Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

Extensive astrocyte metabolism of γ‐aminobutyric acid ( GABA ) sustains glutamine synthesis in the mammalian cerebral cortex

(2020) Jens V. Andersen et al.   GLIA

Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease

(2020) Jens V. Andersen et al.   NEUROBIOLOGY OF DISEASE

Astrocyte Biomarkers in Alzheimer’s Disease

(2019) Stephen F. Carter et al.   TRENDS IN MOLECULAR MEDICINE

Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene

(2019) Henriette R. Frederiksen et al.   Stem Cell Research

Consequences of Metabolic Disruption in Alzheimer’s Disease Pathology

(2019) J. C. Ryu et al.   Neurotherapeutics

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

(2018) Brian A Gordon et al.   LANCET NEUROLOGY

A bell-shaped dependence between amyloidosis and GABA accumulation in astrocytes in a mouse model of Alzheimer's disease

(2018) Bianca Brawek et al.   NEUROBIOLOGY OF AGING

The genes associated with early-onset Alzheimer’s disease

(2018) Meng-Hui Dai et al.   Oncotarget

Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene

(2018) Henriette R. Frederiksen et al.   Stem Cell Research

Astrocyte dysfunction in Alzheimer disease

(2017) Crystal Acosta et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cell Biology of Astrocyte-Synapse Interactions

(2017) Nicola J. Allen et al.   NEURON

Impaired expression of GABA transporters in the human Alzheimer’s disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus

(2017) Tessa E. Fuhrer et al.   NEUROSCIENCE

Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

(2017) Abinaya Chandrasekaran et al.   Stem Cell Research

Aberrant iPSC-derived human astrocytes in Alzheimer's disease

(2017) V C Jones et al.   Cell Death & Disease

The role of astrocytes in amyloid production and Alzheimer's disease

(2017) Georgia R. Frost et al.   Open Biology

Neuroinflammation in Alzheimer's disease: Current evidence and future directions

(2016) Valeria Calsolaro et al.   Alzheimers & Dementia

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

Evidence For and Against a Pathogenic Role of Reduced γ-Secretase Activity in Familial Alzheimer’s Disease

(2016) Tanya Jayne et al.   JOURNAL OF ALZHEIMERS DISEASE

Defeating Alzheimer's disease and other dementias: a priority for European science and society

(2016) Bengt Winblad et al.   LANCET NEUROLOGY

The road to restoring neural circuits for the treatment of Alzheimer's disease

(2016) Rebecca G. Canter et al.   NATURE

Alterations in Cerebral Cortical Glucose and Glutamine Metabolism Precedes Amyloid Plaques in the APPswe/PSEN1dE9 Mouse Model of Alzheimer’s Disease

(2016) Jens V. Andersen et al.   NEUROCHEMICAL RESEARCH

Astrocytic GABA transporter activity modulates excitatory neurotransmission

(2016) Kim Boddum et al.   Nature Communications

Implications of GABAergic Neurotransmission in Alzheimer’s Disease

(2016) Yanfang Li et al.   Frontiers in Aging Neuroscience

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

(2015) Pierre J. Magistretti et al.   NEURON

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction

(2014) Marie Orre et al.   NEUROBIOLOGY OF AGING

The Glutamine–Glutamate/GABA Cycle: Function, Regional Differences in Glutamate and GABA Production and Effects of Interference with GABA Metabolism

(2014) Anne B. Walls et al.   NEUROCHEMICAL RESEARCH

Glial Asthenia and Functional Paralysis

(2014) Alexei Verkhratsky et al.   NEUROSCIENTIST

Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model

(2014) Zheng Wu et al.   Nature Communications

Astrocytes and Glutamate Homoeostasis in Alzheimer's Disease: A Decrease in Glutamine Synthetase, But Not in Glutamate Transporter-1, in the Prefrontal Cortex

(2013) Magdalena Kulijewicz-Nawrot et al.   ASN Neuro

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

(2013) Yan Zhao et al.   Oxidative Medicine and Cellular Longevity

Efficient Generation of Astrocytes from Human Pluripotent Stem Cells in Defined Conditions

(2013) Atossa Shaltouki et al.   STEM CELLS

GABA and Glutamate Transporters in Brain

(2013) Yun Zhou et al.   Frontiers in Endocrinology

Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA

(2013) Arne Schousboe et al.   Frontiers in Endocrinology

The  -Secretase-Derived C-Terminal Fragment of  APP, C99, But Not A , Is a Key Contributor to Early Intraneuronal Lesions in Triple-Transgenic Mouse Hippocampus

(2012) I. Lauritzen et al.   JOURNAL OF NEUROSCIENCE

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?

(2011) Markel Olabarria et al.   Molecular Neurodegeneration

Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice

(2011) Latha Devi et al.   NEUROBIOLOGY OF DISEASE

Reactive astrocytes give neurons less support: implications for Alzheimer's disease

(2010) Megan L. Steele et al.   NEUROBIOLOGY OF AGING

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

(2009) Paula I. Moreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Basal Cerebral Metabolism May Modulate the Cognitive Effects of A  in Mild Cognitive Impairment: An Example of Brain Reserve

(2009) A. D. Cohen et al.   JOURNAL OF NEUROSCIENCE

Astroglia in dementia and Alzheimer's disease

(2008) J J Rodríguez et al.   CELL DEATH AND DIFFERENTIATION