The Role of Alpha 2 Macroglobulin in IgG-Aggregation and Chronic Activation of the Complement System in Patients With Chronic Lymphocytic Leukemia

Autoimmune Complications in Chronic Lymphocytic Leukemia in the Era of Targeted Drugs

(2020) Vitale et al.   Cancers

Cell-free IgG-aggregates in plasma of patients with chronic lymphocytic leukemia cause chronic activation of the classical complement pathway

(2020) Regina Michelis et al.   PLoS One

A C5a-Immunoglobulin complex in chronic lymphocytic leukemia patients is associated with decreased complement activity

(2019) Regina Michelis et al.   PLoS One

Unraveling the Macromolecular Pathways of IgG Oligomerization and Complement Activation on Antigenic Surfaces

(2019) Jürgen Strasser et al.   NANO LETTERS

Alpha-2-Macroglobulin, a Hypochlorite-Regulated Chaperone and Immune System Modulator

(2019) Jordan H. Cater et al.   Oxidative Medicine and Cellular Longevity

Association of GRP78, HIF-1α and BAG3 Expression with the Severity of Chronic Lymphocytic Leukemia

(2019) Roghayeh Ijabi et al.   Anti-Cancer Agents in Medicinal Chemistry

Unexpected cross-reactivity of anti-cathepsin B antibodies leads to uncertainties regarding the mechanism of action of anti-CD20 monoclonal antibody GA101

(2017) Wei Wen Chien et al.   LEUKEMIA RESEARCH

Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

(2017) Simon A. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions

(2016) Erika M. Cook et al.   JOURNAL OF IMMUNOLOGY

Regulatory B lymphocyte functions should be considered in chronic lymphocytic leukemia

(2016) Audrey Mohr et al.   OncoImmunology

Perturbation of the normal immune system in patients with CLL

(2015) F. Forconi et al.   BLOOD

Antibodies reactive to cleaved sites in complement proteins enable highly specific measurement of soluble markers of complement activation

(2015) Anna M. Blom et al.   MOLECULAR IMMUNOLOGY

Complement System Part I – Molecular Mechanisms of Activation and Regulation

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

Complement deficiencies limit CD20 monoclonal antibody treatment efficacy in CLL

(2014) O Middleton et al.   LEUKEMIA

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

(2014) C. A. Diebolder et al.   SCIENCE

Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding

(2012) Leticia Huergo-Zapico et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

(2011) Min Ni et al.   BIOCHEMICAL JOURNAL

The clinical application of monoclonal antibodies in chronic lymphocytic leukemia

(2010) S. M. Jaglowski et al.   BLOOD

Roles of GRP78 in physiology and cancer

(2010) Lu-Hua Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Complement and its role in innate and adaptive immune responses

(2009) Jason R Dunkelberger et al.   CELL RESEARCH

The Role of Complement in the Mechanism of Action of Rituximab for B-Cell Lymphoma: Implications for Therapy

(2008) X. Zhou et al.   ONCOLOGIST