A Matter of State: Diversity in Oligodendrocyte Lineage Cells

Developmental trajectory of oligodendrocyte progenitor cells in the human brain revealed by single cell RNA sequencing

(2020) Kelly Perlman et al.   GLIA

Preservation of a remote fear memory requires new myelin formation

(2020) Simon Pan et al.   NATURE NEUROSCIENCE

Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory

(2020) Fei Wang et al.   NATURE NEUROSCIENCE

Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation

(2020) Roberta Marisca et al.   NATURE NEUROSCIENCE

Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis

(2020) Bjoern Neumann et al.   Cell Stem Cell

Changes in the oligodendrocyte progenitor cell proteome with ageing

(2020) Alerie G de la Fuente et al.   MOLECULAR & CELLULAR PROTEOMICS

Motor learning promotes remyelination via new and surviving oligodendrocytes

(2020) Clara M. Bacmeister et al.   NATURE NEUROSCIENCE

Origins and Proliferative States of Human Oligodendrocyte Precursor Cells

(2020) Wei Huang et al.   CELL

Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age

(2019) Sonia Olivia Spitzer et al.   NEURON

Altered human oligodendrocyte heterogeneity in multiple sclerosis

(2019) Sarah Jäkel et al.   NATURE

Dynamics of oligodendrocyte generation in multiple sclerosis

(2019) Maggie S. Y. Yeung et al.   NATURE

Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment

(2019) Anna C. Geraghty et al.   NEURON

The evolving concept of cell identity in the single cell era

(2019) Samantha A. Morris   DEVELOPMENT

Neuronal vulnerability and multilineage diversity in multiple sclerosis

(2019) Lucas Schirmer et al.   NATURE

Niche stiffness underlies the ageing of central nervous system progenitor cells

(2019) Michael Segel et al.   NATURE

Single-cell transcriptomic profiling of the aging mouse brain

(2019) Methodios Ximerakis et al.   NATURE NEUROSCIENCE

Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells

(2019) Björn Neumann et al.   Cell Stem Cell

Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice

(2019) Patrick E. Steadman et al.   NEURON

Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination

(2019) Leslie Kirby et al.   Nature Communications

Endothelin signalling mediates experience-dependent myelination in the CNS

(2019) Matthew Swire et al.   eLife

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

(2018) Frédéric Lessard et al.   NATURE CELL BIOLOGY

Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex

(2018) Ethan G. Hughes et al.   NATURE NEUROSCIENCE

Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain

(2018) Robert A. Hill et al.   NATURE NEUROSCIENCE

Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner

(2018) Stanislaw Mitew et al.   Nature Communications

Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development

(2018) Sueli Marques et al.   DEVELOPMENTAL CELL

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

(2018) Ana Mendanha Falcão et al.   NATURE MEDICINE

Development and Functional Diversification of Cortical Interneurons

(2018) Lynette Lim et al.   NEURON

How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood?

(2018) Renee E. Pepper et al.   Frontiers in Cellular Neuroscience

In Vivo Regulation of Oligodendrocyte Precursor Cell Proliferation and Differentiation by the AMPA-Receptor Subunit GluA2

(2018) Ting-Jiun Chen et al.   Cell Reports

Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors

(2018) Jing Wang et al.   Cell Reports

Ca2+ activity signatures of myelin sheath formation and growth in vivo

(2017) Marion Baraban et al.   NATURE NEUROSCIENCE

Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo

(2017) Anna M. Krasnow et al.   NATURE NEUROSCIENCE

Regenerating CNS myelin — from mechanisms to experimental medicines

(2017) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions

(2017) Maryam K. Fard et al.   Science Translational Medicine

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival

(2017) Eleni Kougioumtzidou et al.   eLife

Electrophysiological properties of NG2 + cells: Matching physiological studies with gene expression profiles

(2016) Valerie A. Larson et al.   BRAIN RESEARCH

Changes in the proliferative capacity of NG2 cell subpopulations during postnatal development of the mouse hippocampus

(2016) Behrouz Moshrefi-Ravasdjani et al.   Brain Structure & Function

TheDrosophilaneurogenin Tap functionally interacts with the Wnt-PCP pathway to regulate neuronal extension and guidance

(2016) Liqun Yuan et al.   DEVELOPMENT

Rabies virus-mediated oligodendrocyte labeling reveals a single oligodendrocyte myelinates axons from distinct brain regions

(2016) Yasuyuki Osanai et al.   GLIA

The cell fate: senescence or quiescence

(2016) Menderes Yusuf Terzi et al.   MOLECULAR BIOLOGY REPORTS

Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism

(2016) Aiman S. Saab et al.   NEURON

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

(2016) S. Marques et al.   SCIENCE

Systematic Review of Pharmacological Properties of the Oligodendrocyte Lineage

(2016) Carla Marinelli et al.   Frontiers in Cellular Neuroscience

CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes

(2015) Marie E. Bechler et al.   CURRENT BIOLOGY

Actin Filament Turnover Drives Leading Edge Growth during Myelin Sheath Formation in the Central Nervous System

(2015) Schanila Nawaz et al.   DEVELOPMENTAL CELL

Neuronal activity and AMPA-type glutamate receptor activation regulates the morphological development of oligodendrocyte precursor cells

(2015) Jessica Fannon et al.   GLIA

NG2-glia and their functions in the central nervous system

(2015) L. Dimou et al.   GLIA

Myelin Proteolipid Protein Complexes with  v Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression

(2015) D. E. Harlow et al.   JOURNAL OF NEUROSCIENCE

Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration

(2015) S. Moyon et al.   JOURNAL OF NEUROSCIENCE

Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo

(2015) Sigrid Mensch et al.   NATURE NEUROSCIENCE

Neuronal activity biases axon selection for myelination in vivo

(2015) Jacob H Hines et al.   NATURE NEUROSCIENCE

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors

(2015) Hélène O. B. Gautier et al.   Nature Communications

Quiescent Hematopoietic Stem Cells Accumulate DNA Damage during Aging that Is Repaired upon Entry into Cell Cycle

(2014) Isabel Beerman et al.   Cell Stem Cell

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division

(2014) Robert A Hill et al.   NATURE NEUROSCIENCE

Potassium channels in cell cycle and cell proliferation

(2014) D. Urrego et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain

(2014) E. M. Gibson et al.   SCIENCE

Motor skill learning requires active central myelination

(2014) I. A. McKenzie et al.   SCIENCE

Neuregulin and BDNF Induce a Switch to NMDA Receptor-Dependent Myelination by Oligodendrocytes

(2014) Iben Lundgaard et al.   PLOS BIOLOGY

Postnatal Down-Regulation of the GABAA Receptor γ2 Subunit in Neocortical NG2 Cells Accompanies Synaptic-to-Extrasynaptic Switch in the GABAergic Transmission Mode

(2013) Maddalena Balia et al.   CEREBRAL CORTEX

NG2 Cells in White Matter But Not Gray Matter Proliferate in Response to PDGF

(2013) R. A. Hill et al.   JOURNAL OF NEUROSCIENCE

Oligodendrocyte Precursor Cells Are Accurate Sensors of Local K+ in Mature Gray Matter

(2013) P. P. Maldonado et al.   JOURNAL OF NEUROSCIENCE

Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain

(2013) Francesca Viganò et al.   NATURE NEUROSCIENCE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Molecular regulation of stem cell quiescence

(2013) Tom H. Cheung et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

Role of myelin plasticity in oscillations and synchrony of neuronal activity

(2013) S. Pajevic et al.   NEUROSCIENCE

Rejuvenation of Regeneration in the Aging Central Nervous System

(2012) Julia M. Ruckh et al.   Cell Stem Cell

Disruption of NMDA Receptors in Oligodendroglial Lineage Cells Does Not Alter Their Susceptibility to Experimental Autoimmune Encephalomyelitis or Their Normal Development

(2012) F. Guo et al.   JOURNAL OF NEUROSCIENCE

Properties and Fate of Oligodendrocyte Progenitor Cells in the Corpus Callosum, Motor Cortex, and Piriform Cortex of the Mouse

(2012) L. E. Clarke et al.   JOURNAL OF NEUROSCIENCE

A culture system to study oligodendrocyte myelination processes using engineered nanofibers

(2012) Seonok Lee et al.   NATURE METHODS

The GPR17 receptor in NG2 expressing cells: Focus on in vivocell maturation and participation in acute trauma and chronic damage

(2011) Enrica Boda et al.   GLIA

Dorsally and Ventrally Derived Oligodendrocytes Have Similar Electrical Properties but Myelinate Preferred Tracts

(2011) R. B. Tripathi et al.   JOURNAL OF NEUROSCIENCE

NMDA Receptor Signaling in Oligodendrocyte Progenitors Is Not Required for Oligodendrogenesis and Myelination

(2011) L. M. De Biase et al.   JOURNAL OF NEUROSCIENCE

Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells

(2011) Marzieh Zonouzi et al.   NATURE NEUROSCIENCE

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

(2011) S. Y. C. Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postnatal Switch from Synaptic to Extrasynaptic Transmission between Interneurons and NG2 Cells

(2010) M. Velez-Fort et al.   JOURNAL OF NEUROSCIENCE

NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease

(2010) R. B. Tripathi et al.   JOURNAL OF NEUROSCIENCE

The Fate of Synaptic Input to NG2 Glial Cells: Neurons Specifically Downregulate Transmitter Release onto Differentiating Oligodendroglial Cells

(2010) M. Kukley et al.   JOURNAL OF NEUROSCIENCE

Excitability and Synaptic Communication within the Oligodendrocyte Lineage

(2010) L. M. De Biase et al.   JOURNAL OF NEUROSCIENCE

Morphological and electrical properties of oligodendrocytes in the white matter of the corpus callosum and cerebellum

(2010) Yamina Bakiri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Adult-born SVZ progenitors receive transient synapses during remyelination in corpus callosum

(2010) Ainhoa Etxeberria et al.   NATURE NEUROSCIENCE

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

Impact of global cerebral ischemia on K+ channel expression and membrane properties of glial cells in the rat hippocampus

(2010) Helena Pivonkova et al.   NEUROCHEMISTRY INTERNATIONAL

Cell cycle dynamics of NG2 cells in the postnatal and ageing brain

(2010) Konstantina Psachoulia et al.   Neuron Glia Biology

Functional α7-containing nicotinic receptors of NG2-expressing cells in the hippocampus

(2009) Mateo Vélez-Fort et al.   GLIA

Neonatal and adult O4+oligodendrocyte lineage cells display different growth factor responses and different gene expression patterns

(2009) Grace Lin et al.   JOURNAL OF NEUROSCIENCE RESEARCH

NG2-expressing cells in the nervous system revealed by the NG2-EYFP-knockin mouse

(2008) Khalad Karram et al.   GENESIS

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

(2008) Leanne E Rivers et al.   NATURE NEUROSCIENCE

Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter

(2008) Ragnhildur Káradóttir et al.   NATURE NEUROSCIENCE