Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1

The Application of Porphyrins and Their Analogues for Inactivation of Viruses

(2020) Natalya Sh. Lebedeva et al.   MOLECULES

Conserved G-Quadruplexes Regulate the Immediate Early Promoters of Human Alphaherpesviruses

(2019) Ilaria Frasson et al.   MOLECULES

LANA and hnRNP A1 regulate the translation of LANA mRNA through G-quadruplexes

(2019) Prerna Dabral et al.   JOURNAL OF VIROLOGY

Streamlining effects of extra telomeric repeat on telomeric DNA folding revealed by fluorescence-force spectroscopy

(2019) Jaba Mitra et al.   NUCLEIC ACIDS RESEARCH

I-motif DNA structures are formed in the nuclei of human cells

(2018) Mahdi Zeraati et al.   Nature Chemistry

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy

(2018) Emanuela Ruggiero et al.   NUCLEIC ACIDS RESEARCH

i-Motif DNA: structural features and significance to cell biology

(2018) Hala Abou Assi et al.   NUCLEIC ACIDS RESEARCH

i-Motif-Binding Ligands and Their Effects on the Structure and Biological Functions of i-Motif

(2018) Shadi Sedghi Masoud et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide

(2018) Enrico Lavezzo et al.   PLoS Computational Biology

RNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF

(2017) Huilin Huang et al.   GENES & DEVELOPMENT

A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication

(2017) Sara Callegaro et al.   Scientific Reports

Visualization of DNA G-quadruplexes in herpes simplex virus 1-infected cells

(2016) Sara Artusi et al.   NUCLEIC ACIDS RESEARCH

TMPyP4 promotes cancer cell migration at low doses, but induces cell death at high doses

(2016) Xiao-Hui Zheng et al.   Scientific Reports

A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target

(2016) S.-R. Wang et al.   Science Advances

The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand

(2015) Sara Artusi et al.   ANTIVIRAL RESEARCH

G4-associated human diseases

(2015) N. Maizels   EMBO REPORTS

Global and Regional Estimates of Prevalent and Incident Herpes Simplex Virus Type 1 Infections in 2012

(2015) Katharine J. Looker et al.   PLoS One

Efficacy of Multiple Low-dose Photodynamic TMPYP4 Therapy on Cervical Cancer Tumour Growth in Nude Mice

(2014) Ai-Hong Liu et al.   Asian Pacific Journal of Cancer Prevention

Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies

(2014) Valentina Rapozzi et al.   Molecular Cancer

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

(2014) Aaron R. Haeusler et al.   NATURE

Two combined photosensitizers: a goal for more effective photodynamic therapy of cancer

(2014) P Acedo et al.   Cell Death & Disease

An Inquiry into the Molecular Basis of HSV Latency and Reactivation

(2013) Bernard Roizman et al.   Annual Review of Microbiology

TMPyP4 Porphyrin Distorts RNA G-quadruplex Structures of the Disease-associated r(GGGGCC)nRepeat of theC9orf72Gene and Blocks Interaction of RNA-binding Proteins

(2013) Bita Zamiri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vitro Assays Predictive of Telomerase Inhibitory Effect of G-Quadruplex Ligands in Cell Nuclei

(2013) Hidenobu Yaku et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Inhibition of the Host Translation Shutoff Response by Herpes Simplex Virus 1 Triggers Nuclear Envelope-Derived Autophagy

(2013) K. Radtke et al.   JOURNAL OF VIROLOGY

Bcl-2 Promoter Sequence G-Quadruplex Interactions with Three Planar and Non-Planar Cationic Porphyrins: TMPyP4, TMPyP3, and TMPyP2

(2013) Vu H. Le et al.   PLoS One

Formation of a Unique Cluster of G-Quadruplex Structures in the HIV-1 nef Coding Region: Implications for Antiviral Activity

(2013) Rosalba Perrone et al.   PLoS One

The Herpes Simplex Virus 1 Us11 Protein Inhibits Autophagy through Its Interaction with the Protein Kinase PKR

(2012) M. Lussignol et al.   JOURNAL OF VIROLOGY

The porphyrin TmPyP4 unfolds the extremely stable G-quadruplex in MT3-MMP mRNA and alleviates its repressive effect to enhance translation in eukaryotic cells

(2012) Mark J. Morris et al.   NUCLEIC ACIDS RESEARCH

Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5′-(C3TA2)4-3′ sequence of the human telomere

(2011) Sergio Fernández et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines

(2011) Jun Fujimori et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Monomorphic RNA G-Quadruplex and Polymorphic DNA G-Quadruplex Structures Responding to Cellular Environmental Factors

(2010) Dong-Hao Zhang et al.   BIOCHEMISTRY

Targeting G-Quadruplex DNA with Small Molecules

(2009) Nathan W. Luedtke   CHIMIA

Shedding Light on the Interaction between TMPyP4 and Human Telomeric Quadruplexes

(2009) Luigi Martino et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Role for G-Quadruplex RNA Binding by Epstein-Barr Virus Nuclear Antigen 1 in DNA Replication and Metaphase Chromosome Attachment

(2009) J. Norseen et al.   JOURNAL OF VIROLOGY

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

(2008) Yong Qin et al.   BIOCHIMIE

The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents

(2008) D. Sun et al.   MOLECULAR CANCER THERAPEUTICS

Antitumor activity of G-quadruplex–interactive agent TMPyP4 in K562 leukemic cells

(2007) Yoko Mikami-Terao et al.   CANCER LETTERS