYSTEMS WITH APPLICATIONS

CLEC5A is critical for dengue-virus-induced lethal disease

(2008) Szu-Ting Chen et al.   NATURE