Laboratory Diagnostic Tools for Syphilis: Current Status and Future Prospects

Chemokine Ligand 13 (CXCL13) in Neuroborreliosis and Neurosyphilis as Selected Spirochetal Neurological Diseases: A Review of Its Diagnostic Significance

(2020) Monika Gudowska-Sawczuk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Syphilis Laboratory Guidelines: Performance Characteristics of Nontreponemal Antibody Tests

(2020) Susan Tuddenham et al.   CLINICAL INFECTIOUS DISEASES

Molecular and Direct Detection Tests for Treponema pallidum Subspecies pallidum: A Review of the Literature, 1964–2017

(2020) Elitza S Theel et al.   CLINICAL INFECTIOUS DISEASES

The Traditional or Reverse Algorithm for Diagnosis of Syphilis: Pros and Cons

(2020) Daniel A Ortiz et al.   CLINICAL INFECTIOUS DISEASES

Sensitivity and Specificity of Treponemal-specific Tests for the Diagnosis of Syphilis

(2020) Ina U Park et al.   CLINICAL INFECTIOUS DISEASES

Cerebrospinal Fluid Cytokines in Patients with Neurosyphilis: The Significance of Interleukin-10 for the Disease

(2020) Wurong Li et al.   Biomed Research International

Syphilis: A great imitator

(2019) Seray Külcü Çakmak et al.   CLINICS IN DERMATOLOGY

Exosomal microRNA profiles from serum and cerebrospinal fluid in neurosyphilis

(2019) Huan Chen et al.   SEXUALLY TRANSMITTED INFECTIONS

Sexually Acquired Syphilis. Part 2: Laboratory diagnosis, management, and prevention

(2019) Amy K. Forrestel et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Are non-treponemal tests suitable for monitoring syphilis treatment Efficacy? Evidence from rabbit infection models

(2019) L.-R. Lin et al.   CLINICAL MICROBIOLOGY AND INFECTION

Neurosyphilis

(2019) Hemil Gonzalez et al.   SEMINARS IN NEUROLOGY

Performance of treponemal tests for the diagnosis of syphilis

(2018) Ina U Park et al.   CLINICAL INFECTIOUS DISEASES

Treponema pallidum Immunohistochemistry is positive in human intestinal Spirochetosis

(2018) Rondell P. Graham et al.   Diagnostic Pathology

Origin of Nontreponemal Antibodies During Treponema pallidum Infection: Evidence From a Rabbit Model

(2018) Kun Gao et al.   JOURNAL OF INFECTIOUS DISEASES

Neurosyphilis

(2018) Susan Tuddenham et al.   SEXUALLY TRANSMITTED DISEASES

Reported Primary and Secondary Syphilis Cases in the United States

(2018) Sarah Kidd et al.   SEXUALLY TRANSMITTED DISEASES

Long-Term In Vitro Culture of the Syphilis Spirochete Treponema pallidum subsp. pallidum

(2018) Diane G. Edmondson et al.   mBio

Sensitive detection of Treponema pallidum DNA from the whole blood of patients with syphilis by the nested PCR assay

(2018) Cuini Wang et al.   Emerging Microbes & Infections

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR

(2018) Melanie K. B. Wills et al.   Jove-Journal of Visualized Experiments

Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination

(2018) Wen Liu et al.   CLINICA CHIMICA ACTA

Candidate Treponema pallidum biomarkers uncovered in urine from individuals with syphilis using mass spectrometry

(2018) Kara K Osbak et al.   Future Microbiology

Development of a sensitive PCR-dot blot assay to supplement serological tests for diagnosing Lyme disease

(2017) J. S. Shah et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Cerebrospinal Fluid Treponema pallidum Particle Agglutination Assay for Neurosyphilis Diagnosis

(2017) Christina M. Marra et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Sensitivity of nPCR for four types of membrane protein DNA and of two pairs of primers for Tpp47 DNA of Treponema pallidum in whole blood of congenital syphilis newborns

(2017) Yafei Guan et al.   Journal of Maternal-Fetal & Neonatal Medicine

Identification of Mycobacterium tuberculosis in Clinical Specimens of Patients Suspected of Having Extrapulmonary Tuberculosis by Application of Nested PCR on Five Different Genes

(2017) Azar D. Khosravi et al.   Frontiers in Cellular and Infection Microbiology

Syphilis

(2017) Rosanna W. Peeling et al.   Nature Reviews Disease Primers

Serological Response Predicts Normalization of Cerebrospinal Fluid Abnormalities at Six Months after Treatment in HIV-Negative Neurosyphilis Patients

(2017) Yao Xiao et al.   Scientific Reports

Clinical and Biological Characteristics of 40 Patients With Neurosyphilis and Evaluation ofTreponema pallidumNested Polymerase Chain Reaction in Cerebrospinal Fluid Samples

(2016) Clélia Vanhaecke et al.   CLINICAL INFECTIOUS DISEASES

Detection ofTreponema pallidumSp.PallidumDNA in Cerebrospinal Fluid (CSF) by Two PCR Techniques

(2016) Rita Castro et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

A negative nontreponemal and/or specific antitreponemal IgM test does not exclude active infectious syphilis

(2016) Li-Rong Lin et al.   MEDICINE

Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen

(2016) Justin D. Radolf et al.   NATURE REVIEWS MICROBIOLOGY

Evaluation of Treponemal Serum Tests Performed on Cerebrospinal Fluid for Diagnosis of Neurosyphilis

(2015) Jeannette Guarner et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Canadian Public Health Laboratory Network Laboratory Guidelines for the Use of Direct Tests to Detect Syphilis in Canada

(2015) Raymond SW Tsang et al.   Canadian Journal of Infectious Diseases & Medical Microbiology

Incidental Syphilis Diagnosed by Real-Time PCR Screening of Urine Samples: TABLE 1

(2015) Grégory Dubourg et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation of the Boson Chemiluminescence Immunoassay as a First-Line Screening Test in the ECDC Algorithm for Syphilis Serodiagnosis in a Population with a High Prevalence of Syphilis

(2015) Xin-Hui Qiu et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparison of Diagnostic Accuracy of PCR Targeting the 47-Kilodalton Protein Membrane Gene of Treponema pallidum and PCR Targeting the DNA Polymerase I Gene: Systematic Review and Meta-analysis

(2015) Angèle Gayet-Ageron et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Detection of urinary biomarkers in reservoir hosts of leptospirosis by capillary electrophoresis-mass spectrometry

(2015) Jarlath E. Nally et al.   Proteomics Clinical Applications

Flagellar motility of the pathogenic spirochetes

(2015) Charles W. Wolgemuth   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MALDI-TOF mass spectrometry: an emerging technology for microbial identification and diagnosis

(2015) Neelja Singhal et al.   Frontiers in Microbiology

Recent Trends in the Serologic Diagnosis of Syphilis

(2014) Muhammad G. Morshed et al.   Clinical and Vaccine Immunology

Analysis of 3 Algorithms for Syphilis Serodiagnosis and Implications for Clinical Management

(2014) M.-L. Tong et al.   CLINICAL INFECTIOUS DISEASES

2014 European guideline on the management of syphilis

(2014) M. Janier et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Evaluation of Loop-Mediated Isothermal Amplification Suitable for Molecular Monitoring of Schistosome-Infected Snails in Field Laboratories

(2012) Joseph Hamburger et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A longitudinal evaluation of Treponema pallidumPCR testing in early syphilis

(2012) Matt Shields et al.   BMC INFECTIOUS DISEASES

Evaluation of a PCR Test for Detection of Treponema pallidum in Swabs and Blood

(2012) P. A. Grange et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The Rapid Plasma Reagin Test Cannot Replace the Venereal Disease Research Laboratory Test for Neurosyphilis Diagnosis

(2012) Christina M. Marra et al.   SEXUALLY TRANSMITTED DISEASES

Sensitivity, specificity and likelihood ratios of PCR in the diagnosis of syphilis: a systematic review and meta-analysis

(2012) Angèle Gayet-Ageron et al.   SEXUALLY TRANSMITTED INFECTIONS

Comparative analysis of immunohistochemistry, polymerase chain reaction and focus-floating microscopy for the detection of Treponema pallidum in mucocutaneous lesions of primary, secondary and tertiary syphilis

(2011) H. Müller et al.   BRITISH JOURNAL OF DERMATOLOGY

Getting the measure of syphilis: qPCR to better understand early infection

(2011) C. Tipple et al.   SEXUALLY TRANSMITTED INFECTIONS

Comparative Diagnosis of Malaria Infections by Microscopy, Nested PCR, and LAMP in Northern Thailand

(2010) Birgit Pöschl et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

NovelTreponema pallidumSerologic Tests: A Paradigm Shift in Syphilis Screening for the 21st Century

(2010) Arlene C. Seña et al.   CLINICAL INFECTIOUS DISEASES

Lumbar Puncture in HIV‐Infected Patients with Syphilis and No Neurologic Symptoms

(2009) Khalil G. Ghanem et al.   CLINICAL INFECTIOUS DISEASES

Clinical Value of Treponema pallidum Real-Time PCR for Diagnosis of Syphilis

(2009) R. Heymans et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The Architect Syphilis assay for antibodies to Treponema pallidum: an automated screening assay with high sensitivity in primary syphilis

(2008) H Young et al.   SEXUALLY TRANSMITTED INFECTIONS