Systems Biology Analysis of the Radiation-Attenuated Schistosome Vaccine Reveals a Role for Growth Factors in Protection and Hemostasis Inhibition in Parasite Survival

Epitope Mapping of Exposed Tegument and Alimentary Tract Proteins Identifies Putative Antigenic Targets of the Attenuated Schistosome Vaccine

(2021) Leonardo P. Farias et al.   Frontiers in Immunology

Transcriptome of the parasitic flatworm Schistosoma mansoni during intra-mammalian development

(2020) Arporn Wangwiwatsin et al.   PLoS Neglected Tropical Diseases

Fifteen Years of Sm-p80-Based Vaccine Trials in Nonhuman Primates: Antibodies From Vaccinated Baboons Confer Protection in vivo and in vitro From Schistosoma mansoni and Identification of Putative Correlative Markers of Protection

(2020) Weidong Zhang et al.   Frontiers in Immunology

Endocan regulates acute lung inflammation through control of leukocyte diapedesis

(2019) Alexandre Gaudet et al.   JOURNAL OF APPLIED PHYSIOLOGY

In vitro Evidence of Human Immune Responsiveness Shows the Improved Potential of a Recombinant BCG Strain for Bladder Cancer Treatment

(2019) Dunia Rodriguez et al.   Frontiers in Immunology

A Praziquantel Treatment Study of Immune and Transcriptome Profiles in Schistosoma haematobium-Infected Gabonese Schoolchildren

(2019) Lucja A Labuda et al.   JOURNAL OF INFECTIOUS DISEASES

Here, there and everywhere: Resistin-like molecules in infection, inflammation, and metabolic disorders

(2018) Gabrielle M. Pine et al.   CYTOKINE

Advancing the Development of a Human Schistosomiasis Vaccine

(2018) Peter J. Hotez et al.   TRENDS IN PARASITOLOGY

Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

(2017) Dmitri Kazmin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant BCG expressing a PspA-PdT fusion protein protects mice against pneumococcal lethal challenge in a prime-boost strategy

(2017) Cibelly Goulart et al.   VACCINE

Schistosomiasis is more prevalent than previously thought: what does it mean for public health goals, policies, strategies, guidelines and intervention programs?

(2017) Daniel G. Colley et al.   Infectious Diseases of Poverty

Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons

(2017) Juan U. Rojo et al.   PLoS One

Do schistosome vaccine trials in mice have an intrinsic flaw that generates spurious protection data?

(2016) R. Alan Wilson et al.   Parasites & Vectors

CD4+T Cell Hyporesponsiveness after Repeated Exposure to Schistosoma mansoni Larvae Is Dependent upon Interleukin-10

(2015) Catriona T. Prendergast et al.   INFECTION AND IMMUNITY

Lessons learned in the analysis of high-dimensional data in vaccinomics

(2015) Ann L. Oberg et al.   VACCINE

Systems vaccinology: Enabling rational vaccine design with systems biological approaches

(2015) Thomas Hagan et al.   VACCINE

Modulation of influenza vaccine immune responses using an epidermal growth factor receptor kinase inhibitor

(2015) Joanna A. Pulit-Penaloza et al.   Scientific Reports

Vaccination against helminth parasite infections

(2014) James P Hewitson et al.   Expert Review of Vaccines

Schistosomes versus platelets

(2014) Akram A. Da’dara et al.   THROMBOSIS RESEARCH

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

(2013) Shuzhao Li et al.   NATURE IMMUNOLOGY

Immunization with tegument nucleotidases associated with a subcurative praziquantel treatment reduces worm burden followingSchistosoma mansonichallenge

(2013) Henrique K. Rofatto et al.   PeerJ

Virulence factors of schistosomes

(2012) R. Alan Wilson   MICROBES AND INFECTION

Cell Recruitment and Cytokines in Skin Mice Sensitized with the Vaccine Adjuvants: Saponin, Incomplete Freund’s Adjuvant, and Monophosphoryl Lipid A

(2012) Juliana Vitoriano-Souza et al.   PLoS One

Schistosoma mansoni Venom Allergen Like Proteins Present Differential Allergic Responses in a Murine Model of Airway Inflammation

(2012) Leonardo Paiva Farias et al.   PLoS Neglected Tropical Diseases

Early Patterns of Gene Expression Correlate With the Humoral Immune Response to Influenza Vaccination in Humans

(2011) Kristine L. Bucasas et al.   JOURNAL OF INFECTIOUS DISEASES

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts

(2010) R. DeMarco et al.   GENOME RESEARCH

Immunogenomics and systems biology of vaccines

(2010) Luigi Buonaguro et al.   IMMUNOLOGICAL REVIEWS

Expression of Genes Associated with Immunoproteasome Processing of Major Histocompatibility Complex Peptides Is Indicative of Protection with Adjuvanted RTS,S Malaria Vaccine

(2010) Maryanne T. Vahey et al.   JOURNAL OF INFECTIOUS DISEASES

Immune Events Associated with High Level Protection against Schistosoma japonicum Infection in Pigs Immunized with UV-Attenuated Cercariae

(2010) Fang Tian et al.   PLoS One

Molecular immune signatures of HIV-1 vaccines in human PBMCs

(2009) Alessandro Monaco et al.   FEBS LETTERS

Radiation-attenuated schistosome vaccination – a brief historical perspective

(2009) Q. D. BICKLE   PARASITOLOGY

The saga of schistosome migration and attrition

(2009) R. A. WILSON   PARASITOLOGY

Gene expression profile of peripheral blood mononuclear cells in response to HIV-VLPs stimulation

(2008) Luigi Buonaguro et al.   BMC BIOINFORMATICS

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY