Synthesis and anticancer activity of chalcone–quinoxalin conjugates

Synthesis, biological evaluation and molecular modeling study of 2-amino-3,5-disubstituted-pyrazines as Aurora kinases inhibitors

(2020) Yong-Xin Bo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and anti-inflammatory evaluation of new chalcone derivatives bearing bispiperazine linker as IL-1β inhibitors

(2020) Yan-Ling Tang et al.   BIOORGANIC CHEMISTRY

Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

(2020) Thoraya A. Farghaly et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of quinoxaline derivatives as specific c-Met kinase inhibitors

(2020) Seung Chan Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of 3-(benzazol-2-yl)quinoxaline derivatives as potent anticancer compounds: Privileged structure-based design, synthesis, and bioactive evaluation in vitro and in vivo

(2019) Qing-Qing Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quinoxaline-PABA bipartite hybrid derivatization approach: Design and search for antimicrobial agents

(2019) Harun M. Patel et al.   JOURNAL OF MOLECULAR STRUCTURE

Antimicrobial evaluation and action mechanism of chalcone derivatives containing quinoxaline moiety

(2019) Rongjiao Xia et al.   MONATSHEFTE FUR CHEMIE

Ultrasound-assisted synthesis of novel chalcone, heterochalcone and bis-chalcone derivatives and the evaluation of their antioxidant properties and as acetylcholinesterase inhibitors

(2019) Efraín Polo et al.   BIOORGANIC CHEMISTRY

1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

(2019) Zhi Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective approach towards the synthesis of spiro-indeno [1,2- b ] quinoxaline pyrrolothiazoles as antioxidant and antiproliferative

(2018) Kailasam Saravana Mani et al.   TETRAHEDRON LETTERS

An Indole–Chalcone Inhibits Multidrug-Resistant Cancer Cell Growth by Targeting Microtubules

(2018) Hui Cong et al.   MOLECULAR PHARMACEUTICS

An insight into medicinal chemistry of anticancer quinoxalines

(2018) Tanu Kaushal et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antitumoral activity of quinoxaline derivatives: A systematic review

(2018) M. Montana et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages

(2017) Antonio J. Ruiz-Alcaraz et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Novel trans-Ferulic Acid Derivatives Containing a Chalcone Moiety as Potential Activator for Plant Resistance Induction

(2017) Xiuhai Gan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects

(2017) Mohamed Alswah et al.   MOLECULES

Synthesis and biological evaluation of novel coumarin-chalcone derivatives containing urea moiety as potential anticancer agents

(2017) Belma Zengin Kurt et al.   Arabian Journal of Chemistry

Design, synthesis and anti-HIV activity of novel quinoxaline derivatives

(2016) Saloni B. Patel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Antiviral Bioactivity of Novel 4-Thioquinazoline Derivatives Containing Chalcone Moiety

(2015) Zhihua Wan et al.   MOLECULES

Synthesis and anti-tumor activity evaluation of Matijin-Su derivatives

(2014) Bixue Xu et al.   BIOORGANIC CHEMISTRY

Antiobesity, antioxidant and cytotoxicity activities of newly synthesized chalcone derivatives and their metal complexes

(2014) Mohamed Ramadan El Sayed Aly et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Isoliquiritigenin, a chalcone compound, is a positive allosteric modulator of GABAA receptors and shows hypnotic effects

(2011) Suengmok Cho et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antiprotozoal activity of chloroquinoline based chalcones

(2011) Faisal Hayat et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vitro antitubercular and antimicrobial activities of 1-substituted quinoxaline-2,3(1H,4H)-diones

(2009) P. Ramalingam et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS