Synthesis of Fusidic Acid Derivatives Yields a Potent Antibiotic with an Improved Resistance Profile

Pharmacokinetics and Organ Distribution of C-3 Alkyl Esters as Potential Antimycobacterial Prodrugs of Fusidic Acid

(2020) Natasha Strydom et al.   ACS Infectious Diseases

Prevalence and molecular characterization of methicillin-resistant Staphylococcus aureus with mupirocin, fusidic acid and/or retapamulin resistance

(2020) Wenjing Chen et al.   BMC MICROBIOLOGY

Fusidic acid resistance through changes in the dynamics of the drug target

(2020) Jennifer H. Tomlinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Semisynthetic Antimycobacterial C-3 Silicate and C-3/C-21 Ester Derivatives of Fusidic Acid: Pharmacological Evaluation and Stability Studies in Liver Microsomes, Rat Plasma, and Mycobacterium tuberculosis culture

(2019) Mathew Njoroge et al.   ACS Infectious Diseases

The rise in vancomycin-resistant Enterococcus faecium in Germany: data from the German Antimicrobial Resistance Surveillance (ARS)

(2019) Robby Markwart et al.   Antimicrobial Resistance and Infection Control

The global preclinical antibacterial pipeline

(2019) Ursula Theuretzbacher et al.   NATURE REVIEWS MICROBIOLOGY

In Vitro and In Vivo Activities of DS86760016, a Novel Leucyl-tRNA Synthetase Inhibitor for Gram-Negative Pathogens

(2018) Kedar P. Purnapatre et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Microbial Oxidation of the Fusidic Acid Side Chain by Cunninghamella echinulata

(2018) Abdel-Rahim Ibrahim et al.   MOLECULES

3D-QSAR Modeling and Synthesis of New Fusidic Acid Derivatives as Antiplasmodial Agents

(2018) Gurminder Kaur et al.   Journal of Chemical Information and Modeling

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis

(2018) Alessandro Cassini et al.   LANCET INFECTIOUS DISEASES

The biological evaluation of fusidic acid and its hydrogenation derivative as antimicrobial and anti-inflammatory agents

(2018) Pan-Pan Wu et al.   Infection and Drug Resistance

Investigation and Treatment of Fusidic Acid Resistance Among Methicillin-Resistant Staphylococcal Isolates from Egypt

(2017) Alaa Abouelfetouh et al.   Microbial Drug Resistance

Site-selective oxidation, amination and epimerization reactions of complex polyols enabled by transfer hydrogenation

(2017) Christopher K. Hill et al.   Nature Chemistry

Appropriate Targets for Antibacterial Drugs

(2016) Lynn L. Silver   Cold Spring Harbor Perspectives in Medicine

Fusidic Acid: A Bacterial Elongation Factor Inhibitor for the Oral Treatment of Acute and Chronic Staphylococcal Infections

(2016) Prabhavathi Fernandes   Cold Spring Harbor Perspectives in Medicine

Synthesis of fusidic acid bioisosteres as antiplasmodial agents and molecular docking studies in the binding site of elongation factor-G

(2015) Gurminder Kaur et al.   MedChemComm

Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid

(2012) G. Cox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fusidic acid resistance among clinical isolates of methicillin-resistant Staphylococcus aureus in a Taiwanese hospital

(2011) Chih-Ming Chen et al.   BMC MICROBIOLOGY

Pharmacokinetics and Safety of Single, Multiple, and Loading Doses of Fusidic Acid in Healthy Subjects

(2011) J. G. Still et al.   CLINICAL INFECTIOUS DISEASES

Spectrum of activity, mutation rates, synergistic interactions, and the effects of pH and serum proteins for fusidic acid (CEM-102)

(2010) Douglas J. Biedenbach et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Staphylococcus aureus elongation factor G - structure and analysis of a target for fusidic acid

(2010) Yang Chen et al.   FEBS Journal

Performance of Fusidic Acid (CEM-102) Susceptibility Testing Reagents: Broth Microdilution, Disk Diffusion, and Etest Methods as Applied toStaphylococcus aureus

(2010) Ronald N. Jones et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity

(2009) C. Oefner et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

(2009) Y.-G. Gao et al.   SCIENCE