Effect of spexin on renal dysfunction in experimentally obese rats: potential mitigating mechanisms via galanin receptor-2

Mitigation of renal inflammation and endoplasmic reticulum stress by vildagliptin and statins in high-fat high-fructose diet-induced insulin resistance and renal injury in rats

(2020) Laongdao Thongnak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Obesity, kidney dysfunction and hypertension: mechanistic links

(2019) John E. Hall et al.   Nature Reviews Nephrology

Quercetin Inhibits the Production of IL-1β-Induced Inflammatory Cytokines and Chemokines in ARPE-19 Cells via the MAPK and NF-κB Signaling Pathways

(2019) Shu-Chen Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diacerein alleviates kidney injury through attenuating inflammation and oxidative stress in obese insulin-resistant rats

(2018) Nuttawud Chueakula et al.   FREE RADICAL BIOLOGY AND MEDICINE

Spexin Acts as Novel Regulator for Bile Acid Synthesis

(2018) Cheng-yuan Lin et al.   Frontiers in Physiology

Central galanin receptor 2 mediates galanin action to promote systemic glucose metabolism of type 2 diabetic rats

(2018) Penghua Fang et al.   BIOCHEMICAL PHARMACOLOGY

Spexin: A novel regulator of adipogenesis and fat tissue metabolism

(2018) Pawel A. Kolodziejski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Spexin Levels Are Associated with Metabolic Syndrome Components

(2018) Nasser M. Al-Daghri et al.   DISEASE MARKERS

High-fructose in drinking water initiates activation of inflammatory cytokines and testicular degeneration in rat

(2018) Onur Gökhan Yildirim et al.   TOXICOLOGY MECHANISMS AND METHODS

Inflammatory Links Between High Fat Diets and Diseases

(2018) Yehui Duan et al.   Frontiers in Immunology

Chronic Fructose Ingestion as a Major Health Concern: Is a Sedentary Lifestyle Making It Worse? A Review

(2017) Amy Bidwell   Nutrients

High Dietary Fructose: Direct or Indirect Dangerous Factors Disturbing Tissue and Organ Functions

(2017) Dong-Mei Zhang et al.   Nutrients

Metabolic Syndrome and Hypertension Resulting from Fructose Enriched Diet in Wistar Rats

(2017) Julie Dupas et al.   Biomed Research International

The Implication of PGC-1α on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues

(2017) Elżbieta Supruniuk et al.   Frontiers in Physiology

Oxidant Mechanisms in Renal Injury and Disease

(2016) Brian B. Ratliff et al.   ANTIOXIDANTS & REDOX SIGNALING

High-fructose and high-fat diet-induced disorders in rats: impact on diabetes risk, hepatic and vascular complications

(2016) Iona Lozano et al.   Nutrition & Metabolism

Development of Spexin-based Human Galanin Receptor Type II-Specific Agonists with Increased Stability in Serum and Anxiolytic Effect in Mice

(2016) Arfaxad Reyes-Alcaraz et al.   Scientific Reports

High-fructose and high-fat diet-induced insulin resistance enhances atherosclerosis in Watanabe heritable hyperlipidemic rabbits

(2015) Bo Ning et al.   Nutrition & Metabolism

Histologic and Metabolic Derangement in High-Fat, High-Fructose, and Combination Diet Animal Models

(2015) Jai Sun Lee et al.   TheScientificWorldJOURNAL

Spexin Enhances Bowel Movement through Activating L-type Voltage-dependent Calcium Channel via Galanin Receptor 2 in Mice

(2015) Cheng-yuan Lin et al.   Scientific Reports

Histologic and Metabolic Derangement in High-Fat, High-Fructose, and Combination Diet Animal Models

(2015) Jai Sun Lee et al.   Scientific World Journal

Renal Klotho expression in patients with acute kidney injury is associated with the severity of the injury

(2015) Min Young Seo et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities

(2015) Chen Yu et al.   Scientific Reports

Coevolution of the Spexin/Galanin/Kisspeptin Family: Spexin Activates Galanin Receptor Type II and III

(2014) Dong-Kyu Kim et al.   ENDOCRINOLOGY

Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity

(2014) José L. Walewski et al.   Obesity

Evaluation of Growth Patterns and Body Composition in C57Bl/6J Mice Using Dual Energy X-Ray Absorptiometry

(2014) Sara Gargiulo et al.   Biomed Research International

Peptides derived from the prohormone proNPQ/spexin are potent central modulators of cardiovascular and renal function and nociception

(2011) Lawrence Toll et al.   FASEB JOURNAL