Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth
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Title
Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth
Authors
Keywords
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Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-03-04
DOI
10.1038/s41598-021-84443-y
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Note: Only part of the references are listed.- Overexpression of alpha-synuclein promotes both cell proliferation and cell toxicity in human SH-SY5Y neuroblastoma cells
- (2020) Noela Rodríguez-Losada et al. Journal of Advanced Research
- Parkinson's: A Disease of Aberrant Vesicle Trafficking
- (2020) Pawan Kishor Singh et al. Annual Review of Cell and Developmental Biology
- Unroofing site-specific α-synuclein–lipid interactions at the plasma membrane
- (2020) Upneet Kaur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Silencing of Synuclein-γ inhibits human cervical cancer through the AKT signaling pathway
- (2019) Chunnian Zhang et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Alpha-synuclein inhibits Snx3–retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson’s disease
- (2018) Dhaval Patel et al. HUMAN MOLECULAR GENETICS
- Extracellular gamma-synuclein promotes tumor cell motility by activating β1 integrin-focal adhesion kinase signaling pathway and increasing matrix metalloproteinase-24, -2 protein secretion
- (2018) Caiyun Liu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Parkinson’s Disease and Melanoma: Co-Occurrence and Mechanisms
- (2018) Anindita Bose et al. Journal of Parkinsons Disease
- Iron and Cancer
- (2018) Suzy V. Torti et al. Annual Review of Nutrition
- Cytochrome C oxidase Inhibition and Cold Plasma-derived Oxidants Synergize in Melanoma Cell Death Induction
- (2018) Rajesh Kumar Gandhirajan et al. Scientific Reports
- Diagnostic histochemistry in hepatic pathology
- (2018) Julia C. Iezzoni SEMINARS IN DIAGNOSTIC PATHOLOGY
- α-Synuclein promotes dilation of the exocytotic fusion pore
- (2017) Todd Logan et al. NATURE NEUROSCIENCE
- Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death
- (2017) Elisa Turriani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin
- (2017) Fan Yang et al. Oncotarget
- The Synucleinopathies: Twenty Years On
- (2017) Michel Goedert et al. Journal of Parkinsons Disease
- Synucleins and Gene Expression: Ramblers in a Crowd or Cops Regulating Traffic?
- (2017) Alexei A. Surguchev et al. Frontiers in Molecular Neuroscience
- Cutaneous malignant melanoma and Parkinson disease: Common pathways?
- (2016) Rivka Inzelberg et al. ANNALS OF NEUROLOGY
- Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson's disease
- (2016) Shounak Baksi et al. FREE RADICAL BIOLOGY AND MEDICINE
- Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics
- (2016) Abdel A. Belaidi et al. JOURNAL OF NEUROCHEMISTRY
- Ironing out Ferroportin
- (2015) Hal Drakesmith et al. Cell Metabolism
- Molecular mechanisms of non-transferrin-bound and transferring-bound iron uptake in primary hippocampal neurons
- (2015) Changyi Ji et al. JOURNAL OF NEUROCHEMISTRY
- Parkinson's disease
- (2015) Lorraine V Kalia et al. LANCET
- Unconventional secretion of synuclein-γ promotes tumor cell invasion
- (2014) Caiyun Liu et al. FEBS Journal
- 100 years of Lewy pathology
- (2012) Michel Goedert et al. Nature Reviews Neurology
- The Role of Alpha-Synuclein in Melanin Synthesis in Melanoma and Dopaminergic Neuronal Cells
- (2012) Tianhong Pan et al. PLoS One
- -Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2
- (2012) S. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H ß-synuclein
- (2012) Akio Sekigawa et al. Molecular Brain
- The association between Parkinson's disease and melanoma
- (2011) Tianhong Pan et al. INTERNATIONAL JOURNAL OF CANCER
- Lipocalin-2 Induces Cardiomyocyte Apoptosis by Increasing Intracellular Iron Accumulation
- (2011) Guoxiong Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding
- (2011) Iwona M. Pranke et al. JOURNAL OF CELL BIOLOGY
- α-Synuclein Expression Selectively Affects Tumorigenesis in Mice Modeling Parkinson's Disease
- (2011) Eitan Israeli et al. PLoS One
- Association of α-, β-, and γ-Synuclein With Diffuse Lewy Body Disease
- (2010) Kenya Nishioka et al. ARCHIVES OF NEUROLOGY
- Increased Melanoma Risk in Parkinson Disease
- (2010) John M. Bertoni ARCHIVES OF NEUROLOGY
- Parkinson's Disease-Related Protein, α-Synuclein, in Malignant Melanoma
- (2010) Yasuhiro Matsuo et al. PLoS One
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- Family history of melanoma and Parkinson disease risk
- (2009) X. Gao et al. NEUROLOGY
- GATA transcription factors directly regulate the Parkinson's disease-linked gene -synuclein
- (2008) C. R. Scherzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-Synuclein and Polyunsaturated Fatty Acids Promote Clathrin-Mediated Endocytosis and Synaptic Vesicle Recycling
- (2008) Tziona Ben Gedalya et al. TRAFFIC
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