Rapamycin inhibits pathogen transmission in mosquitoes by promoting immune activation

Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission

(2019) Douglas G. Paton et al.   NATURE

Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles

(2019) Kristine Werling et al.   CELL

CRISPR/Cas9 -mediated gene knockout of Anopheles gambiae FREP1 suppresses malaria parasite infection

(2018) Yuemei Dong et al.   PLoS Pathogens

PGRP-LD mediates A. stephensi vector competency by regulating homeostasis of microbiota-induced peritrophic matrix synthesis

(2018) Xiumei Song et al.   PLoS Pathogens

TheAnopheles gambiaetranscriptome - a turning point for malaria control

(2017) A. Domingos et al.   INSECT MOLECULAR BIOLOGY

Acute Dietary Restriction Acts via TOR, PP2A, and Myc Signaling to Boost Innate Immunity in Drosophila

(2017) Jung-Eun Lee et al.   Cell Reports

NF-κB-Like Signaling Pathway REL2 in Immune Defenses of the Malaria Vector Anopheles gambiae

(2017) Suzana Zakovic et al.   Frontiers in Cellular and Infection Microbiology

Apolipophorin-III Acts as a Positive Regulator of Plasmodium Development in Anopheles stephensi

(2017) Rini Dhawan et al.   Frontiers in Physiology

Two insulin-like peptides differentially regulate malaria parasite infection in the mosquito through effects on intermediary metabolism

(2016) J. E. Pietri et al.   BIOCHEMICAL JOURNAL

Amino acids trigger down-regulation of superoxide via TORC pathway in the midgut of Rhodnius prolixus

(2016) A. C. P. Gandara et al.   BIOSCIENCE REPORTS

Fission Yeast SCYL1/2 Homologue Ppk32: A Novel Regulator of TOR Signalling That Governs Survival during Brefeldin A Induced Stress to Protein Trafficking

(2016) Katarzyna M. Kowalczyk et al.   PLoS Genetics

Plasmodium falciparum suppresses the host immune response by inducing the synthesis of insulin-like peptides (ILPs) in the mosquito Anopheles stephensi

(2015) Jose E. Pietri et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Inhibiting the Mammalian Target of Rapamycin Blocks the Development of Experimental Cerebral Malaria

(2015) Emile B. Gordon et al.   mBio

Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression

(2015) Pedro Mejia et al.   Nature Communications

Rapamycin: One Drug, Many Effects

(2014) Jing Li et al.   Cell Metabolism

Plasmodium falciparum Infection Increases Anopheles gambiae Attraction to Nectar Sources and Sugar Uptake

(2014) Vincent O. Nyasembe et al.   CURRENT BIOLOGY

Ovary ecdysteroidogenic hormone functions independently of the insulin receptor in the yellow fever mosquito, Aedes aegypti

(2013) Animesh Dhara et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

TheAnophelesInnate Immune System in the Defense against Malaria Infection

(2013) April M. Clayton et al.   Journal of Innate Immunity

Malaria Infected Mosquitoes Express Enhanced Attraction to Human Odor

(2013) Renate C. Smallegange et al.   PLoS One

Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins

(2013) K. K. Hanson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amino Acid Signaling in TOR Activation

(2011) Joungmok Kim et al.   Annual Review of Biochemistry

Nutritional and hormonal regulation of the TOR effector 4E-binding protein (4E-BP) in the mosquito Aedes aegypti

(2011) Saurabh G. Roy et al.   FASEB JOURNAL

Autophagy in parasitic protists: Unique features and drug targets

(2011) Ana Brennand et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Insulin-Like Peptides and the Target of Rapamycin Pathway Coordinately Regulate Blood Digestion and Egg Maturation in the Mosquito Aedes aegypti

(2011) Monika Gulia-Nuss et al.   PLoS One

The Major Yolk Protein Vitellogenin Interferes with the Anti-Plasmodium Response in the Malaria Mosquito Anopheles gambiae

(2010) Martin K. Rono et al.   PLOS BIOLOGY

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Implication of the Mosquito Midgut Microbiota in the Defense against Malaria Parasites

(2009) Yuemei Dong et al.   PLoS Pathogens

TOR signaling is required for amino acid stimulation of early trypsin protein synthesis in the midgut of Aedes aegypti mosquitoes

(2008) Michelle C. Brandon et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Nutrient content of diet affects the signaling activity of the insulin/target of rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiae

(2008) Dany Arsic et al.   JOURNAL OF INSECT PHYSIOLOGY