Mapping of Translocator Protein (18 kDa) in Peripheral Sterile Inflammatory Disease and Cancer through PET Imaging
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mapping of Translocator Protein (18 kDa) in Peripheral Sterile Inflammatory Disease and Cancer through PET Imaging
Authors
Keywords
-
Journal
MOLECULAR PHARMACEUTICS
Volume -, Issue -, Pages -
Publisher
American Chemical Society (ACS)
Online
2021-03-02
DOI
10.1021/acs.molpharmaceut.1c00002
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Anatomy of 18F-GE180, a failed radioligand for the TSPO protein
- (2020) Paolo Zanotti-Fregonara et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Quantitative Assessment of Arthritis Activity in Rheumatoid Arthritis Patients Using [11C]DPA-713 Positron Emission Tomography
- (2020) Maqsood Yaqub et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Versatile Dimerisation Process of Translocator Protein (TSPO) Revealed by an Extensive Sampling Based on a Coarse-Grained Dynamics Study
- (2020) Rajas Rao et al. Journal of Chemical Information and Modeling
- Advances in PET to assess pulmonary inflammation: A systematic review
- (2020) Laurence Vass et al. EUROPEAN JOURNAL OF RADIOLOGY
- Mitochondrial proteins: from biogenesis to functional networks
- (2019) Nikolaus Pfanner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Imaging in rheumatoid arthritis: the role of magnetic resonance imaging and computed tomography
- (2019) Mikkel Østergaard et al. Radiologia Medica
- Primary immunodeficiency and autoimmunity: A comprehensive review
- (2019) Laura Amaya-Uribe et al. JOURNAL OF AUTOIMMUNITY
- 18F-PBR06 PET/CT imaging for evaluating atherosclerotic plaques linked to macrophage infiltration
- (2019) He Zhang et al. NUCLEAR MEDICINE COMMUNICATIONS
- 18F-PBR06 PET/CT imaging of inflammation and differentiation of lung cancer in mice
- (2019) He Zhang et al. Nuclear Science and Techniques
- Modified benzoxazolone (ABO‐AA) based single photon emission computed tomography (SPECT) probes for 18 kDa translocator protein
- (2019) Pooja Srivastava et al. DRUG DEVELOPMENT RESEARCH
- Gadolinium-conjugated CB86: a novel TSPO-targeting MRI contrast agent for imaging of rheumatoid arthritis
- (2019) Zhenyu Hou et al. JOURNAL OF DRUG TARGETING
- Disease activity in rheumatoid arthritis is inversely related to cerebral TSPO binding assessed by [11C]PBR28 positron emission tomography
- (2019) A. Forsberg et al. JOURNAL OF NEUROIMMUNOLOGY
- Imaging disease activity of rheumatoid arthritis by macrophage targeting using second generation translocator protein positron emission tomography tracers
- (2019) S. T. G. Bruijnen et al. PLoS One
- Cigarette smoke, saliva, the translocator protein 18 kDa (TSPO), and oral cancer
- (2019) Rafael Nagler et al. ORAL DISEASES
- Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand 18F-GE-180 and comparison with 18F-FDG and DCE-MRI
- (2019) Marius de Groot et al. EJNMMI Research
- Vulnerable atherosclerotic plaque - a review of current concepts and advanced imaging
- (2018) Miloslav Spacek et al. BIOMEDICAL PAPERS-OLOMOUC
- Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO)
- (2018) Sanna Hellberg et al. Contrast Media & Molecular Imaging
- Assessment of TSPO in a Rat Experimental Autoimmune Myocarditis Model: A Comparison Study between [18F]Fluoromethyl-PBR28 and [18F]CB251
- (2018) Ga Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- 18F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with18F-FDG
- (2018) Seock-Jin Chung et al. JOURNAL OF NUCLEAR MEDICINE
- Myocardial Inflammation Predicts Remodeling and Neuroinflammation After Myocardial Infarction
- (2018) James T. Thackeray et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- [18F]FEPPA: Improved Automated Radiosynthesis, Binding Affinity, and Preliminary in Vitro Evaluation in Colorectal Cancer
- (2018) Neydher Berroterán-Infante et al. ACS Medicinal Chemistry Letters
- Comparison of 18F-GE-180 and dynamic 18F-FET PET in high grade glioma: a double-tracer pilot study
- (2018) Marcus Unterrainer et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Translocator Protein (TSPO) as a Potential Biomarker in Human Cancers
- (2018) Nimisha Bhoola et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18 F-FEDAA1106
- (2018) Simon Cuhlmann et al. Molecular Imaging
- In vivo imaging of activated macrophages by 18F-FEDAC, a TSPO targeting PET ligand, in the use of biologic disease-modifying anti-rheumatic drugs (bDMARDs)
- (2018) Seock-Jin Chung et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Monitoring the Progression of Chronic Liver Damage in Rats Using [18F]PBR06
- (2018) Shuo Huang et al. MOLECULAR IMAGING AND BIOLOGY
- TSPO PET for glioma imaging using the novel ligand 18F-GE-180: first results in patients with glioblastoma
- (2017) Nathalie L. Albert et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- 11C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than 11C-(R)-PK11195
- (2017) Masato Kobayashi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Immune modulation of some autoimmune diseases: the critical role of macrophages and neutrophils in the innate and adaptive immunity
- (2017) Kely Campos Navegantes et al. Journal of Translational Medicine
- Translocator Protein PET Imaging in a Preclinical Prostate Cancer Model
- (2017) Mohammed N. Tantawy et al. MOLECULAR IMAGING AND BIOLOGY
- Advances in positron emission tomography for the imaging of rheumatoid arthritis
- (2017) Nehal Narayan et al. RHEUMATOLOGY
- Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176—based on recent publications that measured specific-to-non-displaceable ratios
- (2017) Masahiro Fujita et al. EJNMMI Research
- Interleukin-33 regulates intestinal inflammation by modulating macrophages in inflammatory bowel disease
- (2017) Dong Hyuk Seo et al. Scientific Reports
- PET Imaging of Atherosclerotic Disease: Advancing Plaque Assessment from Anatomy to Pathophysiology
- (2016) Nicholas R. Evans et al. Current Atherosclerosis Reports
- Cigarette smoke effects on TSPO and VDAC expression in a cellular lung cancer model
- (2016) Moshe Gavish et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Molecular Imaging in Preclinical Models of IBD with Nuclear Imaging Techniques
- (2016) Eric Kaaru et al. INFLAMMATORY BOWEL DISEASES
- Prediction of key genes and miRNAs responsible for loss of muscle force in patients during an acute exacerbation of chronic obstructive pulmonary disease
- (2016) Yanhong Duan et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Depiction of microglial activation in aging and dementia: Positron emission tomography with [11C]DPA713 versus [11C](R)PK11195
- (2016) Masamichi Yokokura et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- 18-kDa translocator protein ligand 18F-FEMPA: Biodistribution and uptake into atherosclerotic plaques in mice
- (2016) Sanna Hellberg et al. JOURNAL OF NUCLEAR CARDIOLOGY
- 11 C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain
- (2016) Masamichi Ikawa et al. JOURNAL OF NUCLEAR MEDICINE
- Flutriciclamide (18F-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein
- (2016) Z. Fan et al. JOURNAL OF NUCLEAR MEDICINE
- Evaluation of TSPO PET Ligands [18F]VUIIS1009A and [18F]VUIIS1009B: Tracers for Cancer Imaging
- (2016) Dewei Tang et al. MOLECULAR IMAGING AND BIOLOGY
- Evaluating [11C]PBR28 PET for Monitoring Gut and Brain Inflammation in a Rat Model of Chemically Induced Colitis
- (2016) E. Kurtys et al. MOLECULAR IMAGING AND BIOLOGY
- Protein–protein interaction network analysis and identifying regulation microRNAs in asthmatic children
- (2015) Y. Chen et al. ALLERGOLOGIA ET IMMUNOPATHOLOGIA
- Molecular Mechanisms in Genetically Defined Autoinflammatory Diseases: Disorders of Amplified Danger Signaling
- (2015) Adriana Almeida de Jesus et al. Annual Review of Immunology
- Molecular imaging of inflammation in the ApoE -/- mouse model of atherosclerosis with IodoDPA
- (2015) Catherine A. Foss et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- TSPO as a target for glioblastoma therapeutics: Figure 1
- (2015) Eryn L. Werry et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The methodology of TSPO imaging with positron emission tomography
- (2015) Federico E. Turkheimer et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The 18-kDa mitochondrial translocator protein in gliomas: from the bench to bedside
- (2015) Karolina Janczar et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Molecular Mechanisms for Alcoholic Hepatitis Based on Analysis of Gene Expression Profile
- (2015) Minghui Liu et al. Hepatitis Monthly
- Overview of Immunodeficiency Disorders
- (2015) Nikita Raje et al. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
- The Effect of Cigarette Smoke on the Translocator Protein (TSPO) in Cultured Lung Cancer Cells
- (2015) Rafael Nagler et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Evaluation of PET Imaging Performance of the TSPO Radioligand [18F]DPA-714 in Mouse and Rat Models of Cancer and Inflammation
- (2015) Jinzi Zheng et al. MOLECULAR IMAGING AND BIOLOGY
- Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study
- (2015) Jason R. Buck et al. PLoS One
- Structure and activity of tryptophan-rich TSPO proteins
- (2015) Y. Guo et al. SCIENCE
- Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism
- (2015) F. Li et al. SCIENCE
- Utility of Translocator Protein (18 kDa) as a Molecular Imaging Biomarker to Monitor the Progression of Liver Fibrosis
- (2015) Akiko Hatori et al. Scientific Reports
- [18F]FEBMP: Positron Emission Tomography Imaging of TSPO in a Model of Neuroinflammation in Rats, and in vitro Autoradiograms of the Human Brain
- (2015) Anjani K. Tiwari et al. Theranostics
- Targeting activated hepatic stellate cells (aHSCs) for liver fibrosis imaging
- (2015) Dan Li et al. EJNMMI Research
- Facile synthesis of SSR180575 and discovery of 7-chloro- N , N ,5-trimethyl-4-oxo-3(6-[ 18 F]fluoropyridin-2-yl)-3,5-dihydro-4 H -pyridazino[4,5- b ]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer
- (2014) Yiu-Yin Cheung et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Alcoholic Hepatitis: Current Management
- (2014) Erin K. J. Spengler et al. DIGESTIVE DISEASES AND SCIENCES
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- Kinetic Modeling without Accounting for the Vascular Component Impairs the Quantification of [11C]PBR28 Brain PET Data
- (2014) Gaia Rizzo et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Characterization of a novel acetamidobenzoxazolone-based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain
- (2014) Anjani K. Tiwari et al. JOURNAL OF NEUROCHEMISTRY
- Detection of Subclinical Synovitis with Macrophage Targeting and Positron Emission Tomography in Patients with Rheumatoid Arthritis without Clinical Arthritis
- (2014) Y. Y. J. Gent et al. JOURNAL OF RHEUMATOLOGY
- In vivo Evaluation of Inflammatory Bowel Disease with the Aid of μPET and the Translocator Protein 18 kDa Radioligand [18F]DPA-714
- (2014) Nicholas Bernards et al. MOLECULAR IMAGING AND BIOLOGY
- Synthesis and evaluation of new18F-labelled acetamidobenzoxazolone-based radioligands for imaging of the translocator protein (18 kDa, TSPO) in the brain
- (2014) Anjani K. Tiwari et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Structure of the Mitochondrial Translocator Protein in Complex with a Diagnostic Ligand
- (2014) ukasz Jaremko et al. SCIENCE
- [18F]DPA-714 as a biomarker for positron emission tomography imaging of rheumatoid arthritis in an animal model
- (2014) Géraldine Pottier et al. ARTHRITIS RESEARCH & THERAPY
- Promising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis
- (2014) Yoony YJ Gent et al. ARTHRITIS RESEARCH & THERAPY
- Diagnostic role of fluorodeoxyglucose positron emission tomography-computed tomography in prostate cancer
- (2014) YIYAN LIU Oncology Letters
- Longitudinal PET Imaging of Muscular Inflammation Using 18F-DPA-714 and 18F-Alfatide II and Differentiation with Tumors
- (2014) Chenxi Wu et al. Theranostics
- Positron-Emission Tomography Imaging of the TSPO with [18F]FEPPA in a Preclinical Breast Cancer Model
- (2013) Neil Vasdev et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Fever of unknown origin
- (2013) A. Freedman et al. CLINICAL MEDICINE
- Drug Ligand-Induced Activation of Translocator Protein (TSPO) Stimulates Steroid Production by Aged Brown Norway Rat Leydig Cells
- (2013) J.-Y. Chung et al. ENDOCRINOLOGY
- 4D-PET/CT with [11C]-PK11195 and [11C]-d-deprenyl Does not Identify the Chronic Inflammation in Asymptomatic Abdominal Aortic Aneurysms
- (2013) G. Tegler et al. EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
- Imaging of carrageenan-induced local inflammation and adjuvant-induced systemic arthritis with [11C]PBR28 PET
- (2013) Xia Shao et al. NUCLEAR MEDICINE AND BIOLOGY
- Role of translocator protein in melanoma growth and progression
- (2012) Tatiana Ruksha et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Translocator Protein (TSPO) in Breast Cancer
- (2012) S. Mukherjee et al. CURRENT MOLECULAR MEDICINE
- Translocator protein (18kDa), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease
- (2012) Lin Xie et al. JOURNAL OF HEPATOLOGY
- Real Time Identification of Drug-Induced Liver Injury (DILI) through Daily Screening of ALT Results: A Prospective Pilot Cohort Study
- (2012) Helmi M'Kada et al. PLoS One
- PET Imaging of Lung Inflammation with [18F]FEDAC, a Radioligand for Translocator Protein (18 kDa)
- (2012) Akiko Hatori et al. PLoS One
- Inflammation after trauma: Microglial activation and traumatic brain injury
- (2011) Anil F. Ramlackhansingh et al. ANNALS OF NEUROLOGY
- Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomography
- (2011) O. Gaemperli et al. EUROPEAN HEART JOURNAL
- The natural history of nonalcoholic fatty liver disease with advanced fibrosis or cirrhosis: An international collaborative study
- (2011) Neeraj Bhala et al. HEPATOLOGY
- An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28
- (2011) David R Owen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Synthesis and Evaluation of Novel Carbon-11 Labeled Oxopurine Analogues for Positron Emission Tomography Imaging of Translocator Protein (18 kDa) in Peripheral Organs
- (2011) Katsushi Kumata et al. JOURNAL OF MEDICINAL CHEMISTRY
- Differential Expression of the 18 kDa Translocator Protein (TSPO) by Neoplastic and Inflammatory Cells in Mouse Tumors of Breast Cancer
- (2011) Jinzi Zheng et al. MOLECULAR PHARMACEUTICS
- Molecular imaging of gliomas with PET: Opportunities and limitations
- (2011) C. la Fougere et al. NEURO-ONCOLOGY
- F-18 FDG PET-CT for predicting survival in patients with recurrent glioma: a prospective study
- (2011) Amburanjan Santra et al. NEURORADIOLOGY
- The Sterile Inflammatory Response
- (2010) Kenneth L. Rock et al. Annual Review of Immunology
- Inflammatory Bowel Disease
- (2010) Arthur Kaser et al. Annual Review of Immunology
- Chronic high fat, high cholesterol supplementation decreases 18kDa Translocator Protein binding capacity in association with increased oxidative stress in rat liver and aorta
- (2010) Jasmina Dimitrova-Shumkovska et al. FOOD AND CHEMICAL TOXICOLOGY
- Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands
- (2010) D. R. J. Owen et al. JOURNAL OF NUCLEAR MEDICINE
- Morphological and Receptorial Changes in the Epididymal Adipose Tissue of Rats Subjected to a Stressful Stimulus
- (2010) Enrico Campioli et al. Obesity
- Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis
- (2009) J.L.E. Bird et al. ATHEROSCLEROSIS
- Translocator Protein Blockade Reduces Prostate Tumor Growth
- (2009) A. Fafalios et al. CLINICAL CANCER RESEARCH
- Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events
- (2009) Craig Lammert et al. HEPATOLOGY
- Decreased survival of subjects with elevated liver function tests during a 28-year follow-up
- (2009) Cecilia Söderberg et al. HEPATOLOGY
- Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
- (2009) Beatrix Bartok et al. IMMUNOLOGICAL REVIEWS
- Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease
- (2009) Caroll J. Beltrán et al. INFLAMMATORY BOWEL DISEASES
- Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker
- (2009) William C. Kreisl et al. NEUROIMAGE
- Microglial activation and amyloid deposition in mild cognitive impairment: A PET study
- (2009) A. Okello et al. NEUROLOGY
- Neuroligand binding endophenotypes in blood cells distinguish two subsets of borderline personality disorder patients
- (2009) Barbara Begni et al. NEUROSCIENCE LETTERS
- Diffuse Liver Disease: Strategies for Hepatic CT and MR Imaging
- (2009) Daniel T. Boll et al. RADIOGRAPHICS
- Noninvasive imaging of macrophages in rheumatoid synovitis using11C-(R)-PK11195 and positron emission tomography
- (2008) Conny J. van der Laken et al. ARTHRITIS AND RHEUMATISM
- Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques
- (2008) Iina Laitinen et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers
- (2008) Fabien Chauveau et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Molecular Imaging of Murine Intestinal Inflammation With 2-Deoxy-2-[18F]Fluoro-d-Glucose and Positron Emission Tomography
- (2008) Sarah Brewer et al. GASTROENTEROLOGY
- 2-Phenyl-imidazo[1,2-a]pyridine Compounds Containing Hydrophilic Groups as Potent and Selective Ligands for Peripheral Benzodiazepine Receptors: Synthesis, Binding Affinity and Electrophysiological Studies
- (2008) Nunzio Denora et al. JOURNAL OF MEDICINAL CHEMISTRY
- Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study
- (2008) Paul Edison et al. NEUROBIOLOGY OF DISEASE
- PET scanning of macrophages in patients with scleroderma fibrosing alveolitis
- (2008) Howard M. Branley et al. NUCLEAR MEDICINE AND BIOLOGY
- Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors
- (2008) Alan A. Wilson et al. NUCLEAR MEDICINE AND BIOLOGY
- Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors
- (2007) Masao Imaizumi et al. NEUROIMAGE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search