Identification of a nuclear receptor/coactivator developmental signaling pathway in the nematode parasite Strongyloides stercoralis

Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation

(2020) Katherine Omueti Ayoade et al.   Parasites & Vectors

RNAi-mediated knockdown of daf-12 in the model parasitic nematode Strongyloides ratti

(2019) Alex Dulovic et al.   PLoS Pathogens

Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

(2019) Guangxu Ma et al.   PLoS Pathogens

Heritable genetic transformation of Strongyloides stercoralis by microinjection of plasmid DNA constructs into the male germline

(2017) Hongguang Shao et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Nuclear receptors: emerging drug targets for parasitic diseases

(2017) Zhu Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Methylprednisolone acetate induces, and Δ7-dafachronic acid suppresses,Strongyloides stercoralishyperinfection in NSG mice

(2017) John B. Patton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted mutagenesis in a human-parasitic nematode

(2017) Spencer S. Gang et al.   PLoS Pathogens

Strongyloidiasis: A Disease of Socioeconomic Disadvantage

(2016) Meruyert Beknazarova et al.   International Journal of Environmental Research and Public Health

Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid

(2016) Mennatallah M. Y. Albarqi et al.   PLoS Pathogens

Widespread anthelmintic resistance in European farmed ruminants: a systematic review

(2015) H. Rose et al.   VETERINARY RECORD

The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes

(2015) Zhu Wang et al.   PLoS Genetics

Helminth Elimination in the Pursuit of Sustainable Development Goals: A "Worm Index" for Human Development

(2015) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases

Comparative Metabolomics Reveals Endogenous Ligands of DAF-12, a Nuclear Hormone Receptor, Regulating C. elegans Development and Lifespan

(2014) Parag Mahanti et al.   Cell Metabolism

cGMP and NHR Signaling Co-regulate Expression of Insulin-Like Peptides and Developmental Activation of Infective Larvae in Strongyloides stercoralis

(2014) Jonathan D. Stoltzfus et al.   PLoS Pathogens

The dauer hypothesis and the evolution of parasitism: 20years on and still going strong

(2013) Matt Crook   INTERNATIONAL JOURNAL FOR PARASITOLOGY

RNAseq Analysis of the Parasitic Nematode Strongyloides stercoralis Reveals Divergent Regulation of Canonical Dauer Pathways

(2012) Jonathan D. Stoltzfus et al.   PLoS Neglected Tropical Diseases

Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes

(2009) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans

(2009) C. M. Hammell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Hormone Receptor Regulation of MicroRNAs Controls Developmental Progression

(2009) Axel Bethke et al.   SCIENCE

A Conserved Endocrine Mechanism Controls the Formation of Dauer and Infective Larvae in Nematodes

(2008) Akira Ogawa et al.   CURRENT BIOLOGY