Cilostazol preconditioning alleviates cyclophosphamide-induced cardiotoxicity in male rats: Mechanistic insights into SIRT1 signaling pathway

DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation

(2019) Deli Zhang et al.   Nature Communications

Tetrahydrocurcumin Ameliorates Diabetic Cardiomyopathy by Attenuating High Glucose-Induced Oxidative Stress and Fibrosis via Activating the SIRT1 Pathway

(2019) Kaifeng Li et al.   Oxidative Medicine and Cellular Longevity

SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection

(2018) Nunzia D'Onofrio et al.   ANTIOXIDANTS & REDOX SIGNALING

Cardiomyocyte-specific deletion of Sirt1 gene sensitizes myocardium to ischaemia and reperfusion injury

(2018) Lin Wang et al.   CARDIOVASCULAR RESEARCH

Beneficial effects of Cilostazol on liver injury induced by common bile duct ligation in rats: Role of SIRT1 signaling pathway

(2018) Soad L Kabil   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Cilostazol ameliorates heart failure with preserved ejection fraction and diastolic dysfunction in obese and non-obese hypertensive mice

(2018) Sukka Santosh Reddy et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cilostazol Attenuates Retinal Oxidative Stress and Inflammation in a Streptozotocin-Induced Diabetic Animal Model

(2018) Po-Ting Yeh et al.   CURRENT EYE RESEARCH

Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: Old drug with a new vision

(2018) Ashif Iqubal et al.   LIFE SCIENCES

(−)-Epigallocatechin-3-gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions

(2017) Yang Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel

(2017) Ajit Vikram et al.   NATURE MEDICINE

SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice

(2017) Sai Ma et al.   Oxidative Medicine and Cellular Longevity

Protective effects of sirtuins in cardiovascular diseases: from bench to bedside

(2015) Stephan Winnik et al.   EUROPEAN HEART JOURNAL

Protective effect of cilostazol against doxorubicin-induced cardiomyopathy in mice

(2015) Jin Sin Koh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox regulation of FoxO transcription factors

(2015) Lars-Oliver Klotz et al.   Redox Biology

Mechanisms of Fatal Cardiotoxicity following High-Dose Cyclophosphamide Therapy and a Method for Its Prevention

(2015) Takuro Nishikawa et al.   PLoS One

Blueberry Anthocyanins-Enriched Extracts Attenuate Cyclophosphamide-Induced Cardiac Injury

(2015) Yunen Liu et al.   PLoS One

Effects of ischemic preconditioning and cilostazol on muscle ischemia-reperfusion injury in rats

(2014) Carlos Alberto da Silva Frias Neto et al.   Acta Cirurgica Brasileira

Sirtuin 1 (SIRT1) Activation Mediates Sildenafil Induced Delayed Cardioprotection against Ischemia-Reperfusion Injury in Mice

(2014) Mona Shalwala et al.   PLoS One

Resveratrol protects cardiomyocytes from oxidative stress through SIRT1 and mitochondrial biogenesis signaling pathways

(2013) Yong-guang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

SIRT1 activation by curcumin pretreatment attenuates mitochondrial oxidative damage induced by myocardial ischemia reperfusion injury

(2013) Yang Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardioprotective effect of Saraca indica against cyclophosphamide induced cardiotoxicity in rats: A biochemical, electrocardiographic and histopathological study

(2013) A. H. M Viswanatha Swamy et al.   INDIAN JOURNAL OF PHARMACOLOGY

Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism

(2013) M. Gertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT1 modulates MAPK pathways in ischemic–reperfused cardiomyocytes

(2012) Matteo Becatti et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pioglitazone Attenuates Cardiac Fibrosis and Hypertrophy in a Rat Model of Diabetic Nephropathy

(2012) Rania A. Elrashidy et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

(2012) Hongying Yang et al.   PLoS One

Cilostazol, a Type III Phosphodiesterase Inhibitor, Reduces Ischemia/Reperfusion-Induced Spinal Cord Injury

(2011) Mehmet Ali Sahin et al.   HEART SURGERY FORUM

Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice

(2011) Tsuneaki Kawashima et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Probucol Attenuates Cyclophosphamide-induced Oxidative Apoptosis, p53 and Bax Signal Expression in Rat Cardiac Tissues

(2011) Yousif A. Asiri   Oxidative Medicine and Cellular Longevity

Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion

(2010) Chiao-Po Hsu et al.   CIRCULATION

Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy

(2009) M. Sulaiman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1

(2009) S. B. Rajamohan et al.   MOLECULAR AND CELLULAR BIOLOGY

Cilostazol Inhibits Oxidative Stress–Induced Premature Senescence Via Upregulation of Sirt1 in Human Endothelial Cells

(2008) Hidetaka Ota et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Forkhead Transcription Factors and Cardiovascular Biology

(2008) Kyriakos N. Papanicolaou et al.   CIRCULATION RESEARCH