Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

(2019) Masaru Kanekiyo et al.   NATURE IMMUNOLOGY

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques

(2019) Amelia Escolano et al.   NATURE

Protect, modify, deprotect (PMD): A strategy for creating vaccines to elicit antibodies targeting a specific epitope

(2019) Payton A. Weidenbacher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model

(2019) Wen-Chun Liu et al.   Frontiers in Immunology

Engineering a Rugged Nanoscaffold to Enhance Plug-and-Display Vaccination

(2018) Theodora Ulli Jordanka Bruun et al.   ACS Nano

Towards a universal influenza vaccine: different approaches for one goal

(2018) Giuseppe A. Sautto et al.   Virology Journal

New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue

(2018) Karl D. Brune et al.   Frontiers in Immunology

Influenza

(2018) Florian Krammer et al.   Nature Reviews Disease Primers

Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview

(2018) Ahmed Mostafa et al.   Viruses-Basel

Subdominance and poor intrinsic immunogenicity limit humoral immunity targeting influenza HA stem

(2018) Hyon-Xhi Tan et al.   JOURNAL OF CLINICAL INVESTIGATION

Automated tilt series alignment and tomographic reconstruction in IMOD

(2017) David N. Mastronarde et al.   JOURNAL OF STRUCTURAL BIOLOGY

Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging

(2017) Wim J.H. Hagen et al.   JOURNAL OF STRUCTURAL BIOLOGY

Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in V H 1-69 Antibody Orientation on the HA Stem

(2017) Shanshan Lang et al.   Cell Reports

A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies

(2017) Raffael Nachbagauer et al.   npj Vaccines

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

(2016) M. Gordon Joyce et al.   CELL

Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages

(2016) Mihails Shishovs et al.   JOURNAL OF MOLECULAR BIOLOGY

Design of a hyperstable 60-subunit protein icosahedron

(2016) Yang Hsia et al.   NATURE

Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

(2016) Karl D. Brune et al.   Scientific Reports

Viral Receptor-Binding Site Antibodies with Diverse Germline Origins

(2015) Aaron G. Schmidt et al.   CELL

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

(2015) A. Impagliazzo et al.   SCIENCE

Influenza virus antigenicity and broadly neutralizing epitopes

(2015) Gillian M Air   Current Opinion in Virology

Flow Cytometry Reveals that H5N1 Vaccination Elicits Cross-Reactive Stem-Directed Antibodies from Multiple Ig Heavy-Chain Lineages

(2014) J. R. R. Whittle et al.   JOURNAL OF VIROLOGY

Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues

(2013) A. P. West et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses

(2011) D. C. Ekiert et al.   SCIENCE

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

(2010) J. D. Bloom et al.   SCIENCE

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE