Molecular Mechanisms Underlying Ascl1-Mediated Astrocyte-to-Neuron Conversion

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons

(2019) Chongyuan Luo et al.   eLife

Direct Neuronal Reprogramming Reveals Unknown Functions for Known Transcription Factors

(2019) Gaia Colasante et al.   Frontiers in Neuroscience

Conversion of Astrocytes and Fibroblasts into Functional Noradrenergic Neurons

(2019) Sanlan Li et al.   Cell Reports

Understanding direct neuronal reprogramming — from pioneer factors to 3D chromatin

(2018) Jovica Ninkovic et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts

(2018) Seong Won Lee et al.   DEVELOPMENTAL CELL

Directing neuronal cell fate in vitro : Achievements and challenges

(2018) R.J.M. Riemens et al.   PROGRESS IN NEUROBIOLOGY

Mechanistic Insights Into MicroRNA-Induced Neuronal Reprogramming of Human Adult Fibroblasts

(2018) Ya-Lin Lu et al.   Frontiers in Neuroscience

Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2

(2018) Roberta Pereira de Melo Guimarães et al.   Frontiers in Cellular Neuroscience

Binding of HMGN proteins to cell specific enhancers stabilizes cell identity

(2018) Bing He et al.   Nature Communications

KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes

(2018) Giulia Barbagiovanni et al.   Cell Reports

Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates

(2017) Moritz Mall et al.   NATURE

Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

(2017) Dinesh Manandhar et al.   NUCLEIC ACIDS RESEARCH

Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

(2017) Weijun Feng et al.   Nature Communications

Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons

(2017) Orly L. Wapinski et al.   Cell Reports

Lineage Reprogramming of Astroglial Cells from Different Origins into Distinct Neuronal Subtypes

(2017) Malek Chouchane et al.   Stem Cell Reports

Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells

(2016) Joshua B. Black et al.   Cell Stem Cell

Direct neuronal reprogramming: learning from and for development

(2016) Giacomo Masserdotti et al.   DEVELOPMENT

Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq

(2016) Barbara Treutlein et al.   NATURE

MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis

(2016) Francisca F. Vasconcelos et al.   Cell Reports

Tet3-Mediated DNA Demethylation Contributes to the Direct Conversion of Fibroblast to Functional Neuron

(2016) Juan Zhang et al.   Cell Reports

Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron Reprogramming

(2016) Derek K. Smith et al.   Stem Cell Reports

Direct Lineage Reprogramming: Strategies, Mechanisms, and Applications

(2015) Jun Xu et al.   Cell Stem Cell

Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming

(2015) Gaia Colasante et al.   Cell Stem Cell

Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes

(2015) Giacomo Masserdotti et al.   Cell Stem Cell

Forward engineering neuronal diversity using direct reprogramming

(2015) R. K. Tsunemoto et al.   EMBO JOURNAL

Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo

(2015) Y. Liu et al.   JOURNAL OF NEUROSCIENCE

Generation of functional human serotonergic neurons from fibroblasts

(2015) K C Vadodaria et al.   MOLECULAR PSYCHIATRY

Direct conversion of human fibroblasts to induced serotonergic neurons

(2015) Z Xu et al.   MOLECULAR PSYCHIATRY

Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis

(2015) Alexandre A.S.F. Raposo et al.   Cell Reports

The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro

(2014) F. R. Ali et al.   DEVELOPMENT

Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1

(2014) Soham Chanda et al.   Stem Cell Reports

Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons

(2013) Orly L. Wapinski et al.   CELL

The Chromatin Remodeler CHD7 Regulates Adult Neurogenesis via Activation of SoxC Transcription Factors

(2013) Weijun Feng et al.   Cell Stem Cell

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

(2013) Ziyuan Guo et al.   Cell Stem Cell

ASCL1 reprograms mouse Muller glia into neurogenic retinal progenitors

(2013) J. Pollak et al.   DEVELOPMENT

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

(2013) Wenze Niu et al.   NATURE CELL BIOLOGY

Generation of induced neurons via direct conversion in vivo

(2013) O. Torper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons

(2013) Meng-Lu Liu et al.   Nature Communications

Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts

(2011) Jongpil Kim et al.   Cell Stem Cell

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

(2011) Esther Y. Son et al.   Cell Stem Cell

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

(2011) Massimiliano Caiazzo et al.   NATURE

Efficient Conversion of Astrocytes to Functional Midbrain Dopaminergic Neurons Using a Single Polycistronic Vector

(2011) Russell C. Addis et al.   PLoS One

Direct conversion of human fibroblasts to dopaminergic neurons

(2011) U. Pfisterer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons

(2010) Christophe Heinrich et al.   PLOS BIOLOGY

Different Transcription Factors RegulatenestinGene Expression during P19 Cell Neural Differentiation and Central Nervous System Development

(2009) Zhigang Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY