Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

Repeated annual influenza vaccination and vaccine effectiveness: review of evidence

(2017) Edward A. Belongia et al.   Expert Review of Vaccines

Elicitation of Protective Antibodies against a Broad Panel of H1N1 Viruses in Ferrets Preimmune to Historical H1N1 Influenza Viruses

(2017) Donald M. Carter et al.   JOURNAL OF VIROLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

(2017) Donald D. Raymond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses

(2017) Chenguang Shen et al.   Science Translational Medicine

A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action

(2017) Ning Chai et al.   Nature Communications

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

(2016) M. Gordon Joyce et al.   CELL

Antibody-guided vaccine design: identification of protective epitopes

(2016) Antonio Lanzavecchia et al.   CURRENT OPINION IN IMMUNOLOGY

Heads, stalks and everything else: how can antibodies eradicate influenza as a human disease?

(2016) Karlynn E Neu et al.   CURRENT OPINION IN IMMUNOLOGY

Design and Characterization of a Computationally Optimized Broadly Reactive Hemagglutinin Vaccine for H1N1 Influenza Viruses

(2016) Donald M. Carter et al.   JOURNAL OF VIROLOGY

Structural and molecular basis for Ebola virus neutralization by protective human antibodies

(2016) J. Misasi et al.   SCIENCE

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

Viral Receptor-Binding Site Antibodies with Diverse Germline Origins

(2015) Aaron G. Schmidt et al.   CELL

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

(2015) Masaru Kanekiyo et al.   CELL

H5N1 Vaccine–Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem

(2015) Adam K. Wheatley et al.   JOURNAL OF IMMUNOLOGY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Semi-automated selection of cryo-EM particles in RELION-1.3

(2015) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody

(2015) Xiaoli Xiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

(2015) A. Impagliazzo et al.   SCIENCE

Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera

(2015) Joan O. Ngwuta et al.   Science Translational Medicine

Influenza virus antigenicity and broadly neutralizing epitopes

(2015) Gillian M Air   Current Opinion in Virology

Strategies to guide the antibody affinity maturation process

(2015) Nicole A Doria-Rose et al.   Current Opinion in Virology

Flow Cytometry Reveals that H5N1 Vaccination Elicits Cross-Reactive Stem-Directed Antibodies from Multiple Ig Heavy-Chain Lineages

(2014) J. R. R. Whittle et al.   JOURNAL OF VIROLOGY

Conserved Neutralizing Epitope at Globular Head of Hemagglutinin in H3N2 Influenza Viruses

(2014) Y. Iba et al.   JOURNAL OF VIROLOGY

Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection

(2014) V. V. A. Mallajosyula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor mimicry by antibody F045–092 facilitates universal binding to the H3 subtype of influenza virus

(2014) Peter S. Lee et al.   Nature Communications

Integrating influenza antigenic dynamics with molecular evolution

(2014) Trevor Bedford et al.   eLife

Prime-Boost Interval Matters: A Randomized Phase 1 Study to Identify the Minimum Interval Necessary to Observe the H5 DNA Influenza Vaccine Priming Effect

(2013) Julie E. Ledgerwood, Kathryn Zephir, Zonghui Hu, Chih-Jen Wei, LeeJah Chang, Mary E. Enama, Cynthia S. Hendel, Sandra Sitar, Robert T. Bailer, Richard A. Koup, John R. Mascola, Gary J. Nabel, Barney S. Graham et al.   JOURNAL OF INFECTIOUS DISEASES

Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site

(2013) M. Hong et al.   JOURNAL OF VIROLOGY

Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies

(2013) F. Krammer et al.   JOURNAL OF VIROLOGY

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

(2013) Masaru Kanekiyo et al.   NATURE

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution

(2013) B. F. Koel et al.   SCIENCE

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

(2012) R. Hai et al.   JOURNAL OF VIROLOGY

Cross-neutralization of influenza A viruses mediated by a single antibody loop

(2012) Damian C. Ekiert et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

(2012) G.-M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity

(2012) P. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Conserved Protective Epitopes on Influenza B Viruses

(2012) C. Dreyfus et al.   SCIENCE

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Broadly Neutralizing Human Monoclonal Antibody That Recognizes a Conserved, Novel Epitope on the Globular Head of the Influenza H1N1 Virus Hemagglutinin

(2011) J. C. Krause et al.   JOURNAL OF VIROLOGY

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

(2011) J. R. R. Whittle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

(2011) D. Corti et al.   SCIENCE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Historical thoughts on influenza viral ecosystems, or behold a pale horse, dead dogs, failing fowl, and sick swine

(2010) David M. Morens et al.   Influenza and Other Respiratory Viruses

Influenza Vaccines for the Future

(2010) Linda C. Lambert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

(2010) R. Xu et al.   SCIENCE

Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination

(2010) C.-J. Wei et al.   SCIENCE

Cloning and expression of murine Ig genes from single B cells

(2009) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Historical Perspective — Emergence of Influenza A (H1N1) Viruses

(2009) Shanta M. Zimmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

(2008) Xiaocong Yu et al.   NATURE

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH