Nucleophilic Fluorination of Heteroaryl Chlorides and Aryl Triflates Enabled by Cooperative Catalysis

Where does the Fluorine come from? A review on the challenges associated with the synthesis of organofluorine compounds.

(2020) Stephane Caron   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The Most Common Functional Groups in Bioactive Molecules and How Their Popularity Has Evolved over Time

(2020) Peter Ertl et al.   JOURNAL OF MEDICINAL CHEMISTRY

General Synthesis of Tri-Carbo-Substituted N2-Aryl-1,2,3-triazoles via Cu-Catalyzed Annulation of Azirines with Aryldiazonium Salts

(2020) Fang-Fang Feng et al.   JOURNAL OF ORGANIC CHEMISTRY

The development of a commercial manufacturing route to 2-fluoroadenine, the key unnatural nucleobase of islatravir

(2020) Cynthia Marilyn Hong et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Hydrogen Bonding Phase-Transfer Catalysis with Potassium Fluoride: Enantioselective Synthesis of β-Fluoroamines

(2019) Gabriele Pupo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis

(2018) Gabriele Pupo et al.   SCIENCE

Controlled/Living Radical Polymerization of Semifluorinated (Meth)acrylates

(2018) Mao Chen et al.   SYNLETT

Nucleophilic Fluorination with Aqueous Bifluoride Solution: Effect of the Phase-Transfer Catalyst

(2018) Alicja Talko et al.   ACS Sustainable Chemistry & Engineering

Reactions of Arylsulfonate Electrophiles with NMe4F: Mechanistic Insight, Reactivity, and Scope

(2018) Sydonie D. Schimler et al.   JOURNAL OF ORGANIC CHEMISTRY

Selective Functionalization of Styrenes with Oxygen Using Different Electrode Materials: Olefin Cleavage and Synthesis of Tetrahydrofuran Derivatives

(2018) Yasushi Imada et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiple Approaches to the In Situ Generation of Anhydrous Tetraalkylammonium Fluoride Salts for SNAr Fluorination Reactions

(2017) Megan A. Cismesia et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd-Catalyzed Aerobic Oxidative Biaryl Coupling: Non-Redox Cocatalysis by Cu(OTf)2 and Discovery of Fe(OTf)3 as a Highly Effective Cocatalyst

(2017) Dian Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleophilic Deoxyfluorination of Phenols via Aryl Fluorosulfonate Intermediates

(2017) Sydonie D. Schimler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Evolution of Pd0/PdII-Catalyzed Aromatic Fluorination

(2016) Aaron C. Sather et al.   ACCOUNTS OF CHEMICAL RESEARCH

Rhodium-catalyzed transformation of heteroaryl aryl ethers into heteroaryl fluorides

(2016) Mieko Arisawa et al.   CHEMICAL COMMUNICATIONS

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

(2016) Yu Zhou et al.   CHEMICAL REVIEWS

18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography

(2016) Sean Preshlock et al.   CHEMICAL REVIEWS

Hydrogen-bond promoted nucleophilic fluorination: concept, mechanism and applications in positron emission tomography

(2016) Ji-Woong Lee et al.   CHEMICAL SOCIETY REVIEWS

Late-Stage Fluorination: Fancy Novelty or Useful Tool?

(2015) Constanze N. Neumann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Monofluorination of Organic Compounds: 10 Years of Innovation

(2015) Pier Alexandre Champagne et al.   CHEMICAL REVIEWS

Organofluorine chemistry: applications, sources and sustainability

(2015) Antal Harsanyi et al.   GREEN CHEMISTRY

Anhydrous Tetramethylammonium Fluoride for Room-Temperature SNAr Fluorination

(2015) Sydonie D. Schimler et al.   JOURNAL OF ORGANIC CHEMISTRY

Modern Carbon–Fluorine Bond Forming Reactions for Aryl Fluoride Synthesis

(2014) Michael G. Campbell et al.   CHEMICAL REVIEWS

Mild Fluorination of Chloropyridines with in Situ Generated Anhydrous Tetrabutylammonium Fluoride

(2014) Laura J. Allen et al.   JOURNAL OF ORGANIC CHEMISTRY

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Selective C-H Fluorination of Pyridines and Diazines Inspired by a Classic Amination Reaction

(2013) P. S. Fier et al.   SCIENCE

Transition metal catalysis and nucleophilic fluorination

(2011) Charlotte Hollingworth et al.   CHEMICAL COMMUNICATIONS

A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives

(2010) Nicholas A. McGrath et al.   JOURNAL OF CHEMICAL EDUCATION

Mechanism of C−F Reductive Elimination from Palladium(IV) Fluorides

(2010) Takeru Furuya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Safety Notables: Information from the Literature

(2010) Richard Barnhart et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Carbon-Fluorine Bond Formation for the Synthesis of Aryl Fluorides

(2010) Tobias Ritter et al.   SYNTHESIS-STUTTGART

Overview on the history of organofluorine chemistry from the viewpoint of material industry

(2009) Takashi OKAZOE   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

(2008) Kenneth L. Kirk   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS