Inorganic Polyphosphate in Host and Microbe Biology

The Role of Polyphosphate in Motility, Adhesion, and Biofilm Formation in Sulfolobales

(2021) Alejandra Recalde et al.   Microorganisms

Methods for the Analysis of Polyphosphate in the Life Sciences

(2020) Jonas Johannes Christ et al.   ANALYTICAL CHEMISTRY

Inorganic polyphosphate is produced and hydrolyzed in F0F1-ATP synthase of mammalian mitochondria

(2020) Artyom Y. Baev et al.   BIOCHEMICAL JOURNAL

Interactions between DksA and stress-responsive alternative sigma factors control inorganic polyphosphate accumulation in Escherichia coli

(2020) Michael J. Gray   JOURNAL OF BACTERIOLOGY

Polyphosphate induces the proteolysis of ADP-bound fraction of initiator to inhibit DNA replication initiation upon stress in Escherichia coli

(2020) Marta H Gross et al.   NUCLEIC ACIDS RESEARCH

Bacterial polyphosphates interfere with the innate host defense to infection

(2020) Julian Roewe et al.   Nature Communications

Diversification of polyphosphate end-labeling via bridging molecules

(2020) Catherine J. Baker et al.   PLoS One

Polyphosphate is an extracellular signal that can facilitate bacterial survival in eukaryotic cells

(2020) Ramesh Rijal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin

(2020) Min Tang-Fichaux et al.   mSphere

Porphyromonas gingivalis initiates coagulation and secretes polyphosphates — A mechanism for sustaining chronic inflammation?

(2020) Jessica Neilands et al.   MICROBIAL PATHOGENESIS

Effect of large magnetotactic bacteria with polyphosphate inclusions on the phosphate profile of the suboxic zone in the Black Sea

(2019) Heide N. Schulz-Vogt et al.   ISME Journal

Assaying for Inorganic Polyphosphate in Bacteria

(2019) Arya Pokhrel et al.   Jove-Journal of Visualized Experiments

Inorganic polyphosphate accumulation in Escherichia coli is regulated by DksA but not by (p)ppGpp

(2019) Michael J. Gray   JOURNAL OF BACTERIOLOGY

Inorganic polyphosphate accumulation suppresses the dormancy response and virulence in Mycobacterium tuberculosis

(2019) Prabhakar Tiwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Reduced Level of Inorganic Polyphosphate Mobilizes Antioxidant and Manganese-Resistance Systems in Saccharomyces cerevisiae

(2019) Ludmila Trilisenko et al.   Cells

Extracellular Polyphosphate Promotes Macrophage and Fibrocyte Differentiation, Inhibits Leukocyte Proliferation, and Acts as a Chemotactic Agent for Neutrophils

(2019) Patrick M. Suess et al.   JOURNAL OF IMMUNOLOGY

Inorganic Polyphosphate Regulates AMPA and NMDA Receptors and Protects Against Glutamate Excitotoxicity via Activation of P2Y Receptors

(2019) Marta Maiolino et al.   JOURNAL OF NEUROSCIENCE

Possible mechanisms of polyphosphate-induced amyloid fibril formation of β2-microglobulin

(2019) Chun-ming Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescence enzymatic assay for bacterial polyphosphate kinase 1 (PPK1) as a platform for screening antivirulence molecules

(2019) Francisca Campos et al.   Infection and Drug Resistance

Novel Aspects of Extracellular Vesicles as Mediators of Cancer-Associated Thrombosis

(2019) Vitor H. Almeida et al.   Cells

The potential for polyphosphate metabolism in Archaea and anaerobic polyphosphate formation in Methanosarcina mazei

(2019) Fabiana S. Paula et al.   Scientific Reports

Enzymatic quantification and length determination of polyphosphate down to a chain length of two

(2018) Jonas Johannes Christ et al.   ANALYTICAL BIOCHEMISTRY

DNA ladders can be used to size polyphosphate resolved by polyacrylamide gel electrophoresis

(2018) Stephanie A. Smith et al.   ELECTROPHORESIS

Mutations in Escherichia coli Polyphosphate Kinase That Lead to Dramatically Increased In Vivo Polyphosphate Levels

(2018) Amanda K. Rudat et al.   JOURNAL OF BACTERIOLOGY

Discovery of potent polyphosphate kinase 1 (PPK1) inhibitors using structure-based exploration of PPK1Pharmacophoric space coupled with docking analyses

(2018) Rasha M. Bashatwah et al.   JOURNAL OF MOLECULAR RECOGNITION

Inhibition of IP6K1 suppresses neutrophil-mediated pulmonary damage in bacterial pneumonia

(2018) Qingming Hou et al.   Science Translational Medicine

Inorganic Polyphosphate Is Essential for Salmonella Typhimurium Virulence and Survival in Dictyostelium discoideum

(2018) Macarena A. Varas et al.   Frontiers in Cellular and Infection Microbiology

Transcriptional Responses to ppGpp and DksA

(2018) Richard L. Gourse et al.   Annual Review of Microbiology

Inorganic Polyphosphate and Cancer

(2018) E. V. Kulakovskaya et al.   BIOCHEMISTRY-MOSCOW

Bacterial Polyphosphate Kinases Revisited: Role in Pathogenesis and Therapeutic Potential

(2018) Lalit Kumar Gautam et al.   CURRENT DRUG TARGETS

Analytical polyphosphate extraction from Saccharomyces cerevisiae

(2018) Jonas Johannes Christ et al.   ANALYTICAL BIOCHEMISTRY

Bisphosphonic acids and related compounds as inhibitors of nucleotide- and polyphosphate-processing enzymes: A PPK1 and PPK2 case study

(2018) Małgorzata Burda-Grabowska et al.   Chemical Biology & Drug Design

Lon recognition of the replication initiator DnaA requires a bipartite degron

(2018) Jing Liu et al.   MOLECULAR MICROBIOLOGY

Polyphosphate kinase 1 of Burkholderia pseudomallei controls quorum sensing, RpoS and host cell invasion

(2018) Kitima Srisanga et al.   Journal of Proteomics

Polyphosphate metabolism by purple non-sulfur bacteria and its possible application on photo-microbial fuel cell

(2017) Yen-Chun Lai et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Commentary: What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence?

(2017) Laurence Van Melderen et al.   Frontiers in Microbiology

The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation

(2017) Jan-Ulrik Dahl et al.   Nature Microbiology

Dictyostelium discoideum as a surrogate host–microbe model for antivirulence screening in Pseudomonas aeruginosa PAO1

(2016) Catalina Bravo-Toncio et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

PhoB activation in non-limiting phosphate condition by the maintenance of high polyphosphate levels in the stationary phase inhibits biofilm formation in Escherichia coli

(2016) M. Grillo-Puertas et al.   MICROBIOLOGY-SGM

Differential regulation of polyphosphate genes in Pseudomonas aeruginosa

(2016) Nicolás Federico Villamil Munévar et al.   MOLECULAR GENETICS AND GENOMICS

Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI

(2016) Cristina Puy et al.   PLoS One

Inorganic polyphosphate in the microbial world. Emerging roles for a multifaceted biopolymer

(2016) Tomás Albi et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

phoUInactivation in Pseudomonas aeruginosa Enhances Accumulation of ppGpp and Polyphosphate

(2015) Luiz Gustavo de Almeida et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Polyphosphate, platelets, and coagulation

(2015) R. J. Travers et al.   International Journal of Laboratory Hematology

5-Aminosalicylic acid, a specific drug for ulcerative colitis

(2015) Øyvind Hauso et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Individual and Collective Contributions of Chaperoning and Degradation to Protein Homeostasis in E. coli

(2015) Younhee Cho et al.   Cell Reports

Polyphosphate, cyclic AMP, guanosine tetraphosphate, and c-di-GMP reduce in vitro Lon activity

(2014) Devon O Osbourne et al.   Bioengineered

Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels

(2013) S. Ghosh et al.   BLOOD

Polyphosphate kinase 1, a central node in the stress response network of Mycobacterium tuberculosis, connects the two-component systems MprAB and SenX3-RegX3 and the extracytoplasmic function sigma factor, sigma E

(2013) S. Sanyal et al.   MICROBIOLOGY-SGM

Polyphosphate and Its Diverse Functions in Host Cells and Pathogens

(2013) Silvia N. J. Moreno et al.   PLoS Pathogens

Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation

(2012) J. H. Morrissey et al.   BLOOD

Polyphosphate kinase 1 is required for the pathogenesis process of meningiticEscherichia coliK1 (RS218)

(2012) Liang Peng et al.   Future Microbiology

Aptamer-Mediated Inhibition ofMycobacterium tuberculosisPolyphosphate Kinase 2

(2011) Ka To Shum et al.   BIOCHEMISTRY

Salmonella typhimurium is pathogenic for Dictyostelium cells and subverts the starvation response

(2011) Alessio Sillo et al.   CELLULAR MICROBIOLOGY

The Professional Phagocyte Dictyostelium discoideum as a Model Host for Bacterial Pathogens

(2011) Salvatore Bozzaro et al.   CURRENT DRUG TARGETS

Generation and envelope protein analysis of internalization defective Brucella abortus mutants in professional phagocytes, RAW 264.7

(2011) Seung Bin Cha et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Polyphosphate - an ancient energy source and active metabolic regulator

(2011) Lucia Achbergerová et al.   Microbial Cell Factories

Polyphosphate exerts differential effects on blood clotting, depending on polymer size

(2010) S. A. Smith et al.   BLOOD

Role of a Burkholderia pseudomallei polyphosphate kinase in an oxidative stress response, motilities, and biofilm formation

(2010) Suda Tunpiboonsak et al.   JOURNAL OF MICROBIOLOGY

Inorganic Polyphosphate: Essential for Growth and Survival

(2009) Narayana N. Rao et al.   Annual Review of Biochemistry