Extracellular miRNAs and Cell–Cell Communication: Problems and Prospects

hnRNPA2B1 inhibits the exosomal export of miR-503 in endothelial cells

(2020) Jennifer Pérez-Boza et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Apoptotic cell-derived exosomes: messages from dying cells

(2020) Ramesh Kakarla et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles

(2020) Andrew M. Leidal et al.   NATURE CELL BIOLOGY

Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone

(2020) Ryan Reshke et al.   Nature Biomedical Engineering

RNA delivery by extracellular vesicles in mammalian cells and its applications

(2020) Killian O’Brien et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation

(2019) Srimeenakshi Srinivasan et al.   CELL

Transfer of Functional Cargo in Exomeres

(2019) Qin Zhang et al.   Cell Reports

Proteomes of exosomes from HPV(+) or HPV(-) head and neck cancer cells: differential enrichment in immunoregulatory proteins

(2019) Sonja Ludwig et al.   OncoImmunology

Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli

(2019) Heedoo Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An ARF6–Exportin-5 axis delivers pre-miRNA cargo to tumour microvesicles

(2019) James W. Clancy et al.   NATURE CELL BIOLOGY

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles

(2019) Chiara Cianciaruso et al.   Cell Reports

Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

(2019) Morayma M Temoche-Diaz et al.   eLife

Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins

(2018) Nasibeh Karimi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hepatoma cell-secreted exosomal microRNA-103 increases vascular permeability and promotes metastasis by targeting junction proteins

(2018) Jian-Hong Fang et al.   HEPATOLOGY

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

(2018) Haiying Zhang et al.   NATURE CELL BIOLOGY

Clinical utility of circulating non-coding RNAs — an update

(2018) Simone Anfossi et al.   Nature Reviews Clinical Oncology

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transfer of miRNA in Macrophage-Derived Exosomes Induces Drug Resistance in Pancreatic Adenocarcinoma

(2018) Yoav Binenbaum et al.   CANCER RESEARCH

Regulation of microRNA biogenesis and its crosstalk with other cellular pathways

(2018) Thomas Treiber et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effect of exosomal miRNA on cancer biology and clinical applications

(2018) Zhenqiang Sun et al.   Molecular Cancer

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression

(2017) Yun Teng et al.   Nature Communications

Reversible HuR‐microRNA binding controls extracellular export of miR‐122 and augments stress response

(2016) Kamalika Mukherjee et al.   EMBO REPORTS

Role of Alix in miRNA packaging during extracellular vesicle biogenesis

(2016) ALESSANDRA IAVELLO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular and extracellular microRNA: An update on localization and biological role

(2016) Julia A. Makarova et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

(2016) Andrew J. McKenzie et al.   Cell Reports

The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting

(2016) Laura Santangelo et al.   Cell Reports

Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

(2016) Matthew J Shurtleff et al.   eLife

Cells release subpopulations of exosomes with distinct molecular and biological properties

(2016) Eduard Willms et al.   Scientific Reports

Commitment of Annexin A2 in recruitment of microRNAs into extracellular vesicles

(2015) Keitaro Hagiwara et al.   FEBS LETTERS

Mechanisms of RNA loading into exosomes

(2015) Teresa Janas et al.   FEBS LETTERS

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

RNA-binding protein HuR sequesters microRNA-21 to prevent translation repression of proinflammatory tumor suppressor gene programmed cell death 4

(2015) D K Poria et al.   ONCOGENE

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

Annexin A2: Its Molecular Regulation and Cellular Expression in Cancer Development

(2014) Chi-Yun Wang et al.   DISEASE MARKERS

Regulation of exosome release by glycosphingolipids and flotillins

(2014) Santosh Phuyal et al.   FEBS Journal

Quantitative and stoichiometric analysis of the microRNA content of exosomes

(2014) J. R. Chevillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

Minimal mechanistic model of siRNA-dependent target RNA slicing by recombinant human Argonaute 2 protein

(2013) A. Deerberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab27 Effectors, Pleiotropic Regulators in Secretory Pathways

(2013) Mitsunori Fukuda   TRAFFIC

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Circulating miRNAs: cell–cell communication function?

(2013) A. Turchinovich et al.   Frontiers in Genetics

Alternative RISC assembly: Binding and repression of microRNA-mRNA duplexes by human Ago proteins

(2012) M. M. Janas et al.   RNA

Secreted microRNAs: a new form of intercellular communication

(2012) Xi Chen et al.   TRENDS IN CELL BIOLOGY

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

MicroRNAs in body fluids—the mix of hormones and biomarkers

(2011) Maria Angelica Cortez et al.   Nature Reviews Clinical Oncology

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

The MicroRNA Spectrum in 12 Body Fluids

(2010) J. A. Weber et al.   CLINICAL CHEMISTRY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional delivery of viral miRNAs via exosomes

(2010) D. M. Pegtel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caveolin-1 regulates the secretion and cytoprotection of Cyr61 in hyperoxic cell death

(2008) Yang Jin et al.   FASEB JOURNAL

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA