EpiMOGA: An Epistasis Detection Method Based on a Multi-Objective Genetic Algorithm

Shared genetic architecture between metabolic traits and Alzheimer’s disease: a large-scale genome-wide cross-trait analysis

(2019) Zhaozhong Zhu et al.   HUMAN GENETICS

Genome-wide RNA sequencing analysis reveals that IGF-2 attenuates memory decline, oxidative stress and amyloid plaques in an Alzheimer’s disease mouse model (AD) by activating the PI3K/AKT/CREB signaling pathway

(2019) Lei Xia et al.   INTERNATIONAL PSYCHOGERIATRICS

Epi-GTBN: an approach of epistasis mining based on genetic Tabu algorithm and Bayesian network

(2019) Yang Guo et al.   BMC BIOINFORMATICS

Expression and functional characterization of missense mutations in ATP8A2 linked to severe neurological disorders

(2019) Hanbin Choi et al.   HUMAN MUTATION

Loss of the fragile X mental retardation protein causes aberrant differentiation in human neural progenitor cells

(2018) Naohiro Sunamura et al.   Scientific Reports

FDHE-IW: A Fast Approach for Detecting High-Order Epistasis in Genome-Wide Case-Control Studies

(2018) Shouheng Tuo   Genes

FRMPD4 mutations cause X-linked intellectual disability and disrupt dendritic spine morphogenesis

(2017) Juliette Piard et al.   HUMAN MOLECULAR GENETICS

epiACO - a method for identifying epistasis based on ant Colony optimization algorithm

(2017) Yingxia Sun et al.   BioData Mining

Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis

(2016) Yongping Zhang et al.   MOLECULAR CELL

New ATP8A2 gene mutations associated with a novel syndrome: encephalopathy, intellectual disability, severe hypotonia, chorea and optic atrophy

(2016) Elena Martín-Hernández et al.   NEUROGENETICS

Potential of GRID2 receptor gene for preventing TNF-induced neurodegeneration in autism

(2016) Zeynep Kalkan et al.   NEUROSCIENCE LETTERS

FHSA-SED: Two-Locus Model Detection for Genome-Wide Association Study with Harmony Search Algorithm

(2016) Shouheng Tuo et al.   PLoS One

Functional Regression Models for Epistasis Analysis of Multiple Quantitative Traits

(2016) Futao Zhang et al.   PLoS Genetics

Detecting gene-gene interactions using a permutation-based random forest method

(2016) Jing Li et al.   BioData Mining

Do Copy Number Changes in CACNA2D2, CACNA2D3, and CACNA1D Constitute a Predisposing Risk Factor for Alzheimer’s Disease?

(2016) Darine Villela et al.   Frontiers in Genetics

Absent CNKSR2 causes seizures and intellectual, attention, and language deficits

(2014) Andrea K. Vaags et al.   ANNALS OF NEUROLOGY

MACOED: a multi-objective ant colony optimization algorithm for SNP epistasis detection in genome-wide association studies

(2014) Peng-Jie Jing et al.   BIOINFORMATICS

Pathological Reorganization of NMDA Receptors Subunits and Postsynaptic Protein PSD-95 Distribution in Alzheimer’s Disease

(2014) Genevieve Leuba et al.   Current Alzheimer Research

AprioriGWAS, a New Pattern Mining Strategy for Detecting Genetic Variants Associated with Disease through Interaction Effects

(2014) Qingrun Zhang et al.   PLoS Computational Biology

G Proteins, p60TRP, and Neurodegenerative Diseases

(2013) Klaus Heese   MOLECULAR NEUROBIOLOGY

Brain-Site-Specific Proteome Changes Induced by Neuronal P60TRP Expression

(2013) Arulmani Manavalan et al.   NEUROSIGNALS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Quantifying Missing Heritability at Known GWAS Loci

(2013) Alexander Gusev et al.   PLoS Genetics

A gene trap knockout of the Tiam-1 protein results in malformation of the early embryonic brain

(2012) Sooyeon Yoo et al.   MOLECULES AND CELLS

GAMETES: a fast, direct algorithm for generating pure, strict, epistatic models with random architectures

(2012) Ryan J Urbanowicz et al.   BioData Mining

BOOST: A Fast Approach to Detecting Gene-Gene Interactions in Genome-wide Case-Control Studies

(2010) Xiang Wan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Missing heritability and strategies for finding the underlying causes of complex disease

(2010) Evan E. Eichler et al.   NATURE REVIEWS GENETICS

Predictive rule inference for epistatic interaction detection in genome-wide association studies

(2009) Xiang Wan et al.   BIOINFORMATICS

CAZIP, a novel protein expressed in the developing heart and nervous system

(2009) Leonie Du Puy et al.   DEVELOPMENTAL DYNAMICS

Expanded clinical phenotype of women with theFMR1 premutation

(2008) Sarah M. Coffey et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A support vector machine approach for detecting gene-gene interaction

(2007) Shyh-Huei Chen et al.   GENETIC EPIDEMIOLOGY