New candidates for CD4 T cell pathogenicity in experimental neuroinflammation and multiple sclerosis

Soluble IL-2RA Levels in Multiple Sclerosis Subjects and the Effect of Soluble IL-2RA on Immune Responses

(2014) L. M. Maier et al.   JOURNAL OF IMMUNOLOGY

Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS

(2014) E. Zastepa et al.   NEUROLOGY

IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells

(2014) R. Noster et al.   Science Translational Medicine

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

(2014) Felix J. Hartmann et al.   Nature Communications

Network-Based Multiple Sclerosis Pathway Analysis with GWAS Data from 15,000 Cases and 30,000 Controls

(2013) Sergio E. Baranzini et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Systemic Autoimmunity in TAM Triple Knockout Mice Causes Inflammatory Brain Damage and Cell Death

(2013) Qiutang Li et al.   PLoS One

Bach2 maintains T cells in a naive state by suppressing effector memory-related genes

(2013) S.-i. Tsukumo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling the heterogeneity of multiple sclerosis in animals

(2013) Sarah B. Simmons et al.   TRENDS IN IMMUNOLOGY

Transcriptional and Epigenetic Control of T Helper Cell Specification: Molecular Mechanisms Underlying Commitment and Plasticity

(2012) Yuka Kanno et al.   Annual Review of Immunology

Membrane microdomain organization, calcium signal, and NFAT activation as an important axis in polarized Th cell function

(2012) Emese Izsepi et al.   CYTOMETRY PART A

Regulation of T helper cell differentiation by interferon regulatory factor family members

(2012) Ruihua Zhang et al.   IMMUNOLOGIC RESEARCH

An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development

(2012) Amiya K Patra et al.   NATURE IMMUNOLOGY

Daclizumab Therapy for Multiple Sclerosis

(2012) Bibiana Bielekova   Neurotherapeutics

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

(2011) Nikolaos A. Patsopoulos et al.   ANNALS OF NEUROLOGY

Experimental autoimmune encephalomyelitis - achievements and prospective advances

(2011) HELENA BATOULIS et al.   APMIS

An Overview of a Wide Range of Functions of ZnT and Zip Zinc Transporters in the Secretory Pathway

(2011) Taiho KAMBE   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Downregulation of the transcription factor KLF4 is required for the lineage commitment of T cells

(2011) Xiaomin Wen et al.   CELL RESEARCH

Krüppel-like factor 4 (KLF4) directly regulates proliferation in thymocyte development and IL-17 expression during Th17 differentiation

(2011) Jie An et al.   FASEB JOURNAL

Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation

(2011) Guoliang Cui et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Regulator of G Protein Signaling-1 Selectively Regulates Gut T Cell Trafficking and Colitic Potential

(2011) D. L. Gibbons et al.   JOURNAL OF IMMUNOLOGY

Autoreactive Tbet-Positive CD4 T Cells Develop Independent of Classic Th1 Cytokine Signaling during Experimental Autoimmune Encephalomyelitis

(2011) Wen-I Yeh et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of Glucocorticoids in the Control of Neuroinflammation

(2011) N. Schweingruber et al.   JOURNAL OF NEUROENDOCRINOLOGY

Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis

(2011) Bianca Weinstock-Guttman et al.   Journal of Neuroinflammation

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation

(2011) Xinshou Ouyang et al.   Nature Communications

Genetic proof for the transient nature of the Th17 phenotype

(2010) Florian C. Kurschus et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells

(2010) Maria H. Lexberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis

(2010) Volker Siffrin et al.   IMMUNITY

Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions

(2010) Ahmed N. Hegazy et al.   IMMUNITY

Surprising new roles for PU.1 in the adaptive immune response

(2010) Sebastian Carotta et al.   IMMUNOLOGICAL REVIEWS

Vitamin D and inflammation

(2010) Xavier Guillot et al.   JOINT BONE SPINE

Multiple Sclerosis: Association with HL-A3

(2010) S. NAITO et al.   TISSUE ANTIGENS

Up-Regulation of Soluble Axl and Mer Receptor Tyrosine Kinases Negatively Correlates with Gas6 in Established Multiple Sclerosis Lesions

(2009) Jason G. Weinger et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis

(2009) L. Lian et al.   BLOOD

Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis

(2009) Verena Brucklacher-Waldert et al.   BRAIN

Heterogeneity and plasticity of T helper cells

(2009) Jinfang Zhu et al.   CELL RESEARCH

Late Developmental Plasticity in the T Helper 17 Lineage

(2009) Yun Kyung Lee et al.   IMMUNITY

Th9 and allergic disease

(2009) Pejman Soroosh et al.   IMMUNOLOGY

Plasticity of T-cell phenotype and function: the T helper type 17 example

(2009) Ariana Peck et al.   IMMUNOLOGY

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

(2009) David Bending et al.   JOURNAL OF CLINICAL INVESTIGATION

The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer

(2009) Jan M. Ehrchen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response

(2008) Steven J. Bensinger et al.   CELL

Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells

(2008) Monica Montes et al.   CLINICAL IMMUNOLOGY

The role of glucocorticoids and progestins in inflammatory, autoimmune, and infectious disease

(2008) A. Sasha Tait et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vitamin D as an immune modulator in multiple sclerosis, a review

(2008) Joost Smolders et al.   JOURNAL OF NEUROIMMUNOLOGY

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY