Mendelian randomization highlights insomnia as a risk factor for pain diagnoses

A comparison of robust Mendelian randomization methods using summary data

(2020) Eric A. W. Slob et al.   GENETIC EPIDEMIOLOGY

Biological and clinical insights from genetics of insomnia symptoms

(2019) Jacqueline M. Lane et al.   NATURE GENETICS

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

(2019) Philip R. Jansen et al.   NATURE GENETICS

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

(2019) Eleonora Porcu et al.   Nature Communications

Genome-wide association study of multisite chronic pain in UK Biobank

(2019) Keira J. A. Johnston et al.   PLoS Genetics

Use of Mendelian Randomization to Examine Causal Inference in Osteoporosis

(2019) Jie Zheng et al.   Frontiers in Endocrinology

Insomnia and risk of chronic musculoskeletal complaints: longitudinal data from the HUNT study, Norway

(2018) B. L. Uhlig et al.   BMC MUSCULOSKELETAL DISORDERS

Publisher Correction: Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Insomnia Really Hurts: Effect of a Bad Night's Sleep on Pain Increases With Insomnia Severity

(2018) Yishul Wei et al.   Frontiers in Psychiatry

Interpreting findings from Mendelian randomization using the MR-Egger method

(2017) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Do physical activity and body mass index modify the association between chronic musculoskeletal pain and insomnia? Longitudinal data from the HUNT study, Norway

(2017) Eivind S. Skarpsno et al.   JOURNAL OF SLEEP RESEARCH

Decreased alertness due to sleep loss increases pain sensitivity in mice

(2017) Chloe Alexandre et al.   NATURE MEDICINE

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Correction: Orienting the causal relationship between imprecisely measured traits using GWAS summary data

(2017) Gibran Hemani et al.   PLoS Genetics

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Bias due to participant overlap in two-sample Mendelian randomization

(2016) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Obesity and Multiple Sclerosis: A Mendelian Randomization Study

(2016) Lauren E. Mokry et al.   PLOS MEDICINE

LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants: Fig. 1.

(2015) Mitchell J. Machiela et al.   BIOINFORMATICS

Impact of musculoskeletal pain on insomnia onset: a prospective cohort study

(2014) N. K. Y. Tang et al.   RHEUMATOLOGY

The caudate: a key node in the neuronal network imbalance of insomnia?

(2013) Diederick Stoffers et al.   BRAIN

Comorbid insomnia in patients with chronic pain: a study based on the Swedish quality registry for pain rehabilitation (SQRP)

(2013) Peter Alföldi et al.   DISABILITY AND REHABILITATION

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

The Association of Sleep and Pain: An Update and a Path Forward

(2013) Patrick H. Finan et al.   JOURNAL OF PAIN

The role of pain, physical disability, and reduced social participation in insomnia onset in community dwelling older adults: a prospective cohort study

(2013) Nicole K Y Tang et al.   LANCET

Chronic insomnia

(2012) Charles M Morin et al.   LANCET

Chapter 11: Genome-Wide Association Studies

(2012) William S. Bush et al.   PLoS Computational Biology

Pain sensitivity and modulation in primary insomnia

(2011) M. Haack et al.   EUROPEAN JOURNAL OF PAIN

Evidence for Shared Pain Mechanisms in Osteoarthritis, Low Back Pain, and Fibromyalgia

(2011) Roland Staud   Current Rheumatology Reports

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS