Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study

Neuroinflammation and protein aggregation co-localize across the frontotemporal dementia spectrum

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Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients

(2019) Maximilianos Elkouris et al.   Frontiers in Cellular Neuroscience

How to apply the movement disorder society criteria for diagnosis of progressive supranuclear palsy

(2019) Max‐Joseph Grimm et al.   MOVEMENT DISORDERS

Silencing of long noncoding RNA RP11‐476D10.1 enhances apoptosis and autophagy while inhibiting proliferation of papillary thyroid carcinoma cells via microRNA‐138‐5p‐dependent inhibition of LRRK2

(2019) Yinlong Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial

(2019) Adam L Boxer et al.   LANCET NEUROLOGY

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

(2019) Mike A Nalls et al.   LANCET NEUROLOGY

Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome

(2019) Edwin Jabbari et al.   JAMA Neurology

Replication of progressive supranuclear palsy genome-wide association study identifies SLCO1A2 and DUSP10 as new susceptibility loci

(2018) Monica Y. Sanchez-Contreras et al.   Molecular Neurodegeneration

[11C]PK11195 binding in Alzheimer disease and progressive supranuclear palsy

(2018) Luca Passamonti et al.   NEUROLOGY

LRRK2 kinase in Parkinson's disease

(2018) Dario R. Alessi et al.   SCIENCE

Variation at the TRIM 11 Locus Modifies Progressive Supranuclear Palsy Phenotype

(2018) Edwin Jabbari et al.   ANNALS OF NEUROLOGY

Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases

(2018) Jason A. Chen et al.   Molecular Neurodegeneration

Peripheral immune system in aging and Alzheimer’s disease

(2018) Wei Cao et al.   Molecular Neurodegeneration

Comprehensive functional genomic resource and integrative model for the human brain

(2018) Daifeng Wang et al.   SCIENCE

Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics

(2018) Farah H. Bardai et al.   PLOS BIOLOGY

G2019S LRRK2 enhances the neuronal transmission of tau in the mouse brain

(2017) An Phu Tran Nguyen et al.   HUMAN MOLECULAR GENETICS

Predictors of survival in progressive supranuclear palsy and multiple system atrophy: a systematic review and meta-analysis

(2017) Stella Andrea Glasmacher et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

(2017) Davina J Hensman Moss et al.   LANCET NEUROLOGY

Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria

(2017) Günter U. Höglinger et al.   MOVEMENT DISORDERS

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

(2017) Katrina M de Lange et al.   NATURE GENETICS

NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases

(2017) Cornelis Blauwendraat et al.   NEUROBIOLOGY OF AGING

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

What is the evidence that tau pathology spreads through prion-like propagation?

(2017) Amrit Mudher et al.   Acta Neuropathologica Communications

Extending the use of GWAS data by combining data from different genetic platforms

(2017) E. P. A. van Iperen et al.   PLoS One

Study ofLRRK2variation in tauopathy: Progressive supranuclear palsy and corticobasal degeneration

(2016) Monica Sanchez-Contreras et al.   MOVEMENT DISORDERS

Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes

(2016) Ian T.S. Coyle-Gilchrist et al.   NEUROLOGY

RNA splicing is a primary link between genetic variation and disease

(2016) Yang I. Li et al.   SCIENCE

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

(2015) Nicole Maphis et al.   BRAIN

LRRK2 Promotes Tau Accumulation, Aggregation and Release

(2015) Patrícia Silva Guerreiro et al.   MOLECULAR NEUROBIOLOGY

Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

(2014) Adam L Boxer et al.   LANCET NEUROLOGY

A phase 2 trial of the GSK-3 inhibitor tideglusib in progressive supranuclear palsy

(2014) Eduardo Tolosa et al.   MOVEMENT DISORDERS

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

(2013) Florence Clavaguera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LRRK2 Inhibition Attenuates Microglial Inflammatory Responses

(2012) M. S. Moehle et al.   JOURNAL OF NEUROSCIENCE

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

(2011) Günter U Höglinger et al.   NATURE GENETICS

Novel L284R MAPT Mutation in a Family with an Autosomal Dominant Progressive Supranuclear Palsy Syndrome

(2010) Jonathan D. Rohrer et al.   Neurodegenerative Diseases

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE