Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy

Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats

(2020) Jing Yu et al.   Oxidative Medicine and Cellular Longevity

The Protective Effects and Mechanisms of Apelin/APJ System on Ischemic Stroke: A Promising Therapeutic Target

(2020) Yanjun Tian et al.   Frontiers in Neurology

Melatonin ameliorates excessive PINK1/Parkin-mediated mitophagy by enhancing SIRT1 expression in granulosa cells of PCOS

(2020) Shanling Yi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Apelin/APJ System in Psychosis and Neuropathy

(2020) Shuang-Yu Lv et al.   Frontiers in Pharmacology

Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis

(2020) Tao Liu et al.   LIFE SCIENCES

Physical exercise may exert its therapeutic influence on Alzheimer's disease through the reversal of mitochondrial dysfunction via SIRT1-FOXO1/3-PINK1-Parkin–mediated mitophagy

(2020) Na Zhao et al.   Journal of Sport and Health Science

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

Apelin-36 exerts the cytoprotective effect against MPP+-induced cytotoxicity in SH-SY5Y cells through PI3K/Akt/mTOR autophagy pathway

(2019) Junge Zhu et al.   LIFE SCIENCES

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation

(2019) Cristina Guardia-Laguarta et al.   JOURNAL OF NEUROSCIENCE

Polydatin Attenuates Neuronal Loss via Reducing Neuroinflammation and Oxidative Stress in Rat MCAO Models

(2019) Fawad Ali Shah et al.   Frontiers in Pharmacology

Mitochondria in Health and Disease

(2019) Sarah J. Annesley et al.   Cells

Acetyl-11-keto-β-boswellic acid (AKBA) Attenuates Oxidative Stress, Inflammation, Complement Activation and Cell Death in Brain Endothelial Cells Following OGD/Reperfusion

(2019) Saif Ahmad et al.   NEUROMOLECULAR MEDICINE

ROS-Mediated Mitochondrial Dysfunction and ER Stress Contribute to Compression-Induced Neuronal Injury

(2019) Tao Chen et al.   NEUROSCIENCE

Apelin-36 mitigates MPTP/MPP+-induced neurotoxicity: Involvement of α-synuclein and endoplasmic reticulum stress

(2019) Junge Zhu et al.   BRAIN RESEARCH

Mitochondrial dysfunction in neurodegenerative diseases and drug targets via apoptotic signaling

(2019) Yuanbo Wu et al.   MITOCHONDRION

Electroacupuncture ameliorates neuronal injury by Pink1/Parkin-mediated mitophagy clearance in cerebral ischemia-reperfusion

(2019) Huanyuan Wang et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Apelin-36 mediates neuroprotective effects by regulating oxidative stress, autophagy and apoptosis in MPTP-induced Parkinson’s disease model mice

(2019) Junge Zhu et al.   BRAIN RESEARCH

Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway

(2018) Xinwei Wu et al.   BRAIN RESEARCH

Apelin-13 attenuates ER stress-mediated neuronal apoptosis by activating Gα i /Gα q -CK2 signaling in ischemic stroke

(2018) Fei Wu et al.   EXPERIMENTAL NEUROLOGY

Sikokianin A from Wikstroemia indica protects PC12 cells against OGD/R-induced injury via inhibiting oxidative stress and activating Nrf2

(2018) Huankai Yao et al.   NATURAL PRODUCT RESEARCH

A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma

(2018) Zhi-qiang Yao et al.   Cell Death & Disease

Diverse roles of mitochondria in ischemic stroke

(2018) Jenq-Lin Yang et al.   Redox Biology

Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury

(2018) Zhe Gong et al.   Journal of Neuroinflammation

Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies

(2018) Hasnaa A. Elfawy et al.   LIFE SCIENCES

Interplay between mitochondrial metabolism and oxidative stress in ischemic stroke: An epigenetic connection

(2017) Parimala Narne et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Low Dose of Apelin-36 Attenuates ER Stress-Associated Apoptosis in Rats with Ischemic Stroke

(2017) Jian Qiu et al.   Frontiers in Neurology

Molecular mechanisms of ROS production and oxidative stress in diabetes

(2016) P. Newsholme et al.   BIOCHEMICAL JOURNAL

Sirt1: Role Under the Condition of Ischemia/Hypoxia

(2016) Xiaofei Meng et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Nitric Oxide Homeostasis in Neurodegenerative Diseases

(2016) Luciana Hannibal   Current Alzheimer Research

Mitochondrial ROS regulation of proliferating cells

(2016) Lauren Diebold et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sirt1 and the Mitochondria

(2016)   MOLECULES AND CELLS

The critical roles of mitophagy in cerebral ischemia

(2016) Yan-Cheng Tang et al.   Protein & Cell

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

(2015) Lulu Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Neuroprotective effects of apelin-13 on experimental ischemic stroke through suppression of inflammation

(2015) Qing Xin et al.   PEPTIDES

Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

(2015) Joe Dan Dunn et al.   Redox Biology

Rapamycin attenuates mitochondrial dysfunction via activation of mitophagy in experimental ischemic stroke

(2014) Qiang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

Modulation of Mitochondrial Function and Autophagy Mediates Carnosine Neuroprotection Against Ischemic Brain Damage

(2014) Seung-Hoon Baek et al.   STROKE

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

(2013) Xiangnan Zhang et al.   Autophagy

Oxidative Stress and Pathophysiology of Ischemic Stroke: Novel Therapeutic Opportunities

(2013) Ramon Rodrigo et al.   CNS & Neurological Disorders-Drug Targets

Neuroprotection of apelin and its signaling pathway

(2012) Baohua Cheng et al.   PEPTIDES

JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry

(2012) A Perelman et al.   Cell Death & Disease

Detection of reactive oxygen species (ROS) by the oxidant-sensing probe 2′,7′-dichlorodihydrofluorescein diacetate in the cyanobacterium Anabaena variabilis PCC 7937

(2010) Rajesh P. Rastogi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitophagy

(2009) Aviva M. Tolkovsky   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH