Genome-wide dissection reveals diverse pathogenic roles of bacterial Tc toxins

Interactive Tree Of Life (iTOL) v4: recent updates and new developments

(2019) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

A Bacterial Phage Tail-like Structure Kills Eukaryotic Cells by Injecting a Nuclease Effector

(2019) Iara Rocchi et al.   Cell Reports

Tc Toxin Complexes: Assembly, Membrane Permeation, and Protein Translocation

(2019) Daniel Roderer et al.   Annual Review of Microbiology

The Photorhabdus asymbiotica virulence cassettes deliver protein effectors directly into target eukaryotic cells

(2019) Isabella Vlisidou et al.   eLife

CDD/SPARCLE: the conserved domain database in 2020

(2019) Shennan Lu et al.   NUCLEIC ACIDS RESEARCH

Structure of a Tc holotoxin pore provides insights into the translocation mechanism

(2019) Daniel Roderer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards the application of Tc toxins as a universal protein translocation system

(2019) Daniel Roderer et al.   Nature Communications

The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology

(2019) Thomas E. Wood et al.   Cell Reports

Genome-wide Identification and Characterization of a Superfamily of Bacterial Extracellular Contractile Injection Systems

(2019) Lihong Chen et al.   Cell Reports

Common architecture of Tc toxins from human and insect pathogenic bacteria

(2019) F. Leidreiter et al.   Science Advances

The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny, and Escherichia core genomic diversity

(2019) Zhemin Zhou et al.   GENOME RESEARCH

Protein-Injection Machines in Bacteria

(2018) Jorge E. Galán et al.   CELL

GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens

(2018) Zhemin Zhou et al.   GENOME RESEARCH

Tc toxin activation requires unfolding and refolding of a β-propeller

(2018) Christos Gatsogiannis et al.   NATURE

VFDB 2019: a comparative pathogenomic platform with an interactive web interface

(2018) Bo Liu et al.   NUCLEIC ACIDS RESEARCH

PAAR-Rhs proteins harbor various C-terminal toxins to diversify the antibacterial pathways of type VI secretion systems

(2017) Jiale Ma et al.   ENVIRONMENTAL MICROBIOLOGY

Of guards, decoys, baits and traps: pathogen perception in plants by type III effector sensors

(2016) Madiha Khan et al.   CURRENT OPINION IN MICROBIOLOGY

Salmonella enterica: Survival, Colonization, and Virulence Differences among Serovars

(2015) A. Andino et al.   TheScientificWorldJOURNAL

New Players in the Toxin Field: Polymorphic Toxin Systems in Bacteria

(2015) Anne Jamet et al.   mBio

A New Family of Secreted Toxins in Pathogenic Neisseria Species

(2015) Anne Jamet et al.   PLoS Pathogens

Phylogeography of Yersinia ruckeri reveals effects of past evolutionary events on the current strain distribution and explains variations in the global transmission of enteric redmouth (ERM) disease

(2015) Asmine Bastardo et al.   Frontiers in Microbiology

Salmonella enterica: Survival, Colonization, and Virulence Differences among Serovars

(2015) A. Andino et al.   Scientific World Journal

Compact graphical representation of phylogenetic data and metadata with GraPhlAn

(2015) Francesco Asnicar et al.   PeerJ

Homologues of insecticidal toxin complex genes within a genomic island in the marine bacteriumVibrio parahaemolyticus

(2014) Kathy F.J. Tang et al.   FEMS MICROBIOLOGY LETTERS

Genetically distinct pathways guide effector export through the type VI secretion system

(2014) John C. Whitney et al.   MOLECULAR MICROBIOLOGY

Mechanism of Tc toxin action revealed in molecular detail

(2014) Dominic Meusch et al.   NATURE

Parallel independent evolution of pathogenicity within the genus Yersinia

(2014) S. Reuter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of an Insecticidal Toxin and Pathogenicity of Pseudomonas taiwanensis against Insects

(2014) Wen-Jen Chen et al.   PLoS Pathogens

Role of Yersinia pestis Toxin Complex Family Proteins in Resistance to Phagocytosis by Polymorphonuclear Leukocytes

(2013) Justin L. Spinner et al.   INFECTION AND IMMUNITY

The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device

(2013) Jason N. Busby et al.   NATURE

A syringe-like injection mechanism in Photorhabdus luminescens toxins

(2013) Christos Gatsogiannis et al.   NATURE

Challenges in homology search: HMMER3 and convergent evolution of coiled-coil regions

(2013) Jaina Mistry et al.   NUCLEIC ACIDS RESEARCH

Rhs proteins from diverse bacteria mediate intercellular competition

(2013) S. Koskiniemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

(2012) Dapeng Zhang et al.   Biology Direct

Yersinia pestis insecticidal-like toxin complex (Tc) family proteins: characterization of expression, subcellular localization, and potential role in infection of the flea vector

(2012) Justin L Spinner et al.   BMC MICROBIOLOGY

Ribosomal multilocus sequence typing: universal characterization of bacteria from domain to strain

(2012) K. A. Jolley et al.   MICROBIOLOGY-SGM

The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems

(2012) Sophie S. Abby et al.   PLoS Genetics

Yersinia enterocolitica: Pathogenesis, virulence and antimicrobial resistance

(2011) Anna Fàbrega et al.   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

The Main Virulence Determinant of Yersinia entomophaga MH96 Is a Broad-Host-Range Toxin Complex Active against Insects

(2011) M. R. H. Hurst et al.   JOURNAL OF BACTERIOLOGY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Bacterial protein toxins that modify host regulatory GTPases

(2011) Klaus Aktories   NATURE REVIEWS MICROBIOLOGY

3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activity

(2011) M. J. Landsberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria

(2010) Stephanie K. Aoki et al.   NATURE

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

Photorhabdus luminescens Toxins ADP-Ribosylate Actin and RhoA to Force Actin Clustering

(2010) A. E. Lang et al.   SCIENCE

Evolutionary diversification of an ancient gene family (rhs) through C-terminal displacement

(2009) Andrew P Jackson et al.   BMC GENOMICS

Common Themes in the Design and Function of Bacterial Effectors

(2009) Jorge E. Galán   Cell Host & Microbe

Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin

(2009) P. G. Leiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insecticidal genes of Yersinia spp.: taxonomical distribution, contribution to toxicity towards Manduca sexta and Galleria mellonella, and evolution

(2008) Thilo M Fuchs et al.   BMC MICROBIOLOGY

Comparative genomics: the bacterial pan-genome

(2008) Hervé Tettelin et al.   CURRENT OPINION IN MICROBIOLOGY

The Yersinia pseudotuberculosis and Yersinia pestis toxin complex is active against cultured mammalian cells

(2008) M. C. Hares et al.   MICROBIOLOGY-SGM

The All-Species Living Tree project: A 16S rRNA-based phylogenetic tree of all sequenced type strains

(2008) Pablo Yarza et al.   SYSTEMATIC AND APPLIED MICROBIOLOGY